1     M         1.011   1.039   1.091   1.192   1.228   1.296   1.069   1.106   1.184
2     C         1.011   1.039   1.091   1.206   1.245   1.308   1.069   1.106   1.184
3     G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
4     I         0.324   0.436   0.062   0.355   0.501  -0.046   0.310   0.469  -0.140
5     L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
6     G        -0.015  -0.141  -0.062  -0.246  -0.497  -0.371  -0.232  -0.468  -0.365
7     I        -0.196  -0.202  -0.068  -0.491  -0.535  -0.302  -0.557  -0.580  -0.377
8     V        -2.030  -2.011  -1.894  -1.910  -1.883  -1.700  -1.641  -1.599  -1.413
9     L         0.324   0.442   0.064   0.321   0.475  -0.057   0.310   0.478  -0.137
10    A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
11    N        -0.331  -0.116  -0.614  -0.224   0.058  -0.648  -0.340  -0.055  -0.723
12    Q        -1.517  -1.615  -1.578  -1.187  -1.353  -1.327  -1.316  -1.400  -1.298
13    T        -1.714  -1.731  -1.579  -1.529  -1.551  -1.313  -1.533  -1.508  -1.299
14    T        -1.517  -1.420  -1.545  -1.454  -1.329  -1.497  -1.316  -1.203  -1.270
15    P        -2.149  -2.026  -1.891  -2.055  -1.870  -1.685  -1.750  -1.612  -1.412
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    V        -0.196  -0.202  -0.068  -0.565  -0.599  -0.365  -0.557  -0.580  -0.377
18    A        -0.631  -0.776  -0.717  -0.727  -0.937  -0.799  -0.774  -0.956  -0.864
19    P        -0.631  -0.601  -0.699  -0.595  -0.620  -0.757  -0.774  -0.762  -0.841
20    E         0.324   0.155   0.038   0.377   0.153  -0.055   0.310   0.046  -0.182
21    L         0.324   0.208   0.041   0.321   0.169  -0.099   0.310   0.130  -0.178
22    C        -1.714  -1.756  -1.588  -1.462  -1.506  -1.287  -1.533  -1.525  -1.306
23    D        -0.253  -0.178  -0.060  -0.573  -0.433  -0.244  -0.666  -0.537  -0.362
24    G         0.324   0.155   0.038   0.283   0.063  -0.123   0.310   0.046  -0.182
25    C        -1.398  -1.312  -1.214  -1.430  -1.346  -1.177  -1.424  -1.307  -1.147
26    I        -1.398  -1.265  -1.208  -1.366  -1.178  -1.108  -1.424  -1.270  -1.142
27    F        -0.331  -0.600  -0.677  -0.105  -0.488  -0.640  -0.340  -0.699  -0.807
28    L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
29    Q         1.011   1.039   1.091   1.129   1.162   1.240   1.069   1.106   1.184
30    H         1.011   1.039   1.091   1.210   1.242   1.312   1.069   1.106   1.184
31    R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
32    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
33    Q         1.011   1.039   1.091   1.129   1.162   1.240   1.069   1.106   1.184
34    D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
35    A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
36    A        -0.015  -0.080  -0.053  -0.137  -0.240  -0.174  -0.232  -0.357  -0.349
37    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
38    I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
39    A        -0.766  -0.666  -0.700  -1.069  -0.933  -0.912  -0.991  -0.866  -0.845
40    T         1.011   1.039   1.091   1.118   1.152   1.230   1.069   1.106   1.184
41    C        -0.331  -0.413  -0.654  -0.022  -0.151  -0.587  -0.340  -0.450  -0.776
42    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
43    S        -0.947  -0.944  -1.157  -0.729  -0.741  -1.030  -0.882  -0.875  -1.087
44    R        -0.631  -0.777  -0.709  -0.687  -0.918  -0.827  -0.774  -0.948  -0.854
45    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
46    R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
47    I        -0.963  -0.861  -0.731  -1.237  -1.089  -0.863  -1.208  -1.065  -0.880
48    Y         0.324   0.155   0.038   0.499   0.276   0.073   0.310   0.046  -0.182
49    Q         1.011   1.039   1.091   1.129   1.162   1.240   1.069   1.106   1.184
50    C         1.011   1.039   1.091   1.206   1.245   1.308   1.069   1.106   1.184
51    K         1.011   1.039   1.091   1.073   1.119   1.191   1.069   1.106   1.184
52    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
53    N         0.324   0.208   0.041   0.427   0.286  -0.000   0.310   0.130  -0.178
54    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
55    M         1.011   1.039   1.091   1.192   1.228   1.296   1.069   1.106   1.184
56    A        -0.015  -0.051  -0.046  -0.233  -0.309  -0.322  -0.232  -0.305  -0.337
