1     M         1.015   1.069   1.116   1.312   1.371   1.422   1.055   1.125   1.200
2     S        -1.227  -1.241  -1.022  -1.416  -1.362  -1.054  -1.364  -1.320  -1.045
3     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    P        -1.815  -1.682  -1.572  -1.830  -1.640  -1.509  -1.692  -1.489  -1.319
15    K         0.106   0.007  -0.167   0.262   0.158  -0.092   0.086  -0.057  -0.367
16    K        -1.376  -1.281  -1.040  -1.448  -1.292  -0.960  -1.530  -1.366  -1.065
17    I         1.015   1.069   1.116   1.025   1.108   1.181   1.055   1.125   1.200
18    V        -0.311  -0.135  -0.201  -0.473  -0.189  -0.311  -0.561  -0.278  -0.423
19    V         1.015   1.069   1.116   0.939   1.016   1.108   1.055   1.125   1.200
20    L         0.106   0.007  -0.167  -0.068  -0.157  -0.349   0.086  -0.057  -0.367
21    P         0.106   0.007  -0.167   0.236   0.105  -0.227   0.086  -0.057  -0.367
22    G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
23    D         1.015   1.069   1.116   1.071   1.151   1.219   1.055   1.125   1.200
24    H         1.015   1.069   1.116   1.321   1.382   1.430   1.055   1.125   1.200
25    V        -0.750  -1.035  -1.010  -0.606  -0.980  -0.929  -0.722  -1.059  -1.029
26    G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
27    Q        -2.420  -2.033  -2.028  -2.148  -1.601  -1.656  -2.015  -1.592  -1.508
28    E         1.015   1.069   1.116   0.991   1.062   1.152   1.055   1.125   1.200
29    I        -0.499  -0.391  -0.243  -0.821  -0.625  -0.412  -0.884  -0.702  -0.496
30    T        -1.211  -0.964  -0.993  -1.290  -0.930  -0.891  -1.368  -1.017  -1.010
31    A        -2.420  -2.158  -2.023  -2.519  -2.192  -1.976  -2.015  -1.715  -1.505
32    E         0.106  -0.101  -0.176   0.170  -0.122  -0.275   0.086  -0.224  -0.381
33    A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
34    I         0.106  -0.101  -0.176   0.157  -0.160  -0.375   0.086  -0.224  -0.381
35    K         0.106  -0.101  -0.176   0.206  -0.085  -0.248   0.086  -0.224  -0.381
36    V         1.015   1.069   1.116   0.939   1.016   1.108   1.055   1.125   1.200
37    L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
38    K        -1.103  -0.763  -0.970  -1.019  -0.516  -0.792  -1.207  -0.729  -0.981
39    A         0.106  -0.101  -0.176  -0.036  -0.304  -0.448   0.086  -0.224  -0.381
40    I         0.106  -0.101  -0.176   0.195  -0.094  -0.273   0.086  -0.224  -0.381
41    S        -1.542  -1.025  -1.535  -1.390  -0.673  -1.422  -1.368  -0.757  -1.283
42    D        -2.420  -2.337  -2.036  -2.408  -2.231  -1.872  -2.015  -1.843  -1.514
43    V        -2.420  -2.307  -2.039  -2.406  -2.192  -1.765  -2.015  -1.825  -1.516
44    R        -1.103  -1.060  -1.005  -0.963  -0.876  -0.880  -1.207  -1.093  -1.023
45    S         0.106   0.325  -0.145   0.245   0.533  -0.162   0.086   0.390  -0.330
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    N        -1.981  -1.859  -1.591  -2.070  -1.888  -1.523  -1.853  -1.643  -1.337
49    V        -1.815  -1.845  -1.593  -1.983  -2.063  -1.716  -1.692  -1.630  -1.338
50    K        -0.750  -0.438  -0.949  -0.504  -0.099  -0.761  -0.722  -0.313  -0.954
51    F         0.106  -0.101  -0.176   0.410   0.074  -0.180   0.086  -0.224  -0.381
52    D        -1.815  -1.685  -1.574  -1.674  -1.486  -1.367  -1.692  -1.496  -1.321
53    F        -0.311  -0.274  -0.235  -0.294  -0.263  -0.344  -0.561  -0.504  -0.482
54    E        -1.815  -1.571  -1.568  -1.607  -1.283  -1.314  -1.692  -1.406  -1.317
55    N        -1.815  -1.777  -1.585  -1.502  -1.488  -1.267  -1.692  -1.585  -1.332
56    H         1.015   1.069   1.116   1.321   1.382   1.430   1.055   1.125   1.200
57    L         0.106  -0.101  -0.176  -0.113  -0.379  -0.477   0.086  -0.224  -0.381
