1     M         1.180   1.198   1.264   1.325   1.347   1.441   1.275   1.298   1.400
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    S        -0.290  -0.331  -0.403  -0.334  -0.397  -0.502  -0.408  -0.478  -0.588
21    T        -0.925  -0.929  -0.892  -0.989  -1.025  -1.016  -0.969  -0.975  -0.912
22    T        -1.077  -1.073  -0.929  -1.064  -1.061  -0.864  -1.149  -1.140  -0.952
23    A        -0.608  -0.552  -0.463  -0.933  -0.861  -0.678  -0.879  -0.803  -0.675
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    S        -1.352  -1.306  -1.250  -1.480  -1.433  -1.319  -1.250  -1.200  -1.085
29    T        -1.352  -1.408  -1.263  -1.441  -1.530  -1.316  -1.250  -1.284  -1.096
30    P        -0.947  -0.841  -0.875  -1.076  -0.947  -0.917  -1.039  -0.929  -0.901
31    S        -1.169  -1.126  -1.216  -1.047  -1.001  -1.105  -1.039  -0.990  -1.050
32    S        -1.401  -1.342  -1.256  -1.443  -1.326  -1.224  -1.301  -1.228  -1.091
33    L        -0.258  -0.099  -0.364  -0.125   0.106  -0.341  -0.387  -0.164  -0.535
34    R         1.180   1.198   1.264   1.308   1.325   1.425   1.275   1.298   1.400
35    H         1.180   1.198   1.264   1.338   1.365   1.452   1.275   1.298   1.400
36    L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
37    I        -0.618  -0.639  -0.478  -0.927  -0.973  -0.722  -0.886  -0.909  -0.694
38    S         0.282   0.366   0.246   0.156   0.280   0.087   0.111   0.249  -0.010
39    I         0.589   0.644   0.339   0.615   0.696   0.280   0.610   0.688   0.164
40    K        -1.923  -1.952  -1.821  -1.749  -1.802  -1.628  -1.468  -1.478  -1.297
41    D        -0.258  -0.252  -0.396  -0.206  -0.206  -0.418  -0.387  -0.395  -0.587
42    L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
43    S         0.021   0.122  -0.299   0.055   0.181  -0.403   0.028   0.164  -0.439
44    D        -1.401  -1.409  -1.277  -1.287  -1.272  -1.090  -1.301  -1.292  -1.109
45    E        -1.662  -1.718  -1.558  -1.560  -1.651  -1.422  -1.385  -1.409  -1.209
46    E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
47    F        -0.408  -0.453  -0.417  -0.524  -0.569  -0.545  -0.637  -0.676  -0.617
48    R        -2.021  -1.954  -1.808  -1.976  -1.903  -1.674  -1.551  -1.486  -1.290
49    I        -0.618  -0.564  -0.466  -0.947  -0.860  -0.710  -0.886  -0.821  -0.679
50    L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
51    V         0.282   0.275   0.214   0.180   0.158   0.026   0.111   0.091  -0.071
52    Q        -1.662  -1.603  -1.542  -1.511  -1.442  -1.349  -1.385  -1.319  -1.197
53    R        -0.767  -0.790  -0.857  -0.567  -0.587  -0.722  -0.803  -0.814  -0.875
54    A         0.021  -0.071  -0.332   0.041  -0.089  -0.464   0.028  -0.101  -0.486
55    Q        -1.662  -1.581  -1.554  -1.542  -1.481  -1.373  -1.385  -1.314  -1.206
56    H        -2.021  -1.959  -1.813  -1.746  -1.710  -1.469  -1.551  -1.488  -1.293
57    F        -0.767  -0.867  -0.880  -0.601  -0.737  -0.794  -0.803  -0.916  -0.903
58    K         1.180   1.198   1.264   1.120   1.148   1.252   1.275   1.298   1.400
59    N        -0.879  -0.804  -0.868  -0.907  -0.806  -0.868  -0.969  -0.897  -0.893
60    V        -1.760  -1.664  -1.571  -1.716  -1.594  -1.434  -1.468  -1.375  -1.219
61    F        -1.401  -1.437  -1.276  -1.285  -1.310  -1.105  -1.301  -1.313  -1.108
62    K         0.589   0.644   0.339   0.633   0.704   0.317   0.610   0.688   0.164
63    A        -0.506  -0.563  -0.471  -0.705  -0.805  -0.672  -0.720  -0.801  -0.685
