1     M         1.024   1.047   1.109   1.210   1.235   1.314   1.054   1.089   1.181
2     G         0.157  -0.057  -0.176   0.181  -0.114  -0.382   0.171  -0.140  -0.365
3     G         0.157  -0.057  -0.176   0.230  -0.033  -0.238   0.171  -0.140  -0.365
4     I        -2.565  -2.388  -2.067  -2.628  -2.336  -1.949  -2.100  -1.923  -1.521
5     R        -1.446  -1.709  -1.607  -0.912  -1.306  -1.270  -1.217  -1.501  -1.332
6     E        -0.669  -0.783  -0.991  -0.579  -0.752  -1.141  -0.586  -0.731  -0.986
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     K        -0.669  -0.956  -1.011  -0.322  -0.715  -0.862  -0.586  -0.950  -1.010
9     K         1.024   1.047   1.109   1.060   1.095   1.189   1.054   1.089   1.181
10    A        -1.048  -0.905  -0.999  -1.339  -1.113  -1.214  -1.091  -0.892  -0.996
11    E        -1.218  -1.236  -1.039  -1.179  -1.191  -0.928  -1.343  -1.339  -1.047
12    Y         1.024   1.047   1.109   1.191   1.228   1.298   1.054   1.089   1.181
13    F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
14    A        -1.865  -1.950  -1.623  -2.048  -2.130  -1.654  -1.721  -1.757  -1.348
15    K         1.024   1.047   1.109   1.060   1.095   1.189   1.054   1.089   1.181
16    L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
17    R        -0.270  -0.319  -0.250  -0.112  -0.210  -0.182  -0.460  -0.555  -0.488
18    E        -1.446  -1.709  -1.607  -1.157  -1.537  -1.404  -1.217  -1.501  -1.332
19    Y        -0.498  -0.321  -0.224  -0.627  -0.382  -0.239  -0.838  -0.558  -0.444
20    L         0.157  -0.057  -0.176   0.216  -0.046  -0.211   0.171  -0.140  -0.365
21    E         0.157   0.143  -0.160   0.216   0.206  -0.151   0.171   0.149  -0.338
22    E        -0.669  -0.956  -1.011  -0.490  -0.863  -0.955  -0.586  -0.950  -1.010
23    Y         1.024   1.047   1.109   1.191   1.228   1.298   1.054   1.089   1.181
24    K        -0.669  -0.956  -1.011  -0.290  -0.663  -0.784  -0.586  -0.950  -1.010
25    S         1.024   1.047   1.109   0.942   0.983   1.091   1.054   1.089   1.181
26    L        -1.048  -0.958  -1.022  -1.009  -0.946  -1.070  -1.091  -1.018  -1.027
27    F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
28    V        -0.270  -0.260  -0.239  -0.448  -0.427  -0.425  -0.460  -0.457  -0.470
29    V         1.024   1.047   1.109   0.819   0.877   0.989   1.054   1.089   1.181
30    G        -0.669  -0.956  -1.011  -0.449  -0.822  -0.947  -0.586  -0.950  -1.010
31    V         0.157  -0.057  -0.176   0.117  -0.131  -0.323   0.171  -0.140  -0.365
32    D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
33    N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
34    V         1.024   1.047   1.109   0.819   0.877   0.989   1.054   1.089   1.181
35    S         1.024   1.047   1.109   0.942   0.983   1.091   1.054   1.089   1.181
36    S         1.024   1.047   1.109   0.942   0.983   1.091   1.054   1.089   1.181
37    Q         1.024   1.047   1.109   1.226   1.254   1.327   1.054   1.089   1.181
38    Q         1.024   1.047   1.109   1.226   1.254   1.327   1.054   1.089   1.181
39    M         1.024   1.047   1.109   1.210   1.235   1.314   1.054   1.089   1.181
40    H         1.024   1.047   1.109   1.295   1.323   1.385   1.054   1.089   1.181
41    E        -0.669  -0.728  -0.984  -0.457  -0.568  -0.845  -0.586  -0.687  -0.977
42    V        -0.571  -0.502  -0.266  -0.926  -0.817  -0.458  -0.964  -0.865  -0.515
43    R         1.024   1.047   1.109   1.140   1.175   1.256   1.054   1.089   1.181
44    K         0.157   0.061  -0.168   0.393   0.286  -0.031   0.171   0.033  -0.352
