1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    M         1.369   1.392   1.462   1.552   1.587   1.689   1.472   1.504   1.609
19    S        -0.450  -0.418  -0.385  -0.857  -0.805  -0.777  -0.664  -0.616  -0.573
20    N        -1.056  -1.034  -0.910  -1.130  -1.096  -0.911  -1.091  -1.056  -0.896
21    K        -1.056  -1.034  -0.910  -1.212  -1.182  -0.990  -1.091  -1.056  -0.896
22    Q         0.385   0.393   0.345   0.197   0.209   0.138   0.191   0.198   0.071
23    A        -0.450  -0.434  -0.397  -0.570  -0.546  -0.484  -0.664  -0.639  -0.589
24    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    K        -0.450  -0.434  -0.397  -0.717  -0.694  -0.633  -0.664  -0.639  -0.589
31    L        -0.450  -0.425  -0.380  -0.698  -0.657  -0.588  -0.664  -0.626  -0.567
32    I        -1.056  -1.034  -0.910  -1.173  -1.140  -0.953  -1.091  -1.056  -0.896
33    S        -1.056  -1.034  -0.910  -1.118  -1.086  -0.899  -1.091  -1.056  -0.896
34    K        -0.450  -0.421  -0.395  -0.725  -0.681  -0.651  -0.664  -0.620  -0.587
35    R         1.369   1.392   1.462   1.465   1.500   1.604   1.472   1.504   1.609
36    W        -0.450  -0.437  -0.388  -0.328  -0.307  -0.242  -0.664  -0.642  -0.578
37    I        -1.362  -1.237  -1.252  -1.290  -1.050  -1.165  -1.186  -1.051  -1.029
38    S        -0.805  -0.821  -0.848  -0.898  -0.941  -0.944  -0.806  -0.826  -0.831
39    T        -0.401  -0.446  -0.362  -0.633  -0.692  -0.592  -0.616  -0.658  -0.546
40    V        -0.805  -0.821  -0.848  -0.744  -0.809  -0.852  -0.806  -0.826  -0.831
41    Q        -1.766  -1.719  -1.603  -1.738  -1.646  -1.500  -1.375  -1.324  -1.174
42    R        -1.766  -1.719  -1.603  -1.501  -1.455  -1.271  -1.375  -1.324  -1.174
43    A        -0.957  -0.959  -0.881  -1.190  -1.207  -1.056  -0.996  -0.987  -0.868
44    D        -1.362  -1.351  -1.275  -1.430  -1.421  -1.273  -1.186  -1.166  -1.050
45    F        -0.957  -0.916  -0.874  -1.071  -1.039  -0.949  -0.996  -0.940  -0.860
46    K        -1.362  -1.363  -1.274  -1.515  -1.547  -1.394  -1.186  -1.177  -1.049
47    L         0.255   0.317   0.328  -0.031   0.070   0.080  -0.047   0.060   0.040
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    N        -0.450  -0.418  -0.385  -0.529  -0.478  -0.459  -0.664  -0.616  -0.573
54    S        -0.962  -0.911  -0.881  -1.168  -1.091  -1.038  -0.988  -0.922  -0.866
55    E        -0.962  -0.943  -0.891  -1.053  -1.036  -0.991  -0.988  -0.959  -0.877
56    A        -0.962  -0.911  -0.881  -1.060  -0.991  -0.953  -0.988  -0.922  -0.866
57    L        -0.294  -0.258  -0.350  -0.437  -0.377  -0.524  -0.441  -0.389  -0.525
58    H         0.493   0.533   0.390   0.606   0.657   0.448   0.379   0.440   0.156
59    S        -0.553  -0.522  -0.416  -0.891  -0.815  -0.668  -0.806  -0.761  -0.615
60    N        -0.149  -0.271  -0.309   0.026  -0.154  -0.229  -0.236  -0.410  -0.467
61    A         0.255   0.333   0.330  -0.089   0.034   0.022  -0.047   0.089   0.044
62    T         0.580   0.453   0.418   0.663   0.490   0.427   0.523   0.304   0.209
63    V         0.156   0.182   0.277  -0.102  -0.057   0.090  -0.236  -0.197  -0.058
64    F         0.580   0.453   0.418   0.734   0.551   0.476   0.523   0.304   0.209
65    S         1.369   1.392   1.462   1.164   1.199   1.313   1.472   1.504   1.609
66    M        -0.303  -0.365  -0.337  -0.234  -0.299  -0.314  -0.481  -0.543  -0.513
67    I         0.651   0.702   0.474   0.666   0.731   0.419   0.635   0.712   0.310
68    Q         1.369   1.392   1.462   1.441   1.460   1.581   1.472   1.504   1.609
69    P         1.369   1.392   1.462   1.421   1.457   1.561   1.472   1.504   1.609
70    T         1.369   1.392   1.462   1.370   1.410   1.512   1.472   1.504   1.609
71    G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
72    C        -1.212  -1.242  -1.234  -1.074  -1.140  -1.074  -1.038  -1.065  -1.013
73    F        -0.303  -0.380  -0.347  -0.262  -0.359  -0.342  -0.481  -0.565  -0.525
74    H         1.369   1.392   1.462   1.523   1.555   1.661   1.472   1.504   1.609