64    N        -1.238  -1.241  -1.232  -1.106  -1.119  -1.136  -1.135  -1.125  -1.068
65    K        -1.401  -1.321  -1.263  -1.373  -1.245  -1.176  -1.301  -1.224  -1.097
66    T        -2.282  -2.251  -2.044  -2.056  -2.035  -1.755  -1.634  -1.594  -1.360
67    N        -1.760  -1.691  -1.559  -1.826  -1.725  -1.522  -1.468  -1.398  -1.211
68    D        -1.320  -1.348  -1.258  -1.151  -1.194  -1.069  -1.198  -1.221  -1.089
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    F        -0.925  -1.009  -0.922  -0.790  -0.911  -0.803  -0.969  -1.063  -0.945
74    Q        -1.238  -1.341  -1.257  -1.070  -1.206  -1.139  -1.135  -1.216  -1.090
75    S        -1.238  -1.297  -1.248  -1.205  -1.290  -1.255  -1.135  -1.182  -1.083
76    N        -0.618  -0.615  -0.471  -0.736  -0.739  -0.544  -0.886  -0.875  -0.685
77    H        -0.519  -0.715  -0.850  -0.153  -0.423  -0.691  -0.470  -0.711  -0.864
78    L        -1.662  -1.724  -1.570  -1.577  -1.664  -1.434  -1.385  -1.415  -1.217
79    K         0.021  -0.071  -0.332   0.111  -0.004  -0.405   0.028  -0.101  -0.486
80    L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
81    L        -0.258  -0.400  -0.420  -0.373  -0.600  -0.652  -0.387  -0.588  -0.618
82    G         0.589   0.505   0.326   0.720   0.606   0.318   0.610   0.478   0.139
83    R        -0.408  -0.468  -0.418  -0.462  -0.528  -0.430  -0.637  -0.700  -0.621
84    T        -0.767  -0.761  -0.854  -0.704  -0.673  -0.861  -0.803  -0.778  -0.871
85    I         0.016   0.074   0.175  -0.315  -0.210  -0.053  -0.387  -0.285  -0.147
86    A         0.589   0.589   0.333   0.567   0.564   0.252   0.610   0.607   0.152
87    L         0.101   0.065   0.164  -0.092  -0.149   0.017  -0.221  -0.302  -0.171
88    I        -0.408  -0.461  -0.413  -0.588  -0.610  -0.541  -0.637  -0.675  -0.610
89    F         1.180   1.198   1.264   1.227   1.258   1.350   1.275   1.298   1.400
90    T         0.016   0.084   0.178  -0.293  -0.182  -0.032  -0.387  -0.265  -0.142
91    K         1.180   1.198   1.264   1.120   1.148   1.252   1.275   1.298   1.400
92    R         1.180   1.198   1.264   1.308   1.325   1.425   1.275   1.298   1.400
93    S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
94    T         1.180   1.198   1.264   1.214   1.238   1.338   1.275   1.298   1.400
95    R         1.180   1.198   1.264   1.308   1.325   1.425   1.275   1.298   1.400
96    T         1.180   1.198   1.264   1.214   1.238   1.338   1.275   1.298   1.400
97    R         1.180   1.198   1.264   1.308   1.325   1.425   1.275   1.298   1.400
98    I         0.101   0.053   0.163  -0.146  -0.248  -0.079  -0.221  -0.326  -0.171
99    S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
100   T         0.589   0.505   0.326   0.704   0.598   0.316   0.610   0.478   0.139
101   E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
102   G         0.021  -0.182  -0.348   0.202  -0.094  -0.401   0.028  -0.255  -0.510
103   A         1.180   1.198   1.264   1.051   1.069   1.189   1.275   1.298   1.400
104   A        -0.408  -0.391  -0.427  -0.662  -0.679  -0.675  -0.637  -0.642  -0.632
105   T        -0.506  -0.443  -0.432  -0.740  -0.655  -0.648  -0.720  -0.631  -0.631
106   F        -0.519  -0.671  -0.833  -0.216  -0.422  -0.649  -0.470  -0.661  -0.844
107   F        -0.258  -0.413  -0.419  -0.192  -0.417  -0.460  -0.387  -0.599  -0.616
108   G         1.180   1.198   1.264   1.237   1.254   1.359   1.275   1.298   1.400