57    R        -0.331  -0.600  -0.677  -0.247  -0.647  -0.802  -0.340  -0.699  -0.807
58    D         0.324   0.155   0.038   0.384   0.167  -0.025   0.310   0.046  -0.182
59    V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
60    F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
61    T        -0.331  -0.600  -0.677  -0.095  -0.496  -0.664  -0.340  -0.699  -0.807
62    Q         0.324   0.155   0.038   0.517   0.277   0.059   0.310   0.046  -0.182
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    Q        -0.947  -1.155  -1.189  -0.598  -0.905  -0.959  -0.882  -1.118  -1.121
65    R         0.324   0.208   0.041   0.388   0.243  -0.002   0.310   0.130  -0.178
66    V        -1.279  -1.381  -1.205  -1.276  -1.396  -1.146  -1.316  -1.367  -1.139
67    S        -2.149  -2.116  -1.905  -2.122  -2.090  -1.787  -1.750  -1.674  -1.421
68    G        -1.201  -1.317  -1.202  -1.275  -1.413  -1.228  -1.208  -1.293  -1.135
69    L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
70    A        -0.331  -0.374  -0.645  -0.291  -0.344  -0.753  -0.340  -0.417  -0.764
71    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
72    S        -0.631  -0.672  -0.686  -0.627  -0.659  -0.703  -0.774  -0.797  -0.821
73    M         0.324   0.433   0.064   0.595   0.729   0.199   0.310   0.466  -0.136
74    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
75    I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
76    A        -0.947  -0.890  -1.154  -0.861  -0.820  -1.134  -0.882  -0.815  -1.084
77    H         1.011   1.039   1.091   1.210   1.242   1.312   1.069   1.106   1.184
78    L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
79    R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
80    Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
81    P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
82    T         1.011   1.039   1.091   1.118   1.152   1.230   1.069   1.106   1.184
83    A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
84    G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
85    S         0.324   0.155   0.038   0.424   0.202   0.020   0.310   0.046  -0.182
86    S        -0.331  -0.413  -0.654  -0.145  -0.248  -0.585  -0.340  -0.450  -0.776
87    A         0.324   0.155   0.038   0.288   0.057  -0.119   0.310   0.046  -0.182
88    N        -1.201  -1.317  -1.202  -1.182  -1.311  -1.159  -1.208  -1.293  -1.135
89    S         0.324   0.155   0.038   0.393   0.150  -0.066   0.310   0.046  -0.182
90    E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
91    A         0.324   0.155   0.038   0.288   0.057  -0.119   0.310   0.046  -0.182
92    Q         1.011   1.039   1.091   1.129   1.162   1.240   1.069   1.106   1.184
93    P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
94    F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
95    Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
96    V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
97    N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
98    S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
99    P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
100   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
101   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
102   I        -0.015  -0.051  -0.046  -0.149  -0.228  -0.252  -0.232  -0.305  -0.337
103   N        -1.398  -1.254  -1.197  -1.394  -1.181  -1.110  -1.424  -1.254  -1.131
104   L        -1.201  -1.190  -1.183  -1.173  -1.154  -1.117  -1.208  -1.173  -1.117
105   A        -0.963  -0.912  -0.748  -1.328  -1.261  -0.986  -1.208  -1.124  -0.900
106   H         1.011   1.039   1.091   1.210   1.242   1.312   1.069   1.106   1.184
107   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
108   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
109   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
110   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
111   V        -0.015  -0.141  -0.062  -0.192  -0.421  -0.302  -0.232  -0.468  -0.365
112   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
113   T        -1.398  -1.391  -1.215  -1.514  -1.550  -1.280  -1.424  -1.377  -1.149
114   A        -1.714  -1.399  -1.554  -1.639  -1.154  -1.422  -1.533  -1.198  -1.278
115   S        -0.963  -0.836  -0.727  -1.288  -1.100  -0.906  -1.208  -1.038  -0.876