75    L         0.651   0.505   0.440   0.537   0.327   0.226   0.635   0.393   0.249
76    G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
77    N         1.369   1.392   1.462   1.445   1.483   1.585   1.472   1.504   1.609
78    Y         1.369   1.392   1.462   1.512   1.542   1.650   1.472   1.504   1.609
79    L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
80    G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
81    A         0.651   0.505   0.440   0.647   0.430   0.308   0.635   0.393   0.249
82    T        -0.865  -0.894  -0.845  -0.906  -0.958  -0.897  -0.899  -0.916  -0.829
83    R         0.322   0.274   0.306   0.285   0.189   0.187   0.077  -0.021  -0.003
84    V        -1.212  -1.262  -1.249  -1.018  -1.083  -1.089  -1.038  -1.083  -1.026
85    W         1.369   1.392   1.462   1.603   1.635   1.738   1.472   1.504   1.609
86    T        -1.212  -1.242  -1.234  -1.146  -1.190  -1.170  -1.038  -1.065  -1.013
87    D        -0.024  -0.121  -0.268   0.126  -0.026  -0.231  -0.062  -0.205  -0.409
88    L        -0.024   0.029  -0.241  -0.085  -0.013  -0.401  -0.062   0.011  -0.371
89    C        -1.343  -1.355  -1.270  -1.214  -1.228  -1.109  -1.178  -1.174  -1.046
90    E        -0.303  -0.270  -0.320  -0.302  -0.252  -0.349  -0.481  -0.419  -0.488
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    L        -0.996  -0.939  -0.885  -1.334  -1.216  -1.142  -1.038  -0.968  -0.872
94    K        -0.865  -0.915  -0.862  -0.861  -0.910  -0.807  -0.899  -0.943  -0.850
95    Q        -1.343  -1.280  -1.256  -1.259  -1.168  -1.144  -1.178  -1.109  -1.034
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    P         0.651   0.748   0.476   0.784   0.910   0.531   0.635   0.781   0.314
98    G        -0.650  -0.754  -0.817  -0.433  -0.586  -0.726  -0.620  -0.745  -0.795
99    Q        -0.865  -0.894  -0.850  -0.833  -0.890  -0.814  -0.899  -0.916  -0.835
100   E        -0.996  -0.935  -0.883  -1.030  -0.961  -0.861  -1.038  -0.970  -0.872
101   L        -1.212  -1.262  -1.249  -1.087  -1.139  -1.075  -1.038  -1.083  -1.026
102   I        -0.303  -0.294  -0.352  -0.389  -0.394  -0.473  -0.481  -0.497  -0.536
103   F         0.651   0.709   0.471   0.850   0.931   0.610   0.635   0.722   0.306
104   G         0.651   0.505   0.440   0.825   0.626   0.528   0.635   0.393   0.249
105   V        -0.865  -0.802  -0.842  -0.891  -0.784  -0.854  -0.899  -0.818  -0.827
106   A         1.369   1.392   1.462   1.312   1.336   1.456   1.472   1.504   1.609
107   D         1.369   1.392   1.462   1.371   1.395   1.514   1.472   1.504   1.609
108   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
109   H         1.369   1.392   1.462   1.523   1.555   1.661   1.472   1.504   1.609
110   A         1.369   1.392   1.462   1.312   1.336   1.456   1.472   1.504   1.609
111   I         0.651   0.505   0.440   0.633   0.410   0.292   0.635   0.393   0.249
112   T         1.369   1.392   1.462   1.370   1.410   1.512   1.472   1.504   1.609
113   V        -0.303  -0.286  -0.325  -0.307  -0.255  -0.328  -0.481  -0.444  -0.497
114   P         1.369   1.392   1.462   1.421   1.457   1.561   1.472   1.504   1.609
115   K         0.322   0.274   0.304   0.154   0.071   0.116   0.077  -0.020  -0.007
116   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   D         0.322   0.403   0.344   0.274   0.392   0.291   0.077   0.216   0.071
118   G        -0.303  -0.180  -0.316  -0.290  -0.105  -0.307  -0.481  -0.307  -0.482
119   E        -1.343  -1.330  -1.258  -1.465  -1.492  -1.336  -1.178  -1.155  -1.036
120   M        -0.996  -0.933  -0.882  -0.989  -0.939  -0.806  -1.038  -0.968  -0.871
121   F         0.322   0.342   0.324   0.265   0.297   0.200   0.077   0.105   0.032
122   R        -0.388  -0.387  -0.356  -0.494  -0.468  -0.407  -0.620  -0.606  -0.543
123   K        -0.865  -0.781  -0.846  -0.772  -0.685  -0.750  -0.899  -0.817  -0.834
124   F        -1.689  -1.678  -1.578  -1.349  -1.364  -1.206  -1.317  -1.295  -1.156