109   A         0.016   0.030   0.161  -0.292  -0.267  -0.041  -0.387  -0.370  -0.175
110   Q        -0.258  -0.385  -0.411  -0.074  -0.251  -0.313  -0.387  -0.565  -0.607
111   P         0.282   0.251   0.209   0.360   0.289   0.151   0.111   0.047  -0.081
112   M         1.180   1.198   1.264   1.325   1.347   1.441   1.275   1.298   1.400
113   F         1.180   1.198   1.264   1.227   1.258   1.350   1.275   1.298   1.400
114   L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
115   G         1.180   1.198   1.264   1.237   1.254   1.359   1.275   1.298   1.400
116   K         1.180   1.198   1.264   1.120   1.148   1.252   1.275   1.298   1.400
117   E         0.101   0.183   0.200  -0.074   0.073   0.061  -0.221  -0.076  -0.100
118   D         1.180   1.198   1.264   1.170   1.198   1.298   1.275   1.298   1.400
119   I         1.180   1.198   1.264   1.113   1.151   1.246   1.275   1.298   1.400
120   Q         1.180   1.198   1.264   1.279   1.305   1.398   1.275   1.298   1.400
121   L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
122   G         1.180   1.198   1.264   1.237   1.254   1.359   1.275   1.298   1.400
123   V         1.180   1.198   1.264   1.123   1.138   1.255   1.275   1.298   1.400
124   N         1.180   1.198   1.264   1.219   1.252   1.343   1.275   1.298   1.400
125   E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
126   S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
127   F        -1.041  -0.953  -0.907  -1.126  -1.021  -0.900  -1.135  -1.035  -0.931
128   Y         1.180   1.198   1.264   1.387   1.412   1.498   1.275   1.298   1.400
129   D         1.180   1.198   1.264   1.170   1.198   1.298   1.275   1.298   1.400
130   T         1.180   1.198   1.264   1.214   1.238   1.338   1.275   1.298   1.400
131   T        -0.506  -0.559  -0.471  -0.648  -0.777  -0.677  -0.720  -0.801  -0.685
132   K         0.282   0.302   0.223   0.232   0.262   0.131   0.111   0.139  -0.055
133   V         1.180   1.198   1.264   1.123   1.138   1.255   1.275   1.298   1.400
134   V         0.016   0.066   0.169  -0.317  -0.222  -0.068  -0.387  -0.301  -0.160
135   S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
136   S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
137   M         1.180   1.198   1.264   1.325   1.347   1.441   1.275   1.298   1.400
138   V         0.016   0.050   0.164  -0.234  -0.182  -0.004  -0.387  -0.332  -0.170
139   S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
140   C         0.589   0.505   0.326   0.888   0.788   0.501   0.610   0.478   0.139
141   I         0.589   0.465   0.322   0.629   0.496   0.290   0.610   0.414   0.131
142   F         0.101   0.053   0.163  -0.040  -0.157   0.003  -0.221  -0.326  -0.171
143   A         1.180   1.198   1.264   1.051   1.069   1.189   1.275   1.298   1.400
144   R         1.180   1.198   1.264   1.308   1.325   1.425   1.275   1.298   1.400
145   V         1.180   1.198   1.264   1.123   1.138   1.255   1.275   1.298   1.400
146   N         0.282   0.208   0.205   0.308   0.190   0.146   0.111  -0.031  -0.089
147   K        -1.028  -1.043  -1.204  -0.846  -0.872  -1.119  -0.886  -0.905  -1.038
148   H         0.589   0.505   0.326   0.860   0.768   0.510   0.610   0.478   0.139
149   E        -0.977  -0.925  -0.905  -1.010  -0.974  -0.959  -1.052  -1.005  -0.929
150   D         0.101   0.135   0.183  -0.074  -0.015   0.028  -0.221  -0.167  -0.132
151   I         0.282   0.168   0.201   0.173  -0.022  -0.004   0.111  -0.105  -0.098