116   L         0.324   0.436   0.062   0.321   0.467  -0.061   0.310   0.469  -0.140
117   K        -0.631  -0.395  -0.653  -0.642  -0.297  -0.650  -0.774  -0.438  -0.777
118   R        -1.517  -1.474  -1.562  -1.350  -1.319  -1.431  -1.316  -1.262  -1.285
119   Y        -0.331  -0.359  -0.644  -0.066  -0.115  -0.510  -0.340  -0.384  -0.763
120   M        -0.196  -0.049  -0.021  -0.390  -0.159  -0.108  -0.557  -0.302  -0.289
121   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
122   E        -0.947  -1.155  -1.189  -0.748  -1.037  -1.078  -0.882  -1.118  -1.121
123   D        -1.714  -1.572  -1.580  -1.727  -1.531  -1.523  -1.533  -1.382  -1.301
124   V        -0.015  -0.141  -0.062  -0.218  -0.465  -0.350  -0.232  -0.468  -0.365
125   H         1.011   1.039   1.091   1.210   1.242   1.312   1.069   1.106   1.184
126   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
127   H         1.011   1.039   1.091   1.210   1.242   1.312   1.069   1.106   1.184
128   I        -0.015  -0.141  -0.062  -0.154  -0.406  -0.294  -0.232  -0.468  -0.365
129   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
130   T         1.011   1.039   1.091   1.118   1.152   1.230   1.069   1.106   1.184
131   D         0.324   0.208   0.041   0.358   0.203  -0.092   0.310   0.130  -0.178
132   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
133   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
134   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
135   E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
136   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
137   L         0.324   0.155   0.038   0.352   0.144  -0.017   0.310   0.046  -0.182
138   L         0.324   0.442   0.064   0.321   0.474  -0.058   0.310   0.478  -0.137
139   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
140   I         0.324   0.155   0.038   0.355   0.119  -0.091   0.310   0.046  -0.182
141   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
142   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
143   A        -0.947  -1.076  -1.174  -0.875  -1.076  -1.188  -0.882  -1.039  -1.105
144   E         0.324   0.155   0.038   0.365   0.131  -0.089   0.310   0.046  -0.182
145   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
146   E        -1.201  -1.260  -1.200  -1.163  -1.251  -1.150  -1.208  -1.260  -1.134
147   K        -0.331  -0.600  -0.677  -0.144  -0.535  -0.709  -0.340  -0.699  -0.807
148   H        -1.714  -1.741  -1.586  -1.452  -1.520  -1.304  -1.533  -1.516  -1.305
149   N        -0.631  -0.794  -0.717  -0.669  -0.937  -0.857  -0.774  -0.973  -0.864
150   K         1.011   1.039   1.091   1.073   1.119   1.191   1.069   1.106   1.184
151   Y        -1.714  -1.771  -1.595  -1.646  -1.754  -1.512  -1.533  -1.538  -1.312
152   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
153   V        -0.015  -0.051  -0.046  -0.192  -0.253  -0.273  -0.232  -0.305  -0.337
154   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
155   N        -0.947  -1.155  -1.189  -0.743  -1.046  -1.127  -0.882  -1.118  -1.121
156   E        -1.714  -1.652  -1.575  -1.712  -1.632  -1.498  -1.533  -1.452  -1.297
157   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
158   V        -0.885  -0.663  -0.690  -1.157  -0.770  -0.854  -1.099  -0.786  -0.825
159   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
160   H        -1.714  -1.681  -1.581  -1.516  -1.518  -1.383  -1.533  -1.473  -1.302
161   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
162   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
163   E        -1.714  -1.685  -1.582  -1.680  -1.643  -1.482  -1.533  -1.476  -1.302
164   G        -0.331  -0.600  -0.677  -0.303  -0.665  -0.787  -0.340  -0.699  -0.807
165   V        -0.196  -0.169  -0.065  -0.444  -0.395  -0.222  -0.557  -0.520  -0.372
166   Y        -0.015   0.119   0.005   0.050   0.249   0.058  -0.232  -0.014  -0.243
167   R        -1.201  -1.232  -1.196  -1.236  -1.305  -1.228  -1.208  -1.231  -1.131
168   L        -1.714  -1.572  -1.580  -1.734  -1.546  -1.498  -1.533  -1.382  -1.301
169   C        -0.631  -0.630  -0.683  -0.504  -0.483  -0.654  -0.774  -0.741  -0.817
170   R        -0.331  -0.600  -0.677  -0.205  -0.574  -0.699  -0.340  -0.699  -0.807
171   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
172   G        -0.196  -0.100  -0.050  -0.590  -0.413  -0.346  -0.557  -0.392  -0.344