58    I         0.106   0.007  -0.167   0.157   0.021  -0.356   0.086  -0.057  -0.367
59    G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
60    G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
61    A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
62    A        -0.311  -0.397  -0.244  -0.650  -0.781  -0.529  -0.561  -0.713  -0.498
63    I         1.015   1.069   1.116   1.025   1.108   1.181   1.055   1.125   1.200
64    D         1.015   1.069   1.116   1.071   1.151   1.219   1.055   1.125   1.200
65    A         0.106   0.007  -0.167  -0.021  -0.117  -0.394   0.086  -0.057  -0.367
66    T        -0.750  -1.035  -1.010  -0.403  -0.747  -0.720  -0.722  -1.059  -1.029
67    G         0.106   0.007  -0.167   0.145   0.029  -0.222   0.086  -0.057  -0.367
68    V        -1.211  -1.169  -1.008  -1.360  -1.220  -1.005  -1.368  -1.241  -1.028
69    P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
70    L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
71    P        -0.311  -0.397  -0.244  -0.353  -0.516  -0.297  -0.561  -0.713  -0.498
72    D         1.015   1.069   1.116   1.071   1.151   1.219   1.055   1.125   1.200
73    E         0.106   0.256  -0.149   0.183   0.383  -0.194   0.086   0.298  -0.335
74    A        -0.750  -0.825  -0.982  -0.811  -0.889  -1.117  -0.722  -0.815  -0.994
75    L         0.106  -0.101  -0.176  -0.129  -0.407  -0.518   0.086  -0.224  -0.381
76    E        -0.750  -1.035  -1.010  -0.591  -0.993  -0.975  -0.722  -1.059  -1.029
77    A         0.106   0.256  -0.149  -0.027   0.202  -0.377   0.086   0.298  -0.335
78    S        -1.211  -1.215  -1.014  -1.466  -1.356  -1.047  -1.368  -1.289  -1.034
79    K         0.106  -0.101  -0.176   0.160  -0.165  -0.373   0.086  -0.224  -0.381
80    K        -2.254  -2.242  -2.038  -2.116  -2.158  -1.874  -1.853  -1.772  -1.515
81    A        -0.311  -0.135  -0.201  -0.650  -0.340  -0.465  -0.561  -0.278  -0.423
82    D         1.015   1.069   1.116   1.071   1.151   1.219   1.055   1.125   1.200
83    A         0.106  -0.101  -0.176  -0.037  -0.308  -0.450   0.086  -0.224  -0.381
84    V         1.015   1.069   1.116   0.939   1.016   1.108   1.055   1.125   1.200
85    L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
86    L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
87    G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
88    A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
89    V         0.106   0.007  -0.167   0.124   0.005  -0.285   0.086  -0.057  -0.367
90    G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
91    G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
92    P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
93    K        -0.311  -0.397  -0.244  -0.428  -0.614  -0.382  -0.561  -0.713  -0.498
94    W         1.015   1.069   1.116   1.349   1.406   1.453   1.055   1.125   1.200
95    G         0.106  -0.101  -0.176   0.131  -0.147  -0.273   0.086  -0.224  -0.381
96    T         0.106  -0.101  -0.176   0.302   0.034  -0.119   0.086  -0.224  -0.381
97    G        -0.750  -1.035  -1.010  -0.677  -1.085  -1.077  -0.722  -1.059  -1.029
98    S        -1.815  -1.702  -1.570  -1.910  -1.640  -1.491  -1.692  -1.500  -1.317
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   V         0.106  -0.101  -0.176   0.181  -0.064  -0.153   0.086  -0.224  -0.381
101   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
102   P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
103   E         1.015   1.069   1.116   0.991   1.062   1.152   1.055   1.125   1.200
104   Q         1.015   1.069   1.116   1.286   1.362   1.400   1.055   1.125   1.200
105   G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
106   L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
107   L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