125   R         1.369   1.392   1.462   1.462   1.504   1.601   1.472   1.504   1.609
126   H        -1.343  -1.332  -1.263  -1.124  -1.152  -1.036  -1.178  -1.156  -1.040
127   E        -0.303  -0.322  -0.353  -0.287  -0.369  -0.391  -0.481  -0.527  -0.538
128   A         0.651   0.505   0.440   0.705   0.512   0.435   0.635   0.393   0.249
129   V        -0.303  -0.295  -0.351  -0.474  -0.526  -0.571  -0.481  -0.498  -0.535
130   A         1.369   1.392   1.462   1.312   1.336   1.456   1.472   1.504   1.609
131   S         0.651   0.505   0.440   0.552   0.377   0.244   0.635   0.393   0.249
132   I         0.174   0.182   0.277  -0.203  -0.215  -0.057  -0.202  -0.196  -0.059
133   L         0.651   0.709   0.471   0.537   0.611   0.279   0.635   0.722   0.306
134   A         0.322   0.403   0.344   0.124   0.263   0.119   0.077   0.216   0.071
135   V        -0.996  -0.953  -0.883  -1.171  -1.106  -1.009  -1.038  -0.984  -0.871
136   G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
137   V        -0.303  -0.211  -0.308  -0.428  -0.283  -0.450  -0.481  -0.346  -0.471
138   D         0.651   0.505   0.440   0.747   0.544   0.453   0.635   0.393   0.249
139   P         0.651   0.709   0.471   0.784   0.865   0.523   0.635   0.722   0.306
140   E        -1.343  -1.344  -1.259  -1.280  -1.290  -1.169  -1.178  -1.164  -1.037
141   K        -0.303  -0.258  -0.325  -0.411  -0.341  -0.434  -0.481  -0.422  -0.497
142   A        -0.388  -0.458  -0.365  -0.398  -0.496  -0.364  -0.620  -0.684  -0.553
143   S        -0.388  -0.459  -0.363  -0.667  -0.734  -0.597  -0.620  -0.686  -0.551
144   V        -0.388  -0.343  -0.357  -0.632  -0.573  -0.571  -0.620  -0.560  -0.544
145   I        -0.650  -0.519  -0.760  -0.342  -0.157  -0.504  -0.620  -0.455  -0.731
146   Y        -0.519  -0.437  -0.388  -0.444  -0.319  -0.251  -0.759  -0.642  -0.577
147   Q         1.369   1.392   1.462   1.441   1.460   1.581   1.472   1.504   1.609
148   S         1.369   1.392   1.462   1.199   1.264   1.347   1.472   1.504   1.609
149   A        -0.865  -0.878  -0.856  -0.964  -0.979  -0.925  -0.899  -0.903  -0.842
150   I         0.174   0.207   0.286  -0.061   0.002   0.108  -0.202  -0.148  -0.041
151   P        -0.024  -0.087  -0.262   0.116   0.017  -0.288  -0.062  -0.163  -0.401
152   Q        -0.388  -0.348  -0.353  -0.410  -0.375  -0.350  -0.620  -0.567  -0.540
153   H         1.369   1.392   1.462   1.523   1.555   1.661   1.472   1.504   1.609
154   S         0.174   0.208   0.284  -0.171  -0.089   0.005  -0.202  -0.145  -0.044
155   E         0.322   0.338   0.327   0.326   0.332   0.307   0.077   0.099   0.038
156   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
157   H        -0.996  -1.021  -0.891  -0.846  -0.898  -0.697  -1.038  -1.043  -0.878
158   W         1.369   1.392   1.462   1.603   1.635   1.738   1.472   1.504   1.609
159   L        -0.650  -0.603  -0.788  -0.648  -0.586  -0.831  -0.620  -0.558  -0.763
160   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
161   S        -0.303  -0.380  -0.347  -0.499  -0.580  -0.557  -0.481  -0.565  -0.525
162   T        -0.865  -0.793  -0.845  -0.676  -0.537  -0.669  -0.899  -0.805  -0.829
163   L        -1.343  -1.259  -1.252  -1.475  -1.326  -1.301  -1.178  -1.087  -1.031
164   A        -0.388  -0.381  -0.360  -0.549  -0.529  -0.489  -0.620  -0.596  -0.547
165   S        -0.024  -0.012  -0.243  -0.033   0.015  -0.322  -0.062  -0.044  -0.374
166   M         1.369   1.392   1.462   1.543   1.582   1.680   1.472   1.504   1.609
167   G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
168   L        -1.343  -1.328  -1.258  -1.342  -1.287  -1.220  -1.178  -1.153  -1.036
169   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
170   N         1.369   1.392   1.462   1.445   1.483   1.585   1.472   1.504   1.609
171   R         1.369   1.392   1.462   1.462   1.504   1.601   1.472   1.504   1.609
172   M         1.369   1.392   1.462   1.543   1.582   1.680   1.472   1.504   1.609
173   T         0.651   0.635   0.460   0.735   0.726   0.461   0.635   0.606   0.285