173   Y         0.324   0.155   0.038   0.531   0.328   0.158   0.310   0.046  -0.182
174   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
175   C         0.324   0.155   0.038   0.584   0.346   0.098   0.310   0.046  -0.182
176   V        -0.015  -0.080  -0.053  -0.145  -0.245  -0.207  -0.232  -0.357  -0.349
177   G        -0.253  -0.178  -0.060  -0.712  -0.576  -0.366  -0.666  -0.537  -0.362
178   L        -0.015   0.166   0.017   0.060   0.347   0.049  -0.232   0.063  -0.222
179   L        -0.885  -0.879  -0.746  -1.176  -1.177  -0.967  -1.099  -1.085  -0.899
180   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
181   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
182   F        -0.766  -0.787  -0.710  -0.815  -0.829  -0.728  -0.991  -0.974  -0.856
183   A        -0.196  -0.049  -0.021  -0.590  -0.316  -0.286  -0.557  -0.302  -0.289
184   L        -1.279  -1.238  -1.193  -1.408  -1.347  -1.218  -1.316  -1.240  -1.128
185   F        -0.766  -0.812  -0.712  -0.911  -0.967  -0.804  -0.991  -1.012  -0.858
186   G         0.324   0.155   0.038   0.265   0.033  -0.172   0.310   0.046  -0.182
187   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
188   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
189   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
190   P         0.324   0.155   0.038   0.526   0.300   0.106   0.310   0.046  -0.182
191   N        -0.331  -0.459  -0.658  -0.126  -0.295  -0.574  -0.340  -0.518  -0.783
192   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
193   I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
194   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
195   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
196   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
197   L        -0.631  -0.794  -0.717  -0.774  -1.036  -0.926  -0.774  -0.973  -0.864
198   F        -0.947  -1.155  -1.189  -0.697  -1.006  -1.106  -0.882  -1.118  -1.121
199   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
200   E        -0.631  -0.606  -0.699  -0.656  -0.660  -0.751  -0.774  -0.767  -0.842
201   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
202   E        -2.465  -2.235  -2.150  -2.291  -1.936  -1.876  -1.858  -1.649  -1.488
203   N        -0.631  -0.776  -0.717  -0.613  -0.835  -0.747  -0.774  -0.956  -0.864
204   P        -1.833  -1.688  -1.582  -1.890  -1.675  -1.505  -1.641  -1.483  -1.303
205   D        -1.398  -1.386  -1.212  -1.458  -1.412  -1.168  -1.424  -1.372  -1.146
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
209   T        -1.679  -1.661  -1.584  -1.526  -1.572  -1.466  -1.480  -1.446  -1.304
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   K        -0.015  -0.053  -0.048  -0.041  -0.118  -0.161  -0.232  -0.308  -0.340
212   D         0.324   0.433   0.064   0.376   0.520  -0.001   0.310   0.466  -0.136
213   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
214   M         1.011   1.039   1.091   1.192   1.228   1.296   1.069   1.106   1.184
215   L        -0.015  -0.080  -0.053  -0.140  -0.253  -0.212  -0.232  -0.357  -0.349
216   A         0.324   0.373   0.058   0.288   0.352  -0.085   0.310   0.381  -0.148
217   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
218   E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
219   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
220   V         0.324   0.155   0.038   0.305   0.087  -0.116   0.310   0.046  -0.182
221   V        -0.015  -0.080  -0.053  -0.218  -0.342  -0.332  -0.232  -0.357  -0.349
222   F         0.324   0.469   0.066   0.337   0.519  -0.014   0.310   0.516  -0.134
223   K        -1.517  -1.591  -1.575  -1.238  -1.381  -1.355  -1.316  -1.380  -1.296
224   A        -0.015  -0.141  -0.062  -0.163  -0.378  -0.228  -0.232  -0.468  -0.365
225   H        -1.201  -1.236  -1.198  -1.008  -1.131  -1.053  -1.208  -1.239  -1.133
226   N        -0.015   0.137   0.008  -0.200   0.045  -0.168  -0.232   0.017  -0.236
227   F         0.324   0.208   0.041   0.492   0.344   0.074   0.310   0.130  -0.178
228   T        -1.714  -1.739  -1.583  -1.599  -1.654  -1.440  -1.533  -1.515  -1.303
229   K        -1.714  -1.684  -1.576  -1.605  -1.559  -1.415  -1.533  -1.475  -1.298
230   Y        -0.331  -0.172  -0.621  -0.057   0.140  -0.445  -0.340  -0.130  -0.732
231   R        -1.201  -1.181  -1.179  -1.226  -1.173  -1.165  -1.208  -1.159  -1.113