108   K         1.015   1.069   1.116   1.027   1.103   1.183   1.055   1.125   1.200
109   I        -0.311  -0.397  -0.244  -0.538  -0.779  -0.556  -0.561  -0.713  -0.498
110   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
111   K         1.015   1.069   1.116   1.027   1.103   1.183   1.055   1.125   1.200
112   E         0.106  -0.101  -0.176   0.170  -0.122  -0.275   0.086  -0.224  -0.381
113   L         0.106  -0.101  -0.176  -0.061  -0.288  -0.342   0.086  -0.224  -0.381
114   Q        -1.376  -1.103  -1.010  -1.434  -1.040  -0.895  -1.530  -1.144  -1.029
115   L        -0.750  -1.035  -1.010  -0.915  -1.306  -1.240  -0.722  -1.059  -1.029
116   Y         0.106  -0.101  -0.176   0.567   0.287   0.127   0.086  -0.224  -0.381
117   A         0.106   0.007  -0.167  -0.037  -0.142  -0.435   0.086  -0.057  -0.367
118   N         1.015   1.069   1.116   1.178   1.245   1.310   1.055   1.125   1.200
119   L         0.106   0.256  -0.149  -0.113   0.104  -0.435   0.086   0.298  -0.335
120   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
121   P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
122   C         1.015   1.069   1.116   1.353   1.403   1.457   1.055   1.125   1.200
123   N         1.015   1.069   1.116   1.178   1.245   1.310   1.055   1.125   1.200
124   F         1.015   1.069   1.116   1.277   1.345   1.393   1.055   1.125   1.200
125   A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
126   S         1.015   1.069   1.116   0.993   1.073   1.154   1.055   1.125   1.200
127   D        -0.750  -1.035  -1.010  -0.550  -0.970  -1.007  -0.722  -1.059  -1.029
128   S         1.015   1.069   1.116   0.993   1.073   1.154   1.055   1.125   1.200
129   L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
130   L        -0.311  -0.397  -0.244  -0.761  -0.905  -0.623  -0.561  -0.713  -0.498
131   D        -1.103  -1.137  -1.010  -1.124  -1.141  -1.010  -1.207  -1.187  -1.030
132   L        -0.750  -1.035  -1.010  -0.851  -1.185  -1.098  -0.722  -1.059  -1.029
133   S         1.015   1.069   1.116   0.993   1.073   1.154   1.055   1.125   1.200
134   P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
135   I         0.106   0.325  -0.145  -0.113   0.185  -0.430   0.086   0.390  -0.330
136   K         1.015   1.069   1.116   1.027   1.103   1.183   1.055   1.125   1.200
137   P        -1.103  -0.968  -1.007  -1.224  -1.034  -1.134  -1.207  -1.024  -1.029
138   Q         0.106   0.325  -0.145   0.220   0.490  -0.101   0.086   0.390  -0.330
139   F        -1.815  -1.499  -1.562  -1.707  -1.316  -1.291  -1.692  -1.338  -1.311
140   A        -1.211  -1.151  -1.008  -1.506  -1.286  -1.048  -1.368  -1.216  -1.027
141   K        -1.103  -1.202  -1.019  -1.073  -1.207  -0.951  -1.207  -1.271  -1.042
142   G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
143   T         0.106  -0.101  -0.176   0.263  -0.034  -0.222   0.086  -0.224  -0.381
144   D         0.106   0.256  -0.149   0.281   0.485  -0.090   0.086   0.298  -0.335
145   F         0.106   0.256  -0.149   0.410   0.615  -0.116   0.086   0.298  -0.335
146   V        -1.815  -1.779  -1.585  -1.776  -1.637  -1.366  -1.692  -1.586  -1.332
147   V         0.106   0.256  -0.149   0.124   0.330  -0.252   0.086   0.298  -0.335
148   V         1.015   1.069   1.116   0.939   1.016   1.108   1.055   1.125   1.200
149   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
150   E         1.015   1.069   1.116   0.991   1.062   1.152   1.055   1.125   1.200
151   L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
152   V        -0.311  -0.397  -0.244  -0.473  -0.618  -0.377  -0.561  -0.713  -0.498
153   G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
154   G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