152   L        -0.258  -0.309  -0.404  -0.360  -0.495  -0.583  -0.387  -0.498  -0.596
153   A        -1.028  -0.926  -1.195  -0.837  -0.695  -1.140  -0.886  -0.776  -1.030
154   F         0.589   0.686   0.344   0.571   0.689   0.252   0.610   0.749   0.173
155   C        -0.408  -0.433  -0.425  -0.400  -0.487  -0.490  -0.637  -0.678  -0.630
156   K        -1.238  -1.251  -1.232  -1.144  -1.148  -1.134  -1.135  -1.130  -1.068
157   D        -0.455  -0.442  -0.416  -0.506  -0.480  -0.440  -0.720  -0.693  -0.620
158   S         0.589   0.505   0.326   0.548   0.439   0.162   0.610   0.478   0.139
159   S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
160   V         0.589   0.505   0.326   0.647   0.544   0.325   0.610   0.478   0.139
161   P         1.180   1.198   1.264   1.324   1.341   1.439   1.275   1.298   1.400
162   I         0.101   0.053   0.163  -0.146  -0.248  -0.079  -0.221  -0.326  -0.171
163   I         0.589   0.674   0.344   0.603   0.720   0.257   0.610   0.732   0.172
164   N         1.180   1.198   1.264   1.219   1.252   1.343   1.275   1.298   1.400
165   S        -0.408  -0.480  -0.426  -0.655  -0.766  -0.648  -0.637  -0.721  -0.631
166   L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
167   C         0.589   0.465   0.322   0.868   0.706   0.440   0.610   0.414   0.131
168   D         0.589   0.589   0.333   0.665   0.673   0.303   0.610   0.607   0.152
169   K        -1.238  -1.281  -1.238  -1.110  -1.181  -1.078  -1.135  -1.173  -1.075
170   F         0.016   0.031   0.159  -0.030  -0.015   0.167  -0.387  -0.369  -0.179
171   H         1.180   1.198   1.264   1.338   1.365   1.452   1.275   1.298   1.400
172   P         1.180   1.198   1.264   1.324   1.341   1.439   1.275   1.298   1.400
173   L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
174   Q         1.180   1.198   1.264   1.279   1.305   1.398   1.275   1.298   1.400
175   A         1.180   1.198   1.264   1.051   1.069   1.189   1.275   1.298   1.400
176   I         0.589   0.505   0.326   0.596   0.503   0.208   0.610   0.478   0.139
177   C        -0.682  -0.636  -0.478  -0.831  -0.797  -0.549  -0.969  -0.905  -0.694
178   D         1.180   1.198   1.264   1.170   1.198   1.298   1.275   1.298   1.400
179   L        -1.041  -1.069  -0.907  -1.126  -1.144  -0.917  -1.135  -1.139  -0.933
180   L         0.021  -0.108  -0.336   0.071  -0.087  -0.425   0.028  -0.154  -0.492
181   T         0.589   0.627   0.340   0.697   0.747   0.324   0.610   0.664   0.166
182   I         1.180   1.198   1.264   1.113   1.151   1.246   1.275   1.298   1.400
183   I         0.021  -0.019  -0.321   0.132   0.090  -0.337   0.028  -0.040  -0.470
184   E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
185   N        -1.760  -1.655  -1.564  -1.639  -1.528  -1.374  -1.468  -1.374  -1.214
186   F         0.282   0.379   0.259   0.270   0.427   0.182   0.111   0.271   0.014
187   N        -1.401  -1.444  -1.270  -1.379  -1.449  -1.214  -1.301  -1.312  -1.102
188   I        -2.021  -2.005  -1.818  -1.774  -1.771  -1.540  -1.551  -1.520  -1.296
189   S        -1.465  -1.395  -1.290  -1.501  -1.397  -1.273  -1.343  -1.273  -1.118
190   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   N        -2.021  -1.978  -1.812  -1.969  -1.904  -1.692  -1.551  -1.499  -1.292
200   S        -1.401  -1.372  -1.264  -1.456  -1.407  -1.258  -1.301  -1.263  -1.097
201   K        -0.408  -0.341  -0.399  -0.470  -0.339  -0.429  -0.637  -0.521  -0.588
202   L         0.589   0.465   0.322   0.584   0.439   0.250   0.610   0.414   0.131