45    E        -2.813  -2.780  -2.430  -2.586  -2.520  -2.034  -2.100  -2.058  -1.637
46    L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
47    R         1.024   1.047   1.109   1.140   1.175   1.256   1.054   1.089   1.181
48    G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
49    R        -1.767  -1.852  -1.612  -1.403  -1.539  -1.309  -1.595  -1.648  -1.338
50    A         0.157   0.324  -0.146  -0.086   0.115  -0.445   0.171   0.390  -0.315
51    V        -0.669  -0.776  -0.988  -0.578  -0.732  -1.029  -0.586  -0.739  -0.982
52    V         0.157  -0.057  -0.176   0.105  -0.150  -0.356   0.171  -0.140  -0.365
53    L         0.157  -0.057  -0.176   0.198  -0.075  -0.262   0.171  -0.140  -0.365
54    M         1.024   1.047   1.109   1.210   1.235   1.314   1.054   1.089   1.181
55    G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
56    K         1.024   1.047   1.109   1.060   1.095   1.189   1.054   1.089   1.181
57    N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
58    T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
59    M         1.024   1.047   1.109   1.210   1.235   1.314   1.054   1.089   1.181
60    V         0.157  -0.057  -0.176   0.117  -0.131  -0.323   0.171  -0.140  -0.365
61    R         1.024   1.047   1.109   1.140   1.175   1.256   1.054   1.089   1.181
62    R         1.024   1.047   1.109   1.140   1.175   1.256   1.054   1.089   1.181
63    A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
64    I        -1.865  -1.803  -1.604  -1.786  -1.688  -1.428  -1.721  -1.636  -1.331
65    R         0.157   0.061  -0.168   0.449   0.334  -0.037   0.171   0.033  -0.352
66    G        -0.669  -0.783  -0.991  -0.465  -0.614  -0.955  -0.586  -0.731  -0.986
67    F         0.157  -0.057  -0.176   0.398   0.121  -0.112   0.171  -0.140  -0.365
68    L        -1.865  -1.853  -1.605  -1.869  -1.856  -1.553  -1.721  -1.670  -1.333
69    S        -1.767  -1.891  -1.617  -1.763  -1.980  -1.628  -1.595  -1.701  -1.343
70    D        -0.270  -0.162  -0.219  -0.266  -0.110  -0.280  -0.460  -0.302  -0.437
71    L        -1.446  -1.582  -1.595  -1.084  -1.286  -1.276  -1.217  -1.379  -1.321
72    P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
73    D        -0.498  -0.321  -0.224  -0.728  -0.458  -0.327  -0.838  -0.558  -0.444
74    F        -1.767  -1.781  -1.599  -1.418  -1.478  -1.374  -1.595  -1.578  -1.326
75    E         0.157   0.143  -0.160   0.129   0.111  -0.389   0.171   0.149  -0.338
76    K        -1.048  -1.161  -1.041  -0.829  -1.029  -0.902  -1.091  -1.255  -1.049
77    L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
78    L         0.157   0.270  -0.149   0.233   0.355  -0.128   0.171   0.321  -0.320
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
81    F        -0.669  -0.886  -1.000  -0.333  -0.656  -0.940  -0.586  -0.866  -0.997
82    V        -1.048  -0.875  -1.000  -1.027  -0.758  -0.902  -1.091  -0.851  -0.998
83    K        -0.498  -0.488  -0.265  -0.517  -0.524  -0.216  -0.838  -0.842  -0.515
84    G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
85    N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
86    V         1.024   1.047   1.109   0.819   0.877   0.989   1.054   1.089   1.181
87    G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
88    F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
89    V        -0.571  -0.459  -0.248  -0.926  -0.755  -0.439  -0.964  -0.792  -0.486
90    F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
91    T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