155   I         0.106  -0.101  -0.176   0.265   0.023  -0.091   0.086  -0.224  -0.381
156   Y         1.015   1.069   1.116   1.332   1.385   1.439   1.055   1.125   1.200
157   F         1.015   1.069   1.116   1.277   1.345   1.393   1.055   1.125   1.200
158   G         1.015   1.069   1.116   0.934   1.006   1.104   1.055   1.125   1.200
159   K        -0.750  -0.682  -0.969  -0.613  -0.522  -0.958  -0.722  -0.630  -0.979
160   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
161   K        -1.376  -1.233  -1.036  -1.409  -1.167  -0.903  -1.530  -1.309  -1.061
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   E         1.015   1.069   1.116   0.991   1.062   1.152   1.055   1.125   1.200
166   D        -0.311  -0.135  -0.201  -0.386  -0.090  -0.262  -0.561  -0.278  -0.423
167   D        -1.103  -1.206  -1.021  -1.126  -1.234  -0.973  -1.207  -1.276  -1.044
168   G        -0.311  -0.135  -0.201  -0.486  -0.205  -0.325  -0.561  -0.278  -0.423
169   D        -1.376  -1.233  -1.036  -1.559  -1.329  -1.061  -1.530  -1.309  -1.061
170   G        -0.750  -0.506  -0.961  -0.625  -0.298  -0.898  -0.722  -0.394  -0.969
171   V        -1.376  -1.233  -1.036  -1.450  -1.134  -0.903  -1.530  -1.309  -1.061
172   A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
173   W        -0.750  -1.035  -1.010  -0.156  -0.538  -0.566  -0.722  -1.059  -1.029
174   D         1.015   1.069   1.116   1.071   1.151   1.219   1.055   1.125   1.200
175   S        -0.499  -0.274  -0.210  -0.731  -0.310  -0.264  -0.884  -0.503  -0.439
176   E         0.106  -0.101  -0.176   0.231  -0.019  -0.118   0.086  -0.224  -0.381
177   Q        -1.103  -0.997  -1.021  -1.070  -0.967  -0.912  -1.207  -1.092  -1.044
178   Y         1.015   1.069   1.116   1.332   1.385   1.439   1.055   1.125   1.200
179   T        -0.311  -0.104  -0.204  -0.422  -0.087  -0.277  -0.561  -0.228  -0.428
180   V        -1.542  -1.672  -1.586  -1.457  -1.704  -1.560  -1.368  -1.470  -1.331
181   P        -1.815  -1.747  -1.582  -1.853  -1.775  -1.551  -1.692  -1.555  -1.329
182   E         1.015   1.069   1.116   0.991   1.062   1.152   1.055   1.125   1.200
183   V         0.106   0.007  -0.167   0.124   0.005  -0.285   0.086  -0.057  -0.367
184   Q        -1.815  -1.871  -1.598  -1.596  -1.702  -1.385  -1.692  -1.656  -1.343
185   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
186   I         1.015   1.069   1.116   1.025   1.108   1.181   1.055   1.125   1.200
187   T        -0.311  -0.397  -0.244  -0.439  -0.663  -0.457  -0.561  -0.713  -0.498
188   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
189   M        -0.311  -0.397  -0.244  -0.258  -0.545  -0.363  -0.561  -0.713  -0.498
190   A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
191   A         0.106   0.007  -0.167  -0.037  -0.142  -0.435   0.086  -0.057  -0.367
192   F         0.106  -0.101  -0.176   0.513   0.249   0.087   0.086  -0.224  -0.381
193   M        -0.499  -0.412  -0.238  -0.717  -0.662  -0.394  -0.884  -0.740  -0.488
194   A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
195   L         0.106  -0.101  -0.176  -0.119  -0.392  -0.494   0.086  -0.224  -0.381
196   Q        -0.750  -1.035  -1.010  -0.362  -0.802  -0.924  -0.722  -1.059  -1.029
197   H        -1.542  -1.610  -1.583  -1.023  -1.210  -1.217  -1.368  -1.417  -1.329
198   E         0.106   0.325  -0.145   0.357   0.635  -0.076   0.086   0.390  -0.330
199   P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
200   P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
201   L        -0.311  -0.397  -0.244  -0.820  -0.987  -0.715  -0.561  -0.713  -0.498
202   P         0.106   0.007  -0.167   0.251   0.128  -0.188   0.086  -0.057  -0.367
203   I        -0.311  -0.397  -0.244  -0.450  -0.639  -0.415  -0.561  -0.713  -0.498
204   W         0.106  -0.101  -0.176   0.542   0.239   0.033   0.086  -0.224  -0.381