174   Q         1.369   1.392   1.462   1.441   1.460   1.581   1.472   1.504   1.609
175   W         1.369   1.392   1.462   1.603   1.635   1.738   1.472   1.504   1.609
176   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
177   S         0.651   0.710   0.473   0.531   0.643   0.255   0.635   0.723   0.309
178   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
179   S        -0.303  -0.406  -0.353  -0.557  -0.706  -0.653  -0.481  -0.605  -0.536
180   N        -0.865  -0.942  -0.868  -0.684  -0.783  -0.665  -0.899  -0.964  -0.855
181   I        -0.996  -0.973  -0.886  -1.154  -1.141  -0.985  -1.038  -0.998  -0.874
182   K        -2.035  -1.984  -1.867  -1.858  -1.737  -1.617  -1.457  -1.404  -1.254
183   Q        -0.388  -0.319  -0.345  -0.430  -0.364  -0.341  -0.620  -0.539  -0.531
184   S        -1.689  -1.652  -1.581  -1.531  -1.448  -1.345  -1.317  -1.275  -1.158
185   T        -1.212  -1.245  -1.235  -1.265  -1.303  -1.308  -1.038  -1.068  -1.014
186   N        -0.957  -0.885  -0.866  -1.070  -0.951  -0.914  -0.996  -0.913  -0.854
187   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   Y        -0.477  -0.430  -0.384  -0.533  -0.449  -0.370  -0.715  -0.648  -0.576
190   L         0.191   0.223   0.291  -0.095  -0.049   0.066  -0.168  -0.116  -0.032
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   V        -0.450  -0.389  -0.371  -0.620  -0.515  -0.500  -0.664  -0.575  -0.554
193   N        -1.212  -1.203  -1.226  -1.056  -1.085  -1.099  -1.038  -1.027  -1.005
194   D        -0.865  -0.868  -0.849  -0.908  -0.947  -0.895  -0.899  -0.899  -0.836
195   S        -2.035  -1.984  -1.867  -1.918  -1.817  -1.675  -1.457  -1.404  -1.254
196   D        -1.689  -1.664  -1.589  -1.649  -1.644  -1.532  -1.317  -1.285  -1.164
197   V        -0.024  -0.089  -0.262  -0.106  -0.215  -0.475  -0.062  -0.165  -0.401
198   G        -0.650  -0.754  -0.817  -0.442  -0.617  -0.740  -0.620  -0.745  -0.795
199   K        -1.212  -1.244  -1.232  -1.109  -1.151  -1.118  -1.038  -1.067  -1.011
200   V        -1.343  -1.355  -1.270  -1.313  -1.312  -1.217  -1.178  -1.174  -1.046
201   R        -0.024  -0.089  -0.262   0.022  -0.065  -0.295  -0.062  -0.165  -0.401
202   L        -0.303  -0.283  -0.328  -0.488  -0.452  -0.487  -0.481  -0.439  -0.498
203   G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
204   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
205   F         0.651   0.710   0.473   0.797   0.884   0.506   0.635   0.723   0.309
206   S        -0.303  -0.230  -0.318  -0.353  -0.230  -0.338  -0.481  -0.373  -0.485
207   Y         1.369   1.392   1.462   1.512   1.542   1.650   1.472   1.504   1.609
208   P         1.369   1.392   1.462   1.421   1.457   1.561   1.472   1.504   1.609
209   V         0.322   0.341   0.322   0.234   0.271   0.191   0.077   0.105   0.028
210   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
211   Q         1.369   1.392   1.462   1.441   1.460   1.581   1.472   1.504   1.609
212   A         1.369   1.392   1.462   1.312   1.336   1.456   1.472   1.504   1.609
213   A         1.369   1.392   1.462   1.312   1.336   1.456   1.472   1.504   1.609
214   D         1.369   1.392   1.462   1.371   1.395   1.514   1.472   1.504   1.609
215   I         1.369   1.392   1.462   1.301   1.328   1.445   1.472   1.504   1.609
216   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
217   L        -0.024  -0.005  -0.241  -0.051  -0.023  -0.340  -0.062  -0.035  -0.371
218   Y         0.651   0.710   0.473   0.889   0.964   0.641   0.635   0.723   0.309
219   K         0.651   0.505   0.440   0.623   0.436   0.339   0.635   0.393   0.249
220   S         0.322   0.271   0.306   0.058  -0.015   0.004   0.077  -0.025  -0.003
221   T         1.369   1.392   1.462   1.370   1.410   1.512   1.472   1.504   1.609
222   H         1.369   1.392   1.462   1.523   1.555   1.661   1.472   1.504   1.609
223   V         0.651   0.505   0.440   0.735   0.540   0.410   0.635   0.393   0.249