92    N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
93    E        -2.565  -2.472  -2.066  -2.530  -2.475  -1.925  -2.100  -1.989  -1.521
94    P        -1.048  -0.751  -0.995  -0.886  -0.487  -0.861  -1.091  -0.716  -0.992
95    L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
96    T        -0.669  -0.391  -0.958  -0.281   0.020  -0.689  -0.586  -0.252  -0.945
97    E        -1.767  -1.394  -1.565  -1.623  -1.151  -1.377  -1.595  -1.188  -1.294
98    I        -0.270  -0.408  -0.260  -0.344  -0.614  -0.440  -0.460  -0.704  -0.506
99    K        -0.498  -0.321  -0.224  -0.489  -0.213  -0.134  -0.838  -0.558  -0.444
100   N        -1.218  -1.040  -1.023  -1.265  -1.058  -0.959  -1.343  -1.143  -1.028
101   V        -1.767  -1.716  -1.608  -1.661  -1.620  -1.433  -1.595  -1.559  -1.335
102   I        -0.669  -0.510  -0.966  -0.455  -0.275  -0.965  -0.586  -0.403  -0.955
103   V        -1.369  -1.384  -1.069  -1.579  -1.622  -1.166  -1.469  -1.489  -1.080
104   S        -1.218  -1.104  -1.018  -1.589  -1.422  -1.253  -1.343  -1.172  -1.022
105   N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
106   R        -1.466  -1.360  -1.068  -1.549  -1.413  -1.001  -1.595  -1.464  -1.078
107   V         0.157  -0.057  -0.176   0.117  -0.131  -0.323   0.171  -0.140  -0.365
108   A         0.157   0.143  -0.160  -0.091  -0.097  -0.480   0.171   0.149  -0.338
109   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
110   P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
111   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
112   R         0.157   0.270  -0.149   0.449   0.578  -0.005   0.171   0.321  -0.320
113   A        -0.669  -0.728  -0.984  -0.761  -0.844  -1.127  -0.586  -0.687  -0.977
114   G         0.157  -0.057  -0.176   0.247  -0.006  -0.191   0.171  -0.140  -0.365
115   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
116   V        -0.498  -0.502  -0.263  -0.815  -0.819  -0.447  -0.838  -0.865  -0.510
117   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
118   P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
119   E        -1.865  -1.950  -1.623  -1.863  -2.018  -1.620  -1.721  -1.757  -1.348
120   D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
121   I        -0.498  -0.321  -0.224  -0.815  -0.525  -0.400  -0.838  -0.558  -0.444
122   W         0.157  -0.057  -0.176   0.649   0.374   0.110   0.171  -0.140  -0.365
123   V        -0.571  -0.502  -0.266  -0.926  -0.817  -0.458  -0.964  -0.865  -0.515
124   R        -2.166  -1.842  -2.029  -1.553  -1.177  -1.482  -1.721  -1.405  -1.492
125   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
126   V        -1.767  -1.529  -1.588  -1.713  -1.384  -1.527  -1.595  -1.325  -1.316
127   N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
128   T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
129   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
130   M         1.024   1.047   1.109   1.210   1.235   1.314   1.054   1.089   1.181
131   E         0.157   0.143  -0.160   0.194   0.183  -0.209   0.171   0.149  -0.338
132   P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
133   G         0.157   0.143  -0.160   0.239   0.234  -0.187   0.171   0.149  -0.338
134   K         1.024   1.047   1.109   1.060   1.095   1.189   1.054   1.089   1.181
135   T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
136   S         1.024   1.047   1.109   0.942   0.983   1.091   1.054   1.089   1.181
137   F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
138   F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
139   Q         1.024   1.047   1.109   1.226   1.254   1.327   1.054   1.089   1.181