205   S         0.106  -0.101  -0.176   0.125  -0.195  -0.400   0.086  -0.224  -0.381
206   L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
207   D         1.015   1.069   1.116   1.071   1.151   1.219   1.055   1.125   1.200
208   K         1.015   1.069   1.116   1.027   1.103   1.183   1.055   1.125   1.200
209   A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
210   N         1.015   1.069   1.116   1.178   1.245   1.310   1.055   1.125   1.200
211   V         1.015   1.069   1.116   0.939   1.016   1.108   1.055   1.125   1.200
212   L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
213   A         1.015   1.069   1.116   0.794   0.894   0.987   1.055   1.125   1.200
214   S        -0.311  -0.397  -0.244  -0.422  -0.572  -0.343  -0.561  -0.713  -0.498
215   S         1.015   1.069   1.116   0.993   1.073   1.154   1.055   1.125   1.200
216   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
217   L         1.015   1.069   1.116   0.702   0.791   0.909   1.055   1.125   1.200
218   W         1.015   1.069   1.116   1.349   1.406   1.453   1.055   1.125   1.200
219   R         1.015   1.069   1.116   1.206   1.270   1.333   1.055   1.125   1.200
220   K         0.106   0.269  -0.149   0.223   0.442  -0.158   0.086   0.316  -0.336
221   T         1.015   1.069   1.116   1.092   1.169   1.237   1.055   1.125   1.200
222   V         1.015   1.069   1.116   0.939   1.016   1.108   1.055   1.125   1.200
223   E        -1.815  -1.871  -1.598  -1.865  -1.945  -1.567  -1.692  -1.656  -1.343
224   E        -1.211  -1.151  -1.008  -1.371  -1.210  -1.017  -1.368  -1.216  -1.027
225   T        -1.211  -1.215  -1.014  -1.371  -1.333  -1.049  -1.368  -1.289  -1.034
226   I        -0.750  -0.825  -0.982  -0.481  -0.565  -0.755  -0.722  -0.815  -0.994
227   K        -0.499  -0.405  -0.244  -0.785  -0.623  -0.382  -0.884  -0.726  -0.499
228   N        -1.815  -1.580  -1.569  -1.741  -1.402  -1.385  -1.692  -1.382  -1.316
229   E         1.015   1.069   1.116   0.991   1.062   1.152   1.055   1.125   1.200
230   F         0.106  -0.101  -0.176   0.510   0.243   0.081   0.086  -0.224  -0.381
231   P         1.015   1.069   1.116   1.066   1.142   1.215   1.055   1.125   1.200
232   T        -2.058  -1.986  -2.002  -1.502  -1.536  -1.568  -1.666  -1.596  -1.488
233   L         0.180  -0.288  -0.140  -0.007  -0.637  -0.397   0.189  -0.527  -0.320
234   K        -2.058  -1.942  -1.996  -1.670  -1.630  -1.647  -1.666  -1.560  -1.483
235   V        -1.673  -1.706  -1.582  -1.805  -1.847  -1.667  -1.543  -1.543  -1.329
236   Q        -0.980  -1.029  -1.002  -0.718  -0.920  -0.892  -1.048  -1.116  -1.023
237   H        -0.616  -1.034  -0.972  -0.090  -0.773  -0.699  -0.553  -1.094  -0.982
238   Q         0.180  -0.288  -0.140   0.579  -0.108   0.060   0.189  -0.527  -0.320
239   L         0.180  -0.288  -0.140  -0.015  -0.668  -0.420   0.189  -0.527  -0.320
240   I         0.180  -0.288  -0.140   0.320  -0.333  -0.137   0.189  -0.527  -0.320
241   D         1.015   1.069   1.116   1.076   1.161   1.223   1.055   1.125   1.200
242   S         1.015   1.069   1.116   0.984   1.045   1.146   1.055   1.125   1.200
243   A         0.180  -0.288  -0.140   0.065  -0.608  -0.358   0.189  -0.527  -0.320
244   A         0.180  -0.288  -0.140   0.065  -0.608  -0.358   0.189  -0.527  -0.320
245   M         0.180  -0.288  -0.140   0.590  -0.129   0.052   0.189  -0.527  -0.320
246   I        -0.980  -1.256  -1.018  -1.085  -1.551  -1.246  -1.048  -1.336  -1.040
247   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
248   V        -0.616  -0.843  -0.942  -0.547  -1.044  -1.088  -0.553  -0.908  -0.945
249   K        -0.980  -1.111  -0.978  -0.884  -1.144  -0.894  -1.048  -1.174  -0.991