232   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
233   L        -0.963  -0.826  -0.724  -1.320  -1.077  -0.926  -1.208  -1.017  -0.872
234   K        -0.331  -0.600  -0.677  -0.153  -0.552  -0.731  -0.340  -0.699  -0.807
235   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
236   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
237   E        -0.015  -0.038  -0.046  -0.073  -0.112  -0.139  -0.232  -0.282  -0.337
238   A         0.324   0.208   0.041   0.316   0.175  -0.039   0.310   0.130  -0.178
239   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
240   I        -0.015  -0.141  -0.062  -0.098  -0.324  -0.195  -0.232  -0.468  -0.365
241   I         0.324   0.436   0.062   0.355   0.501  -0.046   0.310   0.469  -0.140
242   P        -1.517  -1.621  -1.576  -1.207  -1.399  -1.348  -1.316  -1.405  -1.297
243   K         0.324   0.208   0.041   0.461   0.311   0.017   0.310   0.130  -0.178
244   N        -1.714  -1.651  -1.573  -1.697  -1.611  -1.482  -1.533  -1.451  -1.296
245   C        -0.913  -0.753  -0.732  -0.946  -0.720  -0.679  -1.151  -0.933  -0.880
246   S        -1.419  -1.374  -1.226  -1.483  -1.446  -1.209  -1.429  -1.362  -1.159
247   K        -0.913  -0.844  -0.732  -1.110  -1.001  -0.835  -1.151  -1.040  -0.881
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   G        -0.947  -0.888  -1.146  -0.876  -0.795  -1.145  -0.882  -0.813  -1.076
257   E        -1.517  -1.547  -1.563  -1.352  -1.417  -1.444  -1.316  -1.341  -1.286
258   P        -0.331  -0.359  -0.644  -0.089  -0.150  -0.592  -0.340  -0.384  -0.763
259   E        -0.947  -1.155  -1.189  -0.773  -1.068  -1.128  -0.882  -1.118  -1.121
260   F         0.324   0.208   0.041   0.481   0.327   0.044   0.310   0.130  -0.178
261   K        -0.631  -0.658  -0.684  -0.626  -0.628  -0.669  -0.774  -0.778  -0.820
262   Q         1.011   1.039   1.091   1.129   1.162   1.240   1.069   1.106   1.184
263   V         0.324   0.208   0.041   0.305   0.165  -0.112   0.310   0.130  -0.178
264   V         0.324   0.208   0.041   0.299   0.157  -0.129   0.310   0.130  -0.178
265   P        -0.196  -0.169  -0.065  -0.337  -0.310  -0.161  -0.557  -0.520  -0.372
266   I        -2.149  -1.974  -1.891  -1.856  -1.607  -1.505  -1.750  -1.575  -1.411
267   N        -1.279  -1.268  -1.197  -1.311  -1.270  -1.182  -1.316  -1.262  -1.130
268   S        -1.517  -1.578  -1.574  -1.358  -1.520  -1.497  -1.316  -1.368  -1.295
269   Y        -0.196  -0.154  -0.062  -0.304  -0.242  -0.113  -0.557  -0.492  -0.366
270   R        -1.398  -1.409  -1.218  -1.537  -1.527  -1.235  -1.424  -1.393  -1.151
271   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
272   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
273   L        -0.196  -0.049  -0.021  -0.491  -0.224  -0.199  -0.557  -0.302  -0.289
274   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
275   E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
276   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
277   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
278   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
279   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
280   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
281   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
282   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
283   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
284   S         0.324   0.155   0.038   0.424   0.202   0.020   0.310   0.046  -0.182
285   V        -0.015  -0.038  -0.046  -0.192  -0.229  -0.273  -0.232  -0.282  -0.337
286   L        -0.631  -0.776  -0.717  -0.667  -0.874  -0.764  -0.774  -0.956  -0.864
287   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
288   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
289   I        -0.631  -0.630  -0.683  -0.741  -0.715  -0.843  -0.774  -0.741  -0.817
290   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
291   V         0.324   0.433   0.064   0.305   0.460  -0.070   0.310   0.466  -0.136
292   Y         0.324   0.155   0.038   0.517   0.304   0.120   0.310   0.046  -0.182
293   H        -0.766  -0.756  -0.696  -0.793  -0.759  -0.649  -0.991  -0.926  -0.835
294   T        -0.253  -0.166  -0.054  -0.454  -0.320  -0.137  -0.666  -0.514  -0.351
295   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