140   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
141   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
142   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
143   V         0.157  -0.057  -0.176   0.117  -0.131  -0.323   0.171  -0.140  -0.365
144   P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
145   T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
146   K         1.024   1.047   1.109   1.060   1.095   1.189   1.054   1.089   1.181
147   I         1.024   1.047   1.109   0.978   1.012   1.121   1.054   1.089   1.181
148   A        -0.669  -0.886  -1.000  -0.765  -1.043  -1.156  -0.586  -0.866  -0.997
149   R         1.024   1.047   1.109   1.140   1.175   1.256   1.054   1.089   1.181
150   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
151   T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
152   I         1.024   1.047   1.109   0.978   1.012   1.121   1.054   1.089   1.181
153   E         1.024   1.047   1.109   0.881   0.918   1.041   1.054   1.089   1.181
154   I         1.024   1.047   1.109   0.978   1.012   1.121   1.054   1.089   1.181
155   V        -0.498  -0.502  -0.263  -0.770  -0.767  -0.393  -0.838  -0.865  -0.510
156   S         0.157   0.061  -0.168   0.252   0.142  -0.185   0.171   0.033  -0.352
157   D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
158   V         0.157   0.061  -0.168   0.105   0.008  -0.343   0.171   0.033  -0.352
159   K        -0.669  -0.776  -0.988  -0.256  -0.393  -0.676  -0.586  -0.739  -0.982
160   V        -1.048  -1.161  -1.041  -1.132  -1.334  -1.138  -1.091  -1.255  -1.049
161   V         0.157   0.143  -0.160   0.105   0.112  -0.328   0.171   0.149  -0.338
162   D        -1.767  -1.799  -1.603  -1.583  -1.631  -1.359  -1.595  -1.598  -1.329
163   A        -1.767  -1.763  -1.607  -1.736  -1.742  -1.436  -1.595  -1.577  -1.334
164   G        -1.218  -1.105  -1.032  -1.223  -1.092  -0.937  -1.343  -1.223  -1.040
165   N        -2.414  -2.152  -2.043  -2.406  -2.107  -1.916  -1.974  -1.714  -1.503
166   K        -0.270  -0.073  -0.194  -0.163   0.102  -0.105  -0.460  -0.164  -0.393
167   V         1.024   1.047   1.109   0.819   0.877   0.989   1.054   1.089   1.181
168   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
169   Q        -0.669  -0.391  -0.958  -0.329  -0.011  -0.823  -0.586  -0.252  -0.945
170   S         1.024   1.047   1.109   0.942   0.983   1.091   1.054   1.089   1.181
171   E         1.024   1.047   1.109   0.881   0.918   1.041   1.054   1.089   1.181
172   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
173   S        -0.498  -0.321  -0.224  -0.621  -0.344  -0.245  -0.838  -0.558  -0.444
174   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
175   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
176   N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
177   L        -0.498  -0.321  -0.224  -0.509  -0.219  -0.156  -0.838  -0.558  -0.444
178   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
179   N         0.157   0.270  -0.149   0.399   0.526  -0.048   0.171   0.321  -0.320
180   I         1.024   1.047   1.109   0.978   1.012   1.121   1.054   1.089   1.181
181   S         1.024   1.047   1.109   0.942   0.983   1.091   1.054   1.089   1.181
182   P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
183   F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
184   T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
185   F         0.157   0.315  -0.148   0.506   0.683   0.051   0.171   0.379  -0.317
186   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