224   P         1.369   1.392   1.462   1.421   1.457   1.561   1.472   1.504   1.609
225   V         1.369   1.392   1.462   1.383   1.431   1.525   1.472   1.504   1.609
226   G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
227   D        -0.024  -0.184  -0.285   0.099  -0.155  -0.310  -0.062  -0.288  -0.433
228   D         1.369   1.392   1.462   1.371   1.395   1.514   1.472   1.504   1.609
229   Q         1.369   1.392   1.462   1.441   1.460   1.581   1.472   1.504   1.609
230   S         0.651   0.702   0.474   0.565   0.667   0.324   0.635   0.712   0.310
231   Q         1.369   1.392   1.462   1.441   1.460   1.581   1.472   1.504   1.609
232   H         1.369   1.392   1.462   1.523   1.555   1.661   1.472   1.504   1.609
233   L         0.651   0.505   0.440   0.551   0.355   0.258   0.635   0.393   0.249
234   E         1.369   1.392   1.462   1.428   1.452   1.569   1.472   1.504   1.609
235   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
236   T         0.322   0.382   0.349   0.334   0.426   0.376   0.077   0.178   0.079
237   R         1.369   1.392   1.462   1.462   1.504   1.601   1.472   1.504   1.609
238   H        -1.689  -1.589  -1.572  -1.554  -1.423  -1.364  -1.317  -1.219  -1.152
239   L        -0.388  -0.381  -0.360  -0.692  -0.672  -0.618  -0.620  -0.596  -0.547
240   A         0.651   0.748   0.476   0.647   0.771   0.372   0.635   0.781   0.314
241   E        -1.689  -1.675  -1.590  -1.493  -1.460  -1.369  -1.317  -1.293  -1.165
242   K        -0.865  -0.814  -0.850  -0.956  -0.895  -0.945  -0.899  -0.850  -0.838
243   F         1.369   1.392   1.462   1.464   1.504   1.603   1.472   1.504   1.609
244   N         1.369   1.392   1.462   1.445   1.483   1.585   1.472   1.504   1.609
245   K        -0.865  -0.868  -0.860  -1.021  -1.027  -0.987  -0.899  -0.899  -0.848
246   M        -1.689  -1.664  -1.589  -1.521  -1.517  -1.383  -1.317  -1.285  -1.164
247   Y         0.651   0.710   0.473   0.889   0.964   0.641   0.635   0.723   0.309
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
252   K        -0.388  -0.459  -0.363  -0.565  -0.643  -0.493  -0.620  -0.686  -0.551
253   N        -0.865  -0.869  -0.848  -0.817  -0.845  -0.794  -0.899  -0.899  -0.836
254   F        -0.996  -1.023  -0.888  -0.919  -0.963  -0.764  -1.038  -1.046  -0.876
255   F         0.651   0.505   0.440   0.797   0.585   0.445   0.635   0.393   0.249
256   P         0.651   0.505   0.440   0.784   0.586   0.470   0.635   0.393   0.249
257   K        -1.212  -1.219  -1.237  -1.220  -1.239  -1.241  -1.038  -1.044  -1.015
258   P         1.369   1.392   1.462   1.421   1.457   1.561   1.472   1.504   1.609
259   V        -1.689  -1.653  -1.582  -1.592  -1.522  -1.451  -1.317  -1.276  -1.159
260   T         0.651   0.505   0.440   0.721   0.519   0.398   0.635   0.393   0.249
261   M        -0.303  -0.268  -0.340  -0.488  -0.473  -0.510  -0.481  -0.452  -0.519
262   L         0.651   0.635   0.460   0.565   0.548   0.319   0.635   0.606   0.285
263   A        -0.303  -0.380  -0.347  -0.363  -0.463  -0.414  -0.481  -0.565  -0.525
264   Q        -0.024  -0.089  -0.262   0.141   0.028  -0.241  -0.062  -0.165  -0.401
265   T        -0.303  -0.380  -0.347  -0.393  -0.506  -0.496  -0.481  -0.565  -0.525
266   K         0.651   0.505   0.440   0.581   0.381   0.245   0.635   0.393   0.249
267   K         0.651   0.505   0.440   0.581   0.381   0.245   0.635   0.393   0.249
268   V        -0.024   0.096  -0.222   0.079   0.233  -0.181  -0.062   0.106  -0.344
269   L        -0.024  -0.184  -0.285  -0.049  -0.261  -0.399  -0.062  -0.288  -0.433
270   S         0.651   0.505   0.440   0.552   0.377   0.244   0.635   0.393   0.249
271   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
272   S        -1.689  -1.637  -1.577  -1.536  -1.388  -1.398  -1.317  -1.264  -1.155
273   T        -1.212  -1.245  -1.235  -0.913  -0.981  -0.958  -1.038  -1.068  -1.014
274   P         0.651   0.702   0.474   0.784   0.854   0.527   0.635   0.712   0.310
275   E        -0.865  -0.830  -0.841  -0.825  -0.773  -0.799  -0.899  -0.846  -0.827