250   N        -1.145  -1.281  -0.999  -1.177  -1.396  -0.974  -1.295  -1.365  -1.020
251   P         0.180  -0.288  -0.140   0.352  -0.323  -0.118   0.189  -0.527  -0.320
252   T        -0.980  -1.256  -1.018  -0.772  -1.086  -0.795  -1.048  -1.336  -1.040
253   H        -2.297  -2.230  -2.032  -1.978  -1.772  -1.618  -1.914  -1.761  -1.511
254   L         0.180  -0.288  -0.140  -0.027  -0.703  -0.453   0.189  -0.527  -0.320
255   N         0.180  -0.288  -0.140   0.465  -0.223  -0.034   0.189  -0.527  -0.320
256   G         0.180  -0.288  -0.140   0.206  -0.497  -0.256   0.189  -0.527  -0.320
257   I        -0.521  -0.291  -0.210  -0.871  -0.463  -0.356  -0.924  -0.532  -0.439
258   I        -0.451  -0.308  -0.244  -0.713  -0.442  -0.410  -0.800  -0.560  -0.498
259   I        -0.616  -1.034  -0.972  -0.492  -1.217  -1.177  -0.553  -1.094  -0.982
260   T         0.180  -0.288  -0.140   0.367  -0.342  -0.132   0.189  -0.527  -0.320
261   S        -1.673  -1.718  -1.561  -1.603  -1.781  -1.471  -1.543  -1.526  -1.308
262   N         0.180  -0.288  -0.140   0.447  -0.279  -0.083   0.189  -0.527  -0.320
263   M        -0.980  -1.256  -1.018  -0.800  -1.321  -1.041  -1.048  -1.336  -1.040
264   F         0.180  -0.288  -0.140   0.542  -0.204  -0.009   0.189  -0.527  -0.320
265   G         0.180  -0.288  -0.140   0.167  -0.609  -0.366   0.189  -0.527  -0.320
266   D         0.180  -0.288  -0.140   0.352  -0.342  -0.136   0.189  -0.527  -0.320
267   I         0.180  -0.288  -0.140   0.305  -0.390  -0.180   0.189  -0.527  -0.320
268   I         0.180  -0.288  -0.140   0.298  -0.404  -0.198   0.189  -0.527  -0.320
269   S         0.180  -0.288  -0.140   0.229  -0.542  -0.294   0.189  -0.527  -0.320
270   D         1.015   1.069   1.116   1.071   1.151   1.219   1.055   1.125   1.200
271   E         1.015   1.069   1.116   0.986   1.057   1.148   1.055   1.125   1.200
272   A         1.015   1.069   1.116   0.789   0.875   0.982   1.055   1.125   1.200
273   S         1.015   1.069   1.116   0.984   1.045   1.146   1.055   1.125   1.200
274   V         1.015   1.069   1.116   0.938   1.012   1.107   1.055   1.125   1.200
275   I         1.015   1.069   1.116   1.032   1.126   1.187   1.055   1.125   1.200
276   P         1.015   1.069   1.116   1.067   1.142   1.216   1.055   1.125   1.200
277   G         1.015   1.069   1.116   0.933   1.005   1.103   1.055   1.125   1.200
278   S         1.015   1.069   1.116   0.984   1.045   1.146   1.055   1.125   1.200
279   L         0.180   0.269  -0.117  -0.012   0.143  -0.375   0.189   0.316  -0.282
280   G         1.015   1.069   1.116   0.933   1.005   1.103   1.055   1.125   1.200
281   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
282   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
283   P         1.015   1.069   1.116   1.067   1.142   1.216   1.055   1.125   1.200
284   S         1.015   1.069   1.116   0.984   1.045   1.146   1.055   1.125   1.200
285   A         1.015   1.069   1.116   0.789   0.875   0.982   1.055   1.125   1.200
286   S         1.015   1.069   1.116   0.984   1.045   1.146   1.055   1.125   1.200
287   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
288   A        -0.616  -0.567  -0.958  -0.669  -0.582  -1.158  -0.553  -0.470  -0.965
289   S        -0.232  -0.173  -0.226  -0.352  -0.278  -0.404  -0.429  -0.338  -0.466
290   L        -0.616  -0.567  -0.958  -0.740  -0.632  -1.193  -0.553  -0.470  -0.965
291   P         0.180   0.189  -0.122   0.332   0.358  -0.139   0.189   0.207  -0.291
292   D         0.180   0.189  -0.122   0.341   0.377  -0.134   0.189   0.207  -0.291
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   K        -1.145  -0.972  -0.997  -1.222  -0.891  -0.985  -1.295  -1.004  -1.018
296   N        -0.616  -0.567  -0.958  -0.275  -0.193  -0.875  -0.553  -0.470  -0.965