296   L        -0.631  -0.672  -0.686  -0.722  -0.748  -0.777  -0.774  -0.797  -0.821
297   A        -1.398  -1.258  -1.209  -1.609  -1.390  -1.287  -1.424  -1.269  -1.143
298   M         1.011   1.039   1.091   1.192   1.228   1.296   1.069   1.106   1.184
299   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
300   S        -1.714  -1.543  -1.565  -1.802  -1.555  -1.566  -1.533  -1.355  -1.289
301   K         1.011   1.039   1.091   1.073   1.119   1.191   1.069   1.106   1.184
302   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
303   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
304   E        -1.201  -1.287  -1.199  -1.126  -1.239  -1.103  -1.208  -1.279  -1.133
305   N        -1.201  -1.232  -1.190  -1.122  -1.169  -1.097  -1.208  -1.231  -1.125
306   I        -0.015  -0.056  -0.050  -0.154  -0.238  -0.269  -0.232  -0.313  -0.344
307   L        -1.714  -1.624  -1.564  -1.605  -1.442  -1.362  -1.533  -1.410  -1.287
308   K        -1.517  -1.474  -1.562  -1.328  -1.292  -1.479  -1.316  -1.262  -1.285
309   Q        -1.517  -1.406  -1.224  -1.652  -1.511  -1.219  -1.533  -1.390  -1.157
310   L        -1.714  -1.509  -1.560  -1.647  -1.383  -1.431  -1.533  -1.329  -1.285
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   K        -1.201  -0.946  -1.155  -1.282  -0.902  -1.190  -1.208  -0.890  -1.086
321   P        -1.714  -1.636  -1.574  -1.691  -1.565  -1.507  -1.533  -1.428  -1.295
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -0.913  -0.833  -0.726  -1.123  -0.996  -0.815  -1.151  -1.035  -0.875
325   -        -1.419  -1.308  -1.205  -1.526  -1.352  -1.186  -1.429  -1.286  -1.137
326   -        -1.419  -1.381  -1.217  -1.518  -1.460  -1.204  -1.429  -1.366  -1.150
327   E        -0.947  -0.932  -1.158  -0.794  -0.782  -1.121  -0.882  -0.871  -1.088
328   D        -0.766  -0.756  -0.696  -0.937  -0.864  -0.775  -0.991  -0.926  -0.835
329   I         0.324   0.436   0.062   0.355   0.501  -0.046   0.310   0.469  -0.140
330   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
331   V         0.324   0.208   0.041   0.293   0.147  -0.144   0.310   0.130  -0.178
332   V         0.324   0.155   0.038   0.305   0.087  -0.116   0.310   0.046  -0.182
333   I         0.324   0.436   0.062   0.355   0.501  -0.046   0.310   0.469  -0.140
334   P         0.324   0.436   0.062   0.510   0.648   0.106   0.310   0.469  -0.140
335   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
336   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
337   D         0.324   0.155   0.038   0.372   0.147  -0.058   0.310   0.046  -0.182
338   T         0.324   0.208   0.041   0.510   0.352   0.068   0.310   0.130  -0.178
339   A        -0.196  -0.180  -0.069  -0.519  -0.506  -0.304  -0.557  -0.539  -0.379
340   R         0.324   0.155   0.038   0.375   0.151  -0.043   0.310   0.046  -0.182
341   T         0.324   0.373   0.058   0.538   0.598   0.168   0.310   0.381  -0.148
342   C        -1.398  -1.248  -1.206  -1.437  -1.281  -1.143  -1.424  -1.257  -1.140
343   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
344   L        -0.331  -0.407  -0.647  -0.280  -0.413  -0.755  -0.340  -0.455  -0.767
345   E        -1.279  -1.380  -1.203  -1.328  -1.491  -1.233  -1.316  -1.366  -1.137
346   C        -0.331  -0.600  -0.677  -0.031  -0.443  -0.657  -0.340  -0.699  -0.807
347   A         0.324   0.155   0.038   0.288   0.057  -0.119   0.310   0.046  -0.182
348   N        -1.279  -1.379  -1.207  -1.375  -1.472  -1.213  -1.316  -1.365  -1.140
349   V        -2.149  -2.020  -1.893  -2.015  -1.806  -1.657  -1.750  -1.611  -1.413
350   L         0.324   0.208   0.041   0.309   0.151  -0.131   0.310   0.130  -0.178
351   G        -1.714  -1.652  -1.578  -1.625  -1.548  -1.442  -1.533  -1.455  -1.300
352   K        -1.201  -1.076  -1.175  -1.190  -1.030  -1.184  -1.208  -1.067  -1.110
353   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
354   Y        -0.015  -0.057  -0.049   0.017  -0.063  -0.086  -0.232  -0.315  -0.341
355   R        -0.331  -0.600  -0.677  -0.243  -0.636  -0.793  -0.340  -0.699  -0.807
356   E        -0.331  -0.365  -0.644  -0.219  -0.276  -0.694  -0.340  -0.406  -0.763
357   G         0.324   0.208   0.041   0.265   0.113  -0.167   0.310   0.130  -0.178
358   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
359   V        -0.196  -0.160  -0.066  -0.520  -0.458  -0.309  -0.557  -0.502  -0.373