276   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
277   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
278   M         1.369   1.392   1.462   1.543   1.582   1.680   1.472   1.504   1.609
279   S         1.369   1.392   1.462   1.199   1.264   1.347   1.472   1.504   1.609
280   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
281   S         1.369   1.392   1.462   1.199   1.264   1.347   1.472   1.504   1.609
282   D         1.369   1.392   1.462   1.371   1.395   1.514   1.472   1.504   1.609
283   P        -0.650  -0.670  -0.796  -0.471  -0.528  -0.731  -0.620  -0.651  -0.771
284   N        -0.024   0.062  -0.239   0.187   0.309  -0.141  -0.062   0.059  -0.368
285   H        -1.212  -1.242  -1.234  -1.040  -1.143  -1.125  -1.038  -1.065  -1.013
286   D        -1.343  -1.369  -1.266  -1.199  -1.253  -1.082  -1.178  -1.185  -1.042
287   S        -0.650  -0.759  -0.809  -0.632  -0.764  -0.846  -0.620  -0.750  -0.787
288   V        -0.865  -0.942  -0.868  -0.711  -0.796  -0.713  -0.899  -0.964  -0.855
289   I         0.651   0.709   0.471   0.666   0.739   0.416   0.635   0.722   0.306
290   F        -0.303  -0.395  -0.350  -0.198  -0.355  -0.312  -0.481  -0.587  -0.531
291   L        -0.519  -0.511  -0.413  -0.784  -0.788  -0.647  -0.759  -0.746  -0.611
292   N        -0.303  -0.369  -0.335  -0.332  -0.421  -0.402  -0.481  -0.548  -0.508
293   D         0.322   0.342   0.324   0.267   0.281   0.246   0.077   0.105   0.032
294   E        -0.303  -0.195  -0.313  -0.445  -0.258  -0.435  -0.481  -0.318  -0.479
295   P         0.651   0.505   0.440   0.784   0.586   0.470   0.635   0.393   0.249
296   K        -0.650  -0.672  -0.792  -0.444  -0.495  -0.686  -0.620  -0.653  -0.767
297   A        -1.689  -1.678  -1.577  -1.539  -1.536  -1.374  -1.317  -1.295  -1.156
298   I         1.369   1.392   1.462   1.301   1.328   1.445   1.472   1.504   1.609
299   Q        -1.343  -1.372  -1.259  -1.203  -1.240  -1.065  -1.178  -1.186  -1.037
300   K        -0.024   0.055  -0.228   0.026   0.140  -0.238  -0.062   0.050  -0.352
301   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
302   I         0.651   0.635   0.460   0.680   0.658   0.426   0.635   0.606   0.285
303   R        -0.303  -0.366  -0.338  -0.437  -0.519  -0.495  -0.481  -0.544  -0.515
304   K        -0.303  -0.350  -0.352  -0.437  -0.492  -0.512  -0.481  -0.546  -0.535
305   A         1.369   1.392   1.462   1.312   1.336   1.456   1.472   1.504   1.609
306   L        -1.343  -1.332  -1.264  -1.266  -1.232  -1.147  -1.178  -1.157  -1.041
307   T         0.651   0.635   0.460   0.705   0.696   0.397   0.635   0.606   0.285
308   D         1.369   1.392   1.462   1.371   1.395   1.514   1.472   1.504   1.609
309   S         0.651   0.505   0.440   0.576   0.415   0.295   0.635   0.393   0.249
310   I         0.651   0.635   0.460   0.664   0.638   0.393   0.635   0.606   0.285
311   S        -1.343  -1.371  -1.269  -1.360  -1.393  -1.244  -1.178  -1.186  -1.045
312   D        -0.388  -0.381  -0.360  -0.447  -0.437  -0.391  -0.620  -0.596  -0.547
313   R        -1.343  -1.355  -1.255  -1.448  -1.445  -1.288  -1.178  -1.175  -1.034
314   F        -0.303  -0.380  -0.347  -0.274  -0.375  -0.361  -0.481  -0.565  -0.525
315   Y         0.651   0.635   0.460   0.845   0.819   0.527   0.635   0.606   0.285
316   Y        -0.024  -0.087  -0.262   0.282   0.179  -0.066  -0.062  -0.163  -0.401
317   D         1.369   1.392   1.462   1.371   1.395   1.514   1.472   1.504   1.609
318   P         0.651   0.505   0.440   0.756   0.550   0.409   0.635   0.393   0.249
319   V        -0.401  -0.396  -0.379  -0.479  -0.488  -0.452  -0.616  -0.610  -0.570
320   E        -0.865  -0.745  -0.825  -0.744  -0.561  -0.682  -0.899  -0.753  -0.810
321   R         1.369   1.392   1.462   1.462   1.504   1.601   1.472   1.504   1.609
322   P         1.369   1.392   1.462   1.421   1.457   1.561   1.472   1.504   1.609
323   G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