203   K         1.180   1.198   1.264   1.120   1.148   1.252   1.275   1.298   1.400
204   M        -0.977  -0.931  -0.905  -1.086  -1.056  -0.976  -1.052  -1.009  -0.929
205   A         0.282   0.375   0.239   0.138   0.268   0.059   0.111   0.265  -0.023
206   W         1.180   1.198   1.264   1.426   1.448   1.534   1.275   1.298   1.400
207   I         0.016   0.030   0.161  -0.317  -0.297  -0.083  -0.387  -0.370  -0.175
208   G         1.180   1.198   1.264   1.237   1.254   1.359   1.275   1.298   1.400
209   D         1.180   1.198   1.264   1.170   1.198   1.298   1.275   1.298   1.400
210   A         0.101   0.100   0.170  -0.230  -0.250  -0.146  -0.221  -0.233  -0.158
211   N         1.180   1.198   1.264   1.219   1.252   1.343   1.275   1.298   1.400
212   N         1.180   1.198   1.264   1.219   1.252   1.343   1.275   1.298   1.400
213   V         1.180   1.198   1.264   1.123   1.138   1.255   1.275   1.298   1.400
214   I         0.101   0.053   0.163  -0.171  -0.275  -0.114  -0.221  -0.326  -0.171
215   N        -0.258  -0.413  -0.419  -0.130  -0.334  -0.365  -0.387  -0.599  -0.616
216   D         1.180   1.198   1.264   1.170   1.198   1.298   1.275   1.298   1.400
217   M         0.016   0.043   0.163  -0.219  -0.179   0.017  -0.387  -0.345  -0.172
218   C        -0.767  -0.722  -0.842  -0.787  -0.722  -0.837  -0.803  -0.740  -0.857
219   I         0.589   0.465   0.322   0.615   0.475   0.251   0.610   0.414   0.131
220   A         1.180   1.198   1.264   1.051   1.069   1.189   1.275   1.298   1.400
221   C        -0.879  -0.885  -0.866  -0.824  -0.817  -0.816  -0.969  -0.960  -0.890
222   L         0.021  -0.182  -0.348   0.039  -0.244  -0.526   0.028  -0.255  -0.510
223   K         0.021  -0.058  -0.326   0.159   0.063  -0.284   0.028  -0.089  -0.478
224   F        -0.767  -0.754  -0.853  -0.844  -0.834  -0.974  -0.803  -0.785  -0.872
225   G         1.180   1.198   1.264   1.237   1.254   1.359   1.275   1.298   1.400
226   I        -0.258  -0.321  -0.387  -0.251  -0.322  -0.437  -0.387  -0.456  -0.571
227   S        -1.041  -1.044  -0.905  -1.161  -1.129  -0.917  -1.135  -1.115  -0.930
228   V         0.021  -0.182  -0.348   0.117  -0.162  -0.422   0.028  -0.255  -0.510
229   S        -0.408  -0.411  -0.413  -0.659  -0.673  -0.637  -0.637  -0.639  -0.615
230   I        -0.408  -0.433  -0.425  -0.609  -0.661  -0.635  -0.637  -0.678  -0.630
231   S         0.101   0.190   0.199  -0.230  -0.078  -0.087  -0.221  -0.064  -0.102
232   T        -0.879  -0.988  -0.890  -0.950  -1.092  -0.970  -0.969  -1.056  -0.914
233   P         1.180   1.198   1.264   1.324   1.341   1.439   1.275   1.298   1.400
234   P        -0.879  -0.897  -0.876  -0.875  -0.910  -0.860  -0.969  -0.962  -0.897
235   G        -0.879  -0.854  -0.875  -0.887  -0.854  -0.885  -0.969  -0.934  -0.900
236   I        -0.258  -0.400  -0.420  -0.230  -0.417  -0.452  -0.387  -0.588  -0.618
237   E        -1.499  -1.579  -1.547  -1.232  -1.352  -1.324  -1.218  -1.288  -1.199
238   M        -1.401  -1.391  -1.276  -1.353  -1.362  -1.204  -1.301  -1.280  -1.107
239   D        -0.519  -0.715  -0.850  -0.296  -0.551  -0.767  -0.470  -0.711  -0.864
240   S        -1.401  -1.354  -1.271  -1.384  -1.329  -1.164  -1.301  -1.251  -1.104
241   D        -0.767  -0.798  -0.855  -0.703  -0.722  -0.843  -0.803  -0.824  -0.874
242   I        -0.258  -0.303  -0.384  -0.285  -0.309  -0.457  -0.387  -0.430  -0.565
243   V        -2.282  -2.256  -2.040  -2.121  -2.131  -1.791  -1.634  -1.597  -1.358