360   K         1.011   1.039   1.091   1.073   1.119   1.191   1.069   1.106   1.184
361   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
362   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
363   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
364   V        -0.015  -0.025  -0.044  -0.192  -0.206  -0.269  -0.232  -0.259  -0.332
365   G         0.324   0.155   0.038   0.294   0.083  -0.091   0.310   0.046  -0.182
366   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
367   T         1.011   1.039   1.091   1.118   1.152   1.230   1.069   1.106   1.184
368   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
369   I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
370   M         0.324   0.155   0.038   0.573   0.330   0.093   0.310   0.046  -0.182
371   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
372   N        -0.631  -0.646  -0.709  -0.686  -0.789  -0.858  -0.774  -0.836  -0.854
373   Q         1.011   1.039   1.091   1.129   1.162   1.240   1.069   1.106   1.184
374   R        -0.766  -0.638  -0.701  -0.787  -0.623  -0.684  -0.991  -0.838  -0.846
375   E        -0.331  -0.600  -0.677  -0.243  -0.646  -0.811  -0.340  -0.699  -0.807
376   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
377   V        -1.279  -1.295  -1.200  -1.395  -1.368  -1.194  -1.316  -1.290  -1.134
378   S        -0.015  -0.141  -0.062  -0.064  -0.293  -0.176  -0.232  -0.468  -0.365
379   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
380   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
381   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
382   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
383   K         1.011   1.039   1.091   1.073   1.119   1.191   1.069   1.106   1.184
384   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
385   N         0.324   0.155   0.038   0.427   0.209  -0.005   0.310   0.046  -0.182
386   P        -0.766  -0.815  -0.714  -0.916  -1.006  -0.847  -0.991  -1.016  -0.862
387   M         0.324   0.208   0.041   0.600   0.448   0.170   0.310   0.130  -0.178
388   E        -1.201  -1.164  -1.177  -1.225  -1.132  -1.184  -1.208  -1.129  -1.110
389   S        -0.331  -0.413  -0.654  -0.153  -0.265  -0.604  -0.340  -0.450  -0.776
390   E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
391   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
392   K        -1.517  -1.412  -1.546  -1.279  -1.135  -1.374  -1.316  -1.196  -1.270
393   G        -0.196  -0.197  -0.070  -0.542  -0.550  -0.328  -0.557  -0.572  -0.381
394   K        -0.196  -0.180  -0.069  -0.381  -0.371  -0.208  -0.557  -0.539  -0.379
395   K        -1.714  -1.622  -1.566  -1.679  -1.560  -1.471  -1.533  -1.420  -1.290
396   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
397   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
398   I        -0.253  -0.199  -0.068  -0.619  -0.531  -0.302  -0.666  -0.575  -0.377
399   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
400   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
401   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
402   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
403   I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
404   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
405   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
406   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
407   T         1.011   1.039   1.091   1.118   1.152   1.230   1.069   1.106   1.184
408   T         1.011   1.039   1.091   1.118   1.152   1.230   1.069   1.106   1.184
409   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
410   K        -0.196  -0.197  -0.070  -0.381  -0.413  -0.213  -0.557  -0.572  -0.381
411   E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
412   I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
413   V         0.324   0.436   0.062   0.305   0.463  -0.074   0.310   0.469  -0.140
414   N        -1.398  -1.409  -1.218  -1.489  -1.478  -1.200  -1.424  -1.393  -1.151
415   M         1.011   1.039   1.091   1.192   1.228   1.296   1.069   1.106   1.184
416   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
417   K        -0.015   0.166   0.017  -0.101   0.175  -0.065  -0.232   0.063  -0.222
418   E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
419   S        -0.253  -0.199  -0.068  -0.617  -0.537  -0.303  -0.666  -0.575  -0.377