324   V        -0.519  -0.471  -0.402  -0.806  -0.734  -0.632  -0.759  -0.691  -0.597
325   S         0.651   0.505   0.440   0.576   0.415   0.295   0.635   0.393   0.249
326   N         1.369   1.392   1.462   1.445   1.483   1.585   1.472   1.504   1.609
327   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
328   I         0.651   0.635   0.460   0.694   0.673   0.454   0.635   0.606   0.285
329   N         0.651   0.635   0.460   0.808   0.795   0.526   0.635   0.606   0.285
330   I         0.651   0.748   0.476   0.664   0.783   0.418   0.635   0.781   0.314
331   V        -1.212  -1.240  -1.237  -1.029  -1.047  -1.085  -1.038  -1.063  -1.015
332   S         0.322   0.248   0.296   0.058  -0.059  -0.014   0.077  -0.070  -0.023
333   G         0.651   0.505   0.440   0.800   0.584   0.474   0.635   0.393   0.249
334   I        -0.303  -0.241  -0.324  -0.428  -0.334  -0.477  -0.481  -0.394  -0.495
335   Q        -0.388  -0.343  -0.357  -0.560  -0.496  -0.495  -0.620  -0.560  -0.544
336   R        -0.650  -0.705  -0.800  -0.412  -0.504  -0.674  -0.620  -0.690  -0.776
337   K        -0.865  -0.913  -0.853  -0.971  -1.040  -0.942  -0.899  -0.939  -0.839
338   S        -0.303  -0.383  -0.341  -0.461  -0.536  -0.496  -0.481  -0.569  -0.519
339   I        -0.388  -0.460  -0.365  -0.518  -0.596  -0.452  -0.620  -0.687  -0.553
340   E        -1.212  -1.225  -1.237  -0.994  -1.053  -1.060  -1.038  -1.047  -1.015
341   D        -0.024   0.055  -0.228   0.112   0.206  -0.191  -0.062   0.050  -0.352
342   V        -0.024  -0.120  -0.265   0.109  -0.029  -0.269  -0.062  -0.204  -0.405
343   V        -0.388  -0.459  -0.360  -0.452  -0.552  -0.400  -0.620  -0.686  -0.548
344   E        -0.519  -0.498  -0.410  -0.689  -0.665  -0.512  -0.759  -0.730  -0.607
345   D        -0.650  -0.759  -0.809  -0.470  -0.662  -0.715  -0.620  -0.750  -0.787
346   V        -1.343  -1.330  -1.258  -1.350  -1.322  -1.184  -1.178  -1.155  -1.036
347   S        -0.865  -0.772  -0.833  -1.025  -0.863  -0.974  -0.899  -0.780  -0.818
348   R        -1.689  -1.589  -1.572  -1.507  -1.374  -1.314  -1.317  -1.219  -1.152
349   F        -0.865  -0.909  -0.857  -0.737  -0.775  -0.706  -0.899  -0.935  -0.844
350   N        -1.212  -1.203  -1.226  -1.187  -1.193  -1.213  -1.038  -1.027  -1.005
351   N        -0.303  -0.266  -0.324  -0.259  -0.188  -0.300  -0.481  -0.413  -0.494
352   Y        -0.401  -0.422  -0.371  -0.262  -0.292  -0.217  -0.616  -0.631  -0.558
353   R        -0.865  -0.937  -0.858  -0.892  -0.991  -0.857  -0.899  -0.957  -0.843
354   D        -0.519  -0.511  -0.412  -0.594  -0.606  -0.432  -0.759  -0.747  -0.610
355   F         0.174   0.189   0.279  -0.121  -0.095   0.054  -0.202  -0.183  -0.056
356   K         1.369   1.392   1.462   1.246   1.287   1.392   1.472   1.504   1.609
357   D        -1.212  -1.244  -1.232  -1.061  -1.145  -1.114  -1.038  -1.067  -1.011
358   Y        -0.865  -0.935  -0.854  -0.677  -0.801  -0.686  -0.899  -0.955  -0.841
359   V         1.369   1.392   1.462   1.383   1.431   1.525   1.472   1.504   1.609
360   S         0.174   0.226   0.290  -0.171  -0.059   0.013  -0.202  -0.111  -0.034
361   E        -0.303  -0.394  -0.350  -0.312  -0.469  -0.424  -0.481  -0.587  -0.531
362   V        -0.650  -0.753  -0.815  -0.552  -0.721  -0.869  -0.620  -0.745  -0.793
363   I        -0.024   0.029  -0.241   0.007   0.081  -0.338  -0.062   0.011  -0.371
364   I         0.174   0.208   0.284  -0.078  -0.022   0.093  -0.202  -0.145  -0.044
365   E        -0.024  -0.121  -0.268   0.153   0.014  -0.236  -0.062  -0.205  -0.409
366   E        -0.024  -0.184  -0.285   0.215  -0.006  -0.146  -0.062  -0.288  -0.433
367   L         0.322   0.382   0.349   0.105   0.195   0.147   0.077   0.178   0.079
368   K        -1.689  -1.653  -1.582  -1.547  -1.497  -1.388  -1.317  -1.276  -1.159
369   G        -0.865  -0.758  -0.833  -0.779  -0.624  -0.718  -0.899  -0.771  -0.817
370   P        -1.343  -1.355  -1.270  -1.397  -1.403  -1.300  -1.178  -1.174  -1.046
371   R         0.651   0.505   0.440   0.797   0.597   0.448   0.635   0.393   0.249