187   L        -0.498  -0.321  -0.224  -0.509  -0.219  -0.156  -0.838  -0.558  -0.444
188   T        -1.767  -1.852  -1.612  -1.511  -1.640  -1.386  -1.595  -1.648  -1.338
189   V         0.157   0.061  -0.168   0.117   0.024  -0.311   0.171   0.033  -0.352
190   V        -0.669  -0.956  -1.011  -0.649  -1.053  -1.242  -0.586  -0.950  -1.010
191   Q         0.157  -0.057  -0.176   0.535   0.256   0.013   0.171  -0.140  -0.365
192   V         0.157  -0.057  -0.176   0.117  -0.131  -0.323   0.171  -0.140  -0.365
193   Y         1.024   1.047   1.109   1.191   1.228   1.298   1.054   1.089   1.181
194   D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
195   N        -0.498  -0.493  -0.265  -0.444  -0.457  -0.143  -0.838  -0.850  -0.515
196   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
197   Q        -0.270  -0.408  -0.260  -0.019  -0.278  -0.129  -0.460  -0.704  -0.506
198   V        -0.669  -0.669  -0.980  -0.562  -0.555  -0.979  -0.586  -0.596  -0.972
199   F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
200   P        -0.669  -0.886  -1.000  -0.328  -0.637  -0.893  -0.586  -0.866  -0.997
201   S        -0.669  -0.736  -0.987  -0.493  -0.587  -1.031  -0.586  -0.696  -0.981
202   S        -1.767  -1.759  -1.610  -1.617  -1.684  -1.439  -1.595  -1.601  -1.337
203   I         0.157   0.061  -0.168   0.254   0.132  -0.253   0.171   0.033  -0.352
204   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
205   D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
206   I         0.157  -0.057  -0.176   0.254  -0.029  -0.268   0.171  -0.140  -0.365
207   T        -0.270  -0.408  -0.260  -0.226  -0.499  -0.318  -0.460  -0.704  -0.506
208   D        -0.270  -0.408  -0.260  -0.266  -0.533  -0.366  -0.460  -0.704  -0.506
209   E        -0.498  -0.325  -0.235  -0.728  -0.464  -0.344  -0.838  -0.564  -0.463
210   E        -0.669  -0.956  -1.011  -0.461  -0.823  -0.886  -0.586  -0.950  -1.010
211   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
212   V        -1.218  -1.175  -1.023  -1.362  -1.258  -1.081  -1.343  -1.251  -1.028
213   S        -1.048  -1.169  -1.037  -0.986  -1.178  -1.008  -1.091  -1.242  -1.044
214   H        -0.669  -0.783  -0.991  -0.138  -0.321  -0.784  -0.586  -0.731  -0.986
215   F        -0.669  -0.886  -1.000  -0.333  -0.652  -0.940  -0.586  -0.866  -0.997
216   V        -1.767  -1.907  -1.615  -1.746  -1.950  -1.562  -1.595  -1.709  -1.341
217   S        -0.669  -0.783  -0.991  -0.447  -0.595  -0.928  -0.586  -0.731  -0.986
218   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
219   V        -1.218  -1.246  -1.033  -1.419  -1.446  -1.205  -1.343  -1.326  -1.038
220   S        -1.466  -1.353  -1.061  -1.482  -1.354  -0.956  -1.595  -1.451  -1.070
221   T         0.157  -0.057  -0.176   0.358   0.071  -0.142   0.171  -0.140  -0.365
222   I         0.157   0.324  -0.146   0.254   0.449  -0.212   0.171   0.390  -0.315
223   A        -0.270  -0.378  -0.256  -0.610  -0.776  -0.532  -0.460  -0.653  -0.498
224   S        -1.218  -1.076  -1.025  -1.414  -1.305  -1.064  -1.343  -1.199  -1.032
225   I        -0.669  -0.629  -0.978  -0.455  -0.426  -0.987  -0.586  -0.551  -0.970
226   S         1.024   1.047   1.109   0.942   0.983   1.091   1.054   1.089   1.181
227   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
228   A         0.157  -0.057  -0.176  -0.086  -0.347  -0.492   0.171  -0.140  -0.365
229   I        -1.446  -1.325  -1.565  -1.503  -1.368  -1.690  -1.217  -1.092  -1.293
230   G        -0.498  -0.502  -0.263  -0.653  -0.664  -0.308  -0.838  -0.865  -0.510