244   D        -1.662  -1.578  -1.540  -1.496  -1.367  -1.360  -1.385  -1.297  -1.195
245   E        -0.977  -0.846  -0.882  -1.150  -0.917  -1.016  -1.052  -0.884  -0.904
246   A        -1.028  -1.144  -1.230  -0.893  -1.082  -1.168  -0.886  -1.013  -1.063
247   K        -1.662  -1.577  -1.546  -1.572  -1.441  -1.429  -1.385  -1.297  -1.199
248   K        -1.238  -1.317  -1.252  -1.199  -1.330  -1.224  -1.135  -1.206  -1.087
249   V        -1.140  -1.112  -0.942  -1.457  -1.421  -1.160  -1.218  -1.180  -0.965
250   A         0.589   0.658   0.343   0.575   0.650   0.288   0.610   0.709   0.171
251   E        -1.401  -1.390  -1.264  -1.533  -1.496  -1.320  -1.301  -1.275  -1.098
252   R        -1.499  -1.405  -1.521  -1.220  -1.102  -1.270  -1.218  -1.126  -1.178
253   N        -1.499  -1.495  -1.532  -1.277  -1.290  -1.414  -1.218  -1.210  -1.187
254   G        -0.408  -0.451  -0.406  -0.447  -0.494  -0.453  -0.637  -0.660  -0.602
255   A        -2.021  -2.003  -1.815  -2.024  -2.034  -1.708  -1.551  -1.519  -1.294
256   T        -1.238  -1.202  -1.226  -1.099  -1.041  -1.074  -1.135  -1.092  -1.062
257   F         0.021  -0.044  -0.321   0.225   0.144  -0.282   0.028  -0.072  -0.470
258   E        -1.028  -1.043  -1.204  -0.827  -0.861  -1.132  -0.886  -0.905  -1.038
259   L        -1.238  -1.168  -1.235  -1.202  -1.120  -1.183  -1.135  -1.067  -1.072
260   T        -0.879  -0.920  -0.881  -0.912  -0.981  -0.901  -0.969  -1.001  -0.906
261   H        -0.879  -0.953  -0.885  -0.746  -0.844  -0.761  -0.969  -1.030  -0.910
262   D        -0.258  -0.328  -0.386  -0.235  -0.314  -0.437  -0.387  -0.467  -0.568
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   S         0.101   0.198   0.214   0.024   0.199   0.170  -0.221  -0.049  -0.071
266   L        -1.923  -1.815  -1.787  -1.834  -1.672  -1.688  -1.468  -1.371  -1.274
267   K        -1.662  -1.604  -1.552  -1.618  -1.550  -1.467  -1.385  -1.332  -1.205
268   A         1.180   1.198   1.264   1.051   1.069   1.189   1.275   1.298   1.400
269   S        -1.401  -1.250  -1.261  -1.515  -1.284  -1.271  -1.301  -1.142  -1.093
270   T        -1.401  -1.256  -1.261  -1.416  -1.198  -1.210  -1.301  -1.145  -1.093
271   N        -0.618  -0.580  -0.470  -0.747  -0.691  -0.532  -0.886  -0.837  -0.684
272   A         0.589   0.589   0.333   0.534   0.530   0.165   0.610   0.607   0.152
273   N        -0.408  -0.391  -0.427  -0.439  -0.448  -0.437  -0.637  -0.642  -0.632
274   I         0.016   0.050   0.163  -0.317  -0.254  -0.079  -0.387  -0.331  -0.171
275   L        -0.618  -0.602  -0.478  -0.947  -0.919  -0.730  -0.886  -0.859  -0.695
276   V         1.180   1.198   1.264   1.123   1.138   1.255   1.275   1.298   1.400
277   T         1.180   1.198   1.264   1.214   1.238   1.338   1.275   1.298   1.400
278   D         1.180   1.198   1.264   1.170   1.198   1.298   1.275   1.298   1.400
279   T         1.180   1.198   1.264   1.214   1.238   1.338   1.275   1.298   1.400
280   F         0.101   0.198   0.214   0.187   0.358   0.325  -0.221  -0.049  -0.071
281   V         0.016   0.043   0.163  -0.317  -0.269  -0.080  -0.387  -0.345  -0.172
282   S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
283   M         1.180   1.198   1.264   1.325   1.347   1.441   1.275   1.298   1.400
284   G         1.180   1.198   1.264   1.237   1.254   1.359   1.275   1.298   1.400
285   E         0.016   0.031   0.162  -0.174  -0.138   0.062  -0.387  -0.368  -0.174