297   T        -1.768  -1.694  -1.561  -1.758  -1.684  -1.451  -1.666  -1.530  -1.310
298   A        -0.616  -0.567  -0.958  -0.602  -0.516  -1.000  -0.553  -0.470  -0.965
299   F        -0.616  -0.567  -0.958  -0.087  -0.010  -0.593  -0.553  -0.470  -0.965
300   G         0.180   0.189  -0.122   0.260   0.289  -0.084   0.189   0.207  -0.291
301   L         0.180   0.269  -0.117  -0.012   0.143  -0.375   0.189   0.316  -0.282
302   Y         0.180   0.189  -0.122   0.601   0.612   0.070   0.189   0.207  -0.291
303   E         1.015   1.069   1.116   0.986   1.057   1.148   1.055   1.125   1.200
304   P         1.015   1.069   1.116   1.067   1.142   1.216   1.055   1.125   1.200
305   C        -0.232  -0.173  -0.226   0.035   0.109  -0.098  -0.429  -0.338  -0.466
306   H         1.015   1.069   1.116   1.325   1.393   1.433   1.055   1.125   1.200
307   G         1.015   1.069   1.116   0.933   1.005   1.103   1.055   1.125   1.200
308   S         1.015   1.069   1.116   0.984   1.045   1.146   1.055   1.125   1.200
309   A         1.015   1.069   1.116   0.789   0.875   0.982   1.055   1.125   1.200
310   P         1.015   1.069   1.116   1.067   1.142   1.216   1.055   1.125   1.200
311   D         1.015   1.069   1.116   1.076   1.161   1.223   1.055   1.125   1.200
312   L        -0.232  -0.173  -0.226  -0.587  -0.462  -0.543  -0.429  -0.338  -0.466
313   P        -2.058  -2.100  -2.026  -1.810  -2.017  -1.898  -1.666  -1.675  -1.507
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   K        -0.980  -0.478  -0.941  -1.066  -0.310  -1.030  -1.048  -0.380  -0.946
316   N        -1.145  -1.287  -1.001  -1.134  -1.225  -0.884  -1.295  -1.372  -1.021
317   K        -0.232  -0.173  -0.226  -0.293  -0.205  -0.333  -0.429  -0.338  -0.466
318   V         1.015   1.069   1.116   0.938   1.012   1.107   1.055   1.125   1.200
319   N         1.015   1.069   1.116   1.182   1.261   1.312   1.055   1.125   1.200
320   P         1.015   1.069   1.116   1.067   1.142   1.216   1.055   1.125   1.200
321   I        -0.521  -0.397  -0.243  -0.871  -0.625  -0.413  -0.924  -0.712  -0.497
322   A        -0.232  -0.173  -0.226  -0.543  -0.444  -0.542  -0.429  -0.338  -0.466
323   T         1.015   1.069   1.116   1.094   1.171   1.239   1.055   1.125   1.200
324   I         1.015   1.069   1.116   1.032   1.126   1.187   1.055   1.125   1.200
325   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
326   S         1.015   1.069   1.116   0.984   1.045   1.146   1.055   1.125   1.200
327   A        -0.232  -0.031  -0.209  -0.542  -0.217  -0.510  -0.429  -0.115  -0.437
328   A         0.180   0.189  -0.122   0.061   0.096  -0.340   0.189   0.207  -0.291
329   M        -0.616  -0.414  -0.921  -0.180   0.066  -0.785  -0.553  -0.295  -0.919
330   M         0.180   0.189  -0.122   0.547   0.556  -0.028   0.189   0.207  -0.291
331   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
332   K        -0.521  -0.402  -0.243  -0.680  -0.487  -0.245  -0.924  -0.721  -0.496
333   L        -0.980  -1.256  -1.018  -1.080  -1.289  -0.939  -1.048  -1.336  -1.040
334   S         0.180   0.189  -0.122   0.249   0.260  -0.206   0.189   0.207  -0.291
335   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
336   N        -0.521  -0.286  -0.211  -0.662  -0.211  -0.164  -0.924  -0.523  -0.441
337   L        -1.673  -1.752  -1.574  -1.711  -1.677  -1.471  -1.543  -1.555  -1.321
338   P        -1.768  -1.672  -1.561  -1.753  -1.637  -1.374  -1.666  -1.518  -1.309
339   E        -1.384  -1.230  -1.023  -1.614  -1.338  -1.048  -1.543  -1.309  -1.045
340   E         0.180  -0.288  -0.140   0.231  -0.530  -0.292   0.189  -0.527  -0.320
341   G        -0.521  -0.402  -0.243  -1.056  -0.826  -0.569  -0.924  -0.721  -0.496
342   K        -1.673  -1.336  -1.547  -1.568  -1.187  -1.362  -1.543  -1.231  -1.299