231   Y         0.157   0.061  -0.168   0.506   0.394   0.017   0.171   0.033  -0.352
232   P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
233   T         1.024   1.047   1.109   1.060   1.082   1.189   1.054   1.089   1.181
234   L         0.157  -0.057  -0.176   0.198  -0.075  -0.262   0.171  -0.140  -0.365
235   P         0.157  -0.057  -0.176   0.368   0.084  -0.157   0.171  -0.140  -0.365
236   S         0.157   0.143  -0.160   0.190   0.176  -0.340   0.171   0.149  -0.338
237   V         1.024   1.047   1.109   0.819   0.877   0.989   1.054   1.089   1.181
238   G        -1.446  -1.709  -1.607  -1.100  -1.452  -1.362  -1.217  -1.501  -1.332
239   H         1.024   1.047   1.109   1.295   1.323   1.385   1.054   1.089   1.181
240   T        -1.048  -0.900  -0.995  -0.881  -0.672  -0.776  -1.091  -0.884  -0.991
241   L        -1.466  -1.312  -1.052  -1.737  -1.517  -1.148  -1.595  -1.403  -1.059
242   I        -0.498  -0.497  -0.265  -0.758  -0.802  -0.459  -0.838  -0.857  -0.514
243   N         1.024   1.047   1.109   1.093   1.124   1.217   1.054   1.089   1.181
244   N        -1.048  -1.068  -1.036  -0.908  -1.098  -0.984  -1.091  -1.165  -1.043
245   Y         1.024   1.047   1.109   1.191   1.228   1.298   1.054   1.089   1.181
246   K         1.024   1.047   1.109   1.060   1.095   1.189   1.054   1.089   1.181
247   D        -1.048  -0.975  -1.005  -0.803  -0.693  -0.809  -1.091  -0.974  -1.004
248   L        -0.571  -0.502  -0.266  -0.984  -0.878  -0.507  -0.964  -0.865  -0.515
249   L         0.157  -0.057  -0.176   0.176  -0.108  -0.327   0.171  -0.140  -0.365
250   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
251   V        -0.498  -0.388  -0.243  -0.858  -0.674  -0.472  -0.838  -0.670  -0.477
252   A        -0.571  -0.496  -0.265  -1.097  -0.963  -0.592  -0.964  -0.855  -0.513
253   I        -0.669  -0.695  -0.982  -0.455  -0.531  -0.993  -0.586  -0.652  -0.975
254   A         0.157   0.061  -0.168  -0.094  -0.204  -0.502   0.171   0.033  -0.352
255   A        -1.369  -1.166  -1.044  -1.500  -1.182  -1.116  -1.469  -1.216  -1.051
256   S        -1.369  -1.300  -1.054  -1.411  -1.371  -1.051  -1.469  -1.399  -1.062
257   Y         0.157   0.061  -0.168   0.489   0.372  -0.030   0.171   0.033  -0.352
258   H        -1.767  -1.593  -1.594  -1.364  -1.181  -1.229  -1.595  -1.393  -1.321
259   Y        -1.218  -1.235  -1.035  -0.929  -0.951  -0.680  -1.343  -1.338  -1.042
260   P        -0.571  -0.496  -0.265  -0.804  -0.711  -0.359  -0.964  -0.855  -0.513
261   E        -0.571  -0.496  -0.265  -0.915  -0.800  -0.446  -0.964  -0.855  -0.513
262   I        -1.218  -1.282  -1.040  -1.252  -1.320  -0.984  -1.343  -1.377  -1.047
263   E         1.024   1.047   1.109   0.881   0.918   1.041   1.054   1.089   1.181
264   D        -1.865  -1.825  -1.610  -2.003  -1.916  -1.535  -1.721  -1.663  -1.337
265   L        -1.767  -1.727  -1.606  -1.661  -1.638  -1.490  -1.595  -1.557  -1.333
266   V        -0.669  -0.383  -0.957  -0.361  -0.026  -0.861  -0.586  -0.242  -0.945
267   D         0.157  -0.057  -0.176   0.288  -0.009  -0.299   0.171  -0.140  -0.365
268   R         0.157  -0.057  -0.176   0.455   0.191  -0.034   0.171  -0.140  -0.365
269   I        -0.498  -0.455  -0.259  -0.715  -0.676  -0.393  -0.838  -0.784  -0.504
270   E        -0.498  -0.321  -0.224  -1.045  -0.764  -0.591  -0.838  -0.558  -0.444
271   N         0.157  -0.057  -0.176   0.399   0.129  -0.094   0.171  -0.140  -0.365
272   P         1.024   1.047   1.109   1.081   1.114   1.207   1.054   1.089   1.181
273   E        -1.048  -1.092  -1.021  -1.026  -1.084  -1.014  -1.091  -1.121  -1.024