286   E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
287   F        -1.041  -0.953  -0.907  -1.243  -1.136  -1.041  -1.135  -1.035  -0.931
288   A        -0.408  -0.270  -0.391  -0.559  -0.335  -0.484  -0.637  -0.440  -0.577
289   K         0.589   0.465   0.322   0.621   0.472   0.257   0.610   0.414   0.131
290   Q        -0.408  -0.330  -0.403  -0.436  -0.327  -0.443  -0.637  -0.543  -0.600
291   A        -1.028  -1.182  -1.233  -0.890  -1.101  -1.166  -0.886  -1.049  -1.066
292   K         0.282   0.168   0.201   0.232   0.053   0.096   0.111  -0.105  -0.098
293   L         0.282   0.312   0.225   0.187   0.231   0.101   0.111   0.156  -0.051
294   K        -0.519  -0.420  -0.794  -0.353  -0.223  -0.737  -0.470  -0.347  -0.798
295   Q         0.589   0.465   0.322   0.760   0.598   0.342   0.610   0.414   0.131
296   F         1.180   1.198   1.264   1.227   1.258   1.350   1.275   1.298   1.400
297   K        -1.662  -1.583  -1.539  -1.583  -1.477  -1.401  -1.385  -1.300  -1.195
298   G         0.589   0.627   0.340   0.733   0.775   0.376   0.610   0.664   0.166
299   F         0.101   0.151   0.187   0.080   0.164   0.199  -0.221  -0.136  -0.124
300   Q         1.180   1.198   1.264   1.279   1.305   1.398   1.275   1.298   1.400
301   I         0.101   0.098   0.169  -0.146  -0.155  -0.067  -0.221  -0.237  -0.159
302   N        -0.258  -0.107  -0.362  -0.198   0.025  -0.384  -0.387  -0.168  -0.533
303   Q        -1.499  -1.576  -1.544  -1.184  -1.306  -1.338  -1.218  -1.285  -1.197
304   E         0.021   0.094  -0.306   0.168   0.265  -0.297   0.028   0.126  -0.449
305   L        -0.767  -0.736  -0.846  -0.722  -0.679  -0.804  -0.803  -0.752  -0.863
306   V        -1.760  -1.725  -1.564  -1.634  -1.596  -1.350  -1.468  -1.421  -1.214
307   S         0.016   0.031   0.161  -0.356  -0.332  -0.115  -0.387  -0.370  -0.176
308   V        -1.041  -1.006  -0.913  -1.165  -1.116  -0.922  -1.135  -1.092  -0.938
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   A         0.282   0.355   0.253   0.111   0.213   0.042   0.111   0.230   0.002
312   D        -1.401  -1.248  -1.261  -1.517  -1.270  -1.308  -1.301  -1.141  -1.094
313   P         0.101   0.166   0.203   0.024   0.137   0.144  -0.221  -0.108  -0.094
314   N        -1.238  -1.355  -1.258  -1.106  -1.272  -1.164  -1.135  -1.231  -1.091
315   Y        -0.767  -0.713  -0.848  -0.345  -0.255  -0.476  -0.803  -0.720  -0.864
316   K         0.589   0.627   0.340   0.633   0.685   0.318   0.610   0.664   0.166
317   F         1.180   1.198   1.264   1.227   1.258   1.350   1.275   1.298   1.400
318   M         1.180   1.198   1.264   1.325   1.347   1.441   1.275   1.298   1.400
319   H         1.180   1.198   1.264   1.338   1.365   1.452   1.275   1.298   1.400
320   C         1.180   1.198   1.264   1.384   1.411   1.495   1.275   1.298   1.400
321   L         1.180   1.198   1.264   1.068   1.094   1.204   1.275   1.298   1.400
322   P         1.180   1.198   1.264   1.324   1.341   1.439   1.275   1.298   1.400
323   R         1.180   1.198   1.264   1.308   1.325   1.425   1.275   1.298   1.400
324   H         1.180   1.198   1.264   1.338   1.365   1.452   1.275   1.298   1.400
325   Q        -0.879  -0.810  -0.880  -0.728  -0.649  -0.721  -0.969  -0.901  -0.905
326   E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
327   E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
328   V         1.180   1.198   1.264   1.123   1.138   1.255   1.275   1.298   1.400