343   A         0.180   0.482  -0.097   0.068   0.439  -0.279   0.189   0.586  -0.249
344   I        -1.384  -1.218  -1.035  -1.852  -1.498  -1.258  -1.543  -1.290  -1.059
345   E         1.015   1.069   1.116   0.986   1.057   1.148   1.055   1.125   1.200
346   D        -2.297  -1.538  -1.977  -2.310  -1.285  -1.785  -1.914  -1.126  -1.469
347   A         1.015   1.069   1.116   0.789   0.875   0.982   1.055   1.125   1.200
348   V         1.015   1.069   1.116   0.938   1.012   1.107   1.055   1.125   1.200
349   K        -0.980  -0.639  -0.968  -0.912  -0.441  -0.902  -1.048  -0.604  -0.982
350   K        -2.297  -2.113  -2.015  -2.071  -1.902  -1.716  -1.914  -1.690  -1.498
351   V        -0.616  -0.974  -0.962  -0.543  -1.126  -1.115  -0.553  -1.033  -0.971
352   L        -0.616  -0.974  -0.962  -0.740  -1.275  -1.200  -0.553  -1.033  -0.971
353   D         0.180  -0.288  -0.140   0.348  -0.351  -0.146   0.189  -0.527  -0.320
354   A        -1.768  -1.579  -1.569  -1.929  -1.613  -1.538  -1.666  -1.379  -1.318
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   G         1.015   1.069   1.116   0.933   1.005   1.103   1.055   1.125   1.200
362   I        -1.364  -1.089  -1.537  -1.164  -0.774  -1.526  -1.172  -0.843  -1.285
363   R        -1.364  -1.650  -1.578  -0.847  -1.291  -1.213  -1.172  -1.468  -1.324
364   T         1.015   1.069   1.116   1.094   1.171   1.239   1.055   1.125   1.200
365   G        -1.768  -1.563  -1.563  -1.974  -1.609  -1.568  -1.666  -1.360  -1.311
366   D         1.015   1.069   1.116   1.076   1.161   1.223   1.055   1.125   1.200
367   L         0.180  -0.288  -0.140  -0.012  -0.645  -0.411   0.189  -0.527  -0.320
368   G        -0.980  -0.474  -0.932  -0.971  -0.289  -0.885  -1.048  -0.386  -0.934
369   G         1.015   1.069   1.116   0.933   1.005   1.103   1.055   1.125   1.200
370   S        -1.673  -1.406  -1.556  -1.576  -1.163  -1.388  -1.543  -1.174  -1.304
371   N        -1.384  -1.156  -1.028  -1.622  -1.289  -1.123  -1.543  -1.212  -1.051
372   S         0.180   0.269  -0.117   0.272   0.384  -0.136   0.189   0.316  -0.282
373   T         1.015   1.069   1.116   1.094   1.171   1.239   1.055   1.125   1.200
374   T        -1.673  -1.533  -1.567  -1.609  -1.494  -1.537  -1.543  -1.372  -1.315
375   E        -0.232  -0.173  -0.226  -0.303  -0.211  -0.328  -0.429  -0.338  -0.466
376   V        -0.616  -0.567  -0.958  -0.446  -0.364  -0.879  -0.553  -0.470  -0.965
377   G         0.180   0.189  -0.122   0.221   0.248  -0.185   0.189   0.207  -0.291
378   D        -0.616  -0.567  -0.958  -0.335  -0.245  -0.844  -0.553  -0.470  -0.965
379   A         0.180  -0.288  -0.140   0.105  -0.482  -0.248   0.189  -0.527  -0.320
380   V        -0.451  -0.134  -0.193  -0.747  -0.205  -0.328  -0.800  -0.275  -0.411
381   A        -0.232  -0.173  -0.226  -0.542  -0.441  -0.540  -0.429  -0.338  -0.466
382   E        -1.673  -1.672  -1.554  -1.656  -1.588  -1.491  -1.543  -1.488  -1.302
383   E        -1.768  -1.693  -1.561  -1.966  -1.806  -1.562  -1.666  -1.528  -1.309
384   V        -0.232  -0.173  -0.226  -0.469  -0.377  -0.556  -0.429  -0.338  -0.466
385   K        -1.673  -1.257  -1.556  -1.566  -1.051  -1.371  -1.543  -1.093  -1.305
386   K        -0.451  -0.416  -0.237  -0.706  -0.677  -0.379  -0.800  -0.746  -0.485
387   I        -0.980  -0.908  -0.981  -1.085  -1.123  -1.167  -1.048  -1.011  -0.998
388   L         1.015   1.069   1.116   0.710   0.811   0.916   1.055   1.125   1.200
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   A        -1.542  -1.494  -1.569  -1.608  -1.604  -1.623  -1.368  -1.345  -1.315
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P04173
Output conservation file - output/P04173
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