274   K        -0.669  -0.383  -0.957  -0.737  -0.411  -1.043  -0.586  -0.242  -0.945
275   Y         0.157  -0.057  -0.176   0.506   0.243   0.004   0.171  -0.140  -0.365
276   A         0.157  -0.057  -0.176  -0.103  -0.372  -0.542   0.171  -0.140  -0.365
277   A        -1.218  -1.293  -1.037  -1.603  -1.689  -1.289  -1.343  -1.392  -1.045
278   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
279   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
280   P         0.157  -0.057  -0.176   0.331   0.024  -0.265   0.171  -0.140  -0.365
281   A        -0.669  -0.736  -0.987  -0.783  -0.870  -1.183  -0.586  -0.696  -0.981
282   A         1.024   1.047   1.109   0.624   0.670   0.828   1.054   1.089   1.181
283   T        -0.669  -0.629  -0.977  -0.765  -0.730  -1.128  -0.586  -0.550  -0.969
284   S        -0.669  -0.629  -0.977  -0.765  -0.722  -1.128  -0.586  -0.550  -0.969
285   A        -1.048  -0.998  -1.014  -1.326  -1.244  -1.249  -1.091  -1.005  -1.016
286   A        -1.403  -1.321  -1.052  -1.677  -1.565  -1.217  -1.530  -1.423  -1.061
287   S        -1.218  -1.175  -1.023  -1.380  -1.305  -1.151  -1.343  -1.251  -1.028
288   G        -2.016  -1.973  -1.622  -2.293  -2.242  -1.713  -1.848  -1.771  -1.347
289   D        -2.016  -1.915  -1.618  -2.173  -2.042  -1.581  -1.848  -1.717  -1.344
290   A        -0.571  -0.498  -0.264  -1.145  -1.026  -0.631  -0.964  -0.859  -0.513
291   A        -0.270  -0.078  -0.191  -0.673  -0.393  -0.539  -0.460  -0.173  -0.390
292   P        -1.865  -1.791  -1.603  -1.965  -1.845  -1.596  -1.721  -1.626  -1.331
293   A        -0.669  -0.783  -0.991  -0.739  -0.875  -1.086  -0.586  -0.731  -0.986
294   E        -1.287  -1.066  -1.025  -1.663  -1.400  -1.224  -1.418  -1.152  -1.029
295   E         0.081   0.078  -0.169   0.021   0.016  -0.416   0.065   0.057  -0.353
296   A        -1.048  -0.916  -1.015  -1.309  -1.151  -1.201  -1.091  -0.938  -1.018
297   A        -0.669  -0.629  -0.978  -0.739  -0.700  -1.072  -0.586  -0.551  -0.970
298   A        -0.498  -0.466  -0.264  -1.045  -1.005  -0.644  -0.838  -0.804  -0.512
299   E         0.157   0.361  -0.144   0.129   0.373  -0.357   0.171   0.437  -0.311
300   E        -0.270  -0.162  -0.219  -0.368  -0.220  -0.320  -0.460  -0.302  -0.437
301   E         0.157   0.061  -0.168   0.191   0.080  -0.231   0.171   0.033  -0.352
302   E         0.157   0.324  -0.146   0.188   0.377  -0.204   0.171   0.390  -0.315
303   E         0.157   0.143  -0.160   0.174   0.161  -0.264   0.171   0.149  -0.338
304   S         0.157   0.143  -0.160   0.226   0.216  -0.241   0.171   0.149  -0.338
305   D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   D        -0.669  -0.776  -0.988  -0.380  -0.549  -0.926  -0.586  -0.739  -0.982
308   D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
309   M         0.157   0.061  -0.168   0.501   0.372  -0.033   0.171   0.033  -0.352
310   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
311   F         0.157   0.270  -0.149   0.431   0.553   0.021   0.171   0.321  -0.320
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   G         1.024   1.047   1.109   0.932   0.976   1.083   1.054   1.089   1.181
314   L         1.024   1.047   1.109   0.900   0.933   1.057   1.054   1.089   1.181
315   F         1.024   1.047   1.109   1.100   1.132   1.223   1.054   1.089   1.181
316   D         1.024   1.047   1.109   1.038   1.080   1.171   1.054   1.089   1.181
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P05317
Output conservation file - output/P05317
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