329   S        -1.140  -1.082  -0.928  -1.391  -1.303  -1.069  -1.218  -1.148  -0.952
330   D         0.589   0.679   0.343   0.665   0.778   0.320   0.610   0.739   0.171
331   D        -0.455  -0.429  -0.413  -0.592  -0.534  -0.474  -0.720  -0.671  -0.615
332   V         0.282   0.345   0.234   0.180   0.270   0.065   0.111   0.214  -0.033
333   F         1.180   1.198   1.264   1.227   1.258   1.350   1.275   1.298   1.400
334   Y         1.180   1.198   1.264   1.387   1.412   1.498   1.275   1.298   1.400
335   G         0.016   0.052   0.166  -0.251  -0.189  -0.016  -0.387  -0.327  -0.166
336   E        -0.977  -1.015  -0.902  -1.024  -1.050  -0.906  -1.052  -1.074  -0.927
337   H        -0.767  -0.807  -0.852  -0.553  -0.583  -0.653  -0.803  -0.829  -0.868
338   S         1.180   1.198   1.264   1.068   1.092   1.204   1.275   1.298   1.400
339   I        -0.455  -0.368  -0.415  -0.735  -0.606  -0.631  -0.720  -0.610  -0.616
340   V         1.180   1.198   1.264   1.123   1.138   1.255   1.275   1.298   1.400
341   F         1.180   1.198   1.264   1.227   1.258   1.350   1.275   1.298   1.400
342   E        -0.767  -0.844  -0.879  -0.633  -0.745  -0.778  -0.803  -0.904  -0.901
343   E         1.180   1.198   1.264   1.165   1.193   1.293   1.275   1.298   1.400
344   A         0.589   0.465   0.322   0.567   0.413   0.235   0.610   0.414   0.131
345   E         0.589   0.465   0.322   0.654   0.500   0.264   0.610   0.414   0.131
346   N         1.180   1.198   1.264   1.202   1.230   1.328   1.275   1.298   1.400
347   R         1.180   1.198   1.264   1.316   1.336   1.432   1.275   1.298   1.400
348   L         0.542   0.408   0.288   0.497   0.316   0.117   0.538   0.320   0.070
349   Y         0.542   0.408   0.288   0.859   0.695   0.506   0.538   0.320   0.070
350   A         0.021  -0.182  -0.348   0.045  -0.231  -0.483   0.028  -0.255  -0.510
351   A         0.021  -0.182  -0.348   0.063  -0.207  -0.437   0.028  -0.255  -0.510
352   M        -0.519  -0.715  -0.850  -0.206  -0.504  -0.793  -0.470  -0.711  -0.864
353   S         0.021  -0.019  -0.321   0.041  -0.020  -0.446   0.028  -0.040  -0.470
354   A        -0.408  -0.438  -0.409  -0.636  -0.655  -0.625  -0.637  -0.639  -0.603
355   I        -0.258  -0.413  -0.419  -0.303  -0.518  -0.546  -0.387  -0.599  -0.616
356   D        -0.408  -0.505  -0.429  -0.532  -0.674  -0.569  -0.637  -0.748  -0.634
357   I        -1.238  -1.056  -1.215  -1.287  -1.017  -1.239  -1.135  -0.928  -1.050
358   F         0.589   0.505   0.326   0.711   0.611   0.309   0.610   0.478   0.139
359   V         0.589   0.505   0.326   0.606   0.490   0.217   0.610   0.478   0.139
360   N        -0.258  -0.093  -0.350  -0.279  -0.049  -0.422  -0.387  -0.151  -0.515
361   N        -0.408  -0.342  -0.400  -0.369  -0.263  -0.334  -0.637  -0.539  -0.594
362   K        -0.258  -0.385  -0.411  -0.250  -0.424  -0.460  -0.387  -0.565  -0.607
363   G         0.589   0.627   0.340   0.727   0.770   0.361   0.610   0.664   0.166
364   N        -1.499  -1.571  -1.542  -1.237  -1.346  -1.328  -1.218  -1.282  -1.195
365   F        -1.041  -0.956  -0.911  -1.210  -1.067  -1.018  -1.135  -1.029  -0.935
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   L        -0.984  -0.927  -0.906  -1.079  -1.035  -0.912  -1.061  -1.005  -0.930
371   K        -1.028  -1.144  -1.230  -0.875  -1.078  -1.214  -0.886  -1.013  -1.063
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P05150
Output conservation file - output/P05150
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