372   T        -1.343  -1.299  -1.253  -1.210  -1.160  -1.076  -1.178  -1.124  -1.032
373   E        -1.343  -1.332  -1.263  -1.432  -1.442  -1.312  -1.178  -1.156  -1.040
374   F         0.651   0.709   0.471   0.850   0.931   0.610   0.635   0.722   0.306
375   E        -0.996  -0.975  -0.884  -0.877  -0.854  -0.714  -1.038  -1.000  -0.872
376   K        -0.865  -0.771  -0.844  -0.762  -0.631  -0.735  -0.899  -0.788  -0.830
377   Y        -0.388  -0.458  -0.365  -0.459  -0.535  -0.378  -0.620  -0.684  -0.553
378   I        -0.650  -0.727  -0.813  -0.347  -0.466  -0.651  -0.620  -0.716  -0.791
379   N        -1.343  -1.346  -1.255  -1.256  -1.249  -1.113  -1.178  -1.167  -1.034
380   E        -0.303  -0.268  -0.340  -0.279  -0.259  -0.327  -0.481  -0.452  -0.519
381   P        -0.865  -0.831  -0.858  -0.762  -0.712  -0.753  -0.899  -0.865  -0.846
382   T        -2.035  -1.984  -1.867  -1.853  -1.770  -1.612  -1.457  -1.404  -1.254
383   Y        -0.024  -0.127  -0.265   0.233   0.056  -0.162  -0.062  -0.213  -0.405
384   L         1.369   1.392   1.462   1.185   1.217   1.333   1.472   1.504   1.609
385   H        -0.865  -0.926  -0.858  -0.720  -0.805  -0.687  -0.899  -0.944  -0.845
386   S        -0.865  -0.804  -0.841  -1.082  -0.974  -1.050  -0.899  -0.838  -0.829
387   V        -0.303  -0.195  -0.313  -0.385  -0.215  -0.393  -0.481  -0.318  -0.479
388   V        -0.865  -0.878  -0.856  -0.765  -0.783  -0.774  -0.899  -0.903  -0.842
389   E        -1.343  -1.297  -1.253  -1.319  -1.259  -1.187  -1.178  -1.120  -1.032
390   S        -1.343  -1.229  -1.248  -1.356  -1.203  -1.224  -1.178  -1.065  -1.028
391   G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
392   M        -1.343  -1.286  -1.250  -1.192  -1.129  -1.031  -1.178  -1.115  -1.029
393   R        -2.035  -1.984  -1.867  -1.874  -1.796  -1.633  -1.457  -1.404  -1.254
394   K        -0.024  -0.127  -0.265   0.018  -0.121  -0.305  -0.062  -0.213  -0.405
395   A         1.369   1.392   1.462   1.312   1.336   1.456   1.472   1.504   1.609
396   R        -0.024  -0.127  -0.265   0.171   0.035  -0.231  -0.062  -0.213  -0.405
397   E         0.651   0.505   0.440   0.782   0.562   0.456   0.635   0.393   0.249
398   K        -0.865  -0.910  -0.854  -1.012  -1.075  -0.999  -0.899  -0.936  -0.841
399   A         0.651   0.710   0.473   0.675   0.745   0.425   0.635   0.723   0.309
400   A        -0.388  -0.330  -0.348  -0.705  -0.606  -0.643  -0.620  -0.540  -0.531
401   K        -0.519  -0.507  -0.409  -0.842  -0.811  -0.683  -0.759  -0.741  -0.606
402   N        -0.303  -0.408  -0.348  -0.207  -0.333  -0.258  -0.481  -0.608  -0.528
403   L        -0.519  -0.498  -0.407  -0.748  -0.696  -0.556  -0.759  -0.730  -0.604
404   A        -1.343  -1.239  -1.250  -1.241  -1.088  -1.098  -1.178  -1.077  -1.030
405   D        -0.650  -0.673  -0.796  -0.445  -0.525  -0.696  -0.620  -0.653  -0.772
406   I        -0.865  -0.919  -0.852  -0.949  -1.051  -0.935  -0.899  -0.947  -0.839
407   H        -0.650  -0.579  -0.782  -0.493  -0.398  -0.628  -0.620  -0.531  -0.756
408   K        -1.689  -1.678  -1.577  -1.618  -1.592  -1.445  -1.317  -1.295  -1.156
409   I        -0.303  -0.327  -0.349  -0.477  -0.571  -0.572  -0.481  -0.533  -0.532
410   M        -0.865  -0.915  -0.862  -0.737  -0.824  -0.761  -0.899  -0.943  -0.850
411   G         1.369   1.392   1.462   1.447   1.474   1.587   1.472   1.504   1.609
412   F        -0.303  -0.306  -0.351  -0.284  -0.330  -0.384  -0.481  -0.499  -0.535
413   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
414   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
415   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
416   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
417   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
418   -        -1.362  -1.363  -1.275  -1.374  -1.376  -1.270  -1.186  -1.176  -1.050
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P04803
Output conservation file - output/P04803
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