420   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
421   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
422   T        -0.947  -0.908  -1.149  -0.723  -0.700  -1.069  -0.882  -0.846  -1.079
423   K        -0.631  -0.660  -0.693  -0.606  -0.623  -0.728  -0.774  -0.784  -0.832
424   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
425   Y        -0.631  -0.672  -0.686  -0.555  -0.606  -0.668  -0.774  -0.797  -0.821
426   F         0.324   0.208   0.041   0.469   0.310   0.012   0.310   0.130  -0.178
427   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
428   S         1.011   1.039   1.091   1.017   1.056   1.141   1.069   1.106   1.184
429   A        -0.196  -0.049  -0.021  -0.307  -0.023  -0.037  -0.557  -0.302  -0.289
430   A         1.011   1.039   1.091   0.895   0.932   1.033   1.069   1.106   1.184
431   P         1.011   1.039   1.091   1.118   1.153   1.230   1.069   1.106   1.184
432   A        -0.766  -0.756  -0.696  -0.860  -0.775  -0.681  -0.991  -0.926  -0.835
433   I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
434   R        -0.331  -0.600  -0.677  -0.216  -0.600  -0.727  -0.340  -0.699  -0.807
435   Y        -0.963  -0.916  -0.746  -0.999  -0.920  -0.665  -1.208  -1.128  -0.899
436   N        -0.015  -0.141  -0.062  -0.033  -0.249  -0.138  -0.232  -0.468  -0.365
437   H         1.011   1.039   1.091   1.210   1.242   1.312   1.069   1.106   1.184
438   I        -0.331  -0.413  -0.654  -0.259  -0.382  -0.786  -0.340  -0.450  -0.776
439   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
440   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
441   I         1.011   1.039   1.091   0.977   1.015   1.105   1.069   1.106   1.184
442   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
443   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
444   T        -0.015   0.166   0.017  -0.167   0.096  -0.114  -0.232   0.063  -0.222
445   D         0.324   0.155   0.038   0.376   0.151  -0.047   0.310   0.046  -0.182
446   T        -0.331  -0.600  -0.677  -0.042  -0.410  -0.537  -0.340  -0.699  -0.807
447   K         0.324   0.155   0.038   0.482   0.267   0.070   0.310   0.046  -0.182
448   N        -1.714  -1.724  -1.583  -1.749  -1.771  -1.519  -1.533  -1.501  -1.303
449   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
450   I        -0.196  -0.102  -0.051  -0.499  -0.326  -0.271  -0.557  -0.395  -0.346
451   A        -0.015   0.119   0.005  -0.243  -0.029  -0.234  -0.232  -0.014  -0.243
452   Y        -0.766  -0.800  -0.703  -0.758  -0.755  -0.614  -0.991  -0.982  -0.846
453   N        -1.201  -1.337  -1.204  -1.220  -1.428  -1.263  -1.208  -1.316  -1.137
454   R        -0.253  -0.184  -0.064  -0.514  -0.381  -0.195  -0.666  -0.547  -0.369
455   T        -1.201  -0.955  -1.163  -1.106  -0.753  -1.072  -1.208  -0.916  -1.097
456   D        -0.331  -0.374  -0.645  -0.228  -0.305  -0.718  -0.340  -0.417  -0.764
457   E        -1.714  -1.748  -1.588  -1.663  -1.719  -1.459  -1.533  -1.525  -1.307
458   E        -0.015  -0.080  -0.053  -0.120  -0.241  -0.230  -0.232  -0.357  -0.349
459   V        -0.196  -0.137  -0.058  -0.499  -0.397  -0.285  -0.557  -0.460  -0.358
460   A        -0.331  -0.204  -0.627  -0.291  -0.132  -0.692  -0.340  -0.169  -0.740
461   E        -0.947  -0.937  -1.150  -0.730  -0.738  -0.991  -0.882  -0.877  -1.079
462   V        -1.714  -1.655  -1.566  -1.749  -1.622  -1.469  -1.533  -1.441  -1.289
463   I         0.324   0.436   0.062   0.358   0.501  -0.041   0.310   0.469  -0.140
464   G        -0.331  -0.600  -0.677  -0.313  -0.683  -0.811  -0.340  -0.699  -0.807
465   C        -0.196  -0.049  -0.021  -0.416  -0.193  -0.130  -0.557  -0.302  -0.289
466   E         0.324   0.469   0.066   0.372   0.559  -0.009   0.310   0.516  -0.134
467   R        -1.833  -1.738  -1.585  -1.915  -1.779  -1.549  -1.641  -1.514  -1.305
468   V         1.011   1.039   1.091   0.918   0.973   1.054   1.069   1.106   1.184
469   I        -0.015   0.081  -0.021  -0.098   0.047  -0.126  -0.232  -0.076  -0.290
470   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
471   Q         1.011   1.039   1.091   1.129   1.162   1.240   1.069   1.106   1.184
472   S        -0.963  -0.907  -0.742  -1.163  -1.068  -0.805  -1.208  -1.117  -0.894
473   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
474   E        -1.201  -1.169  -1.180  -1.194  -1.165  -1.182  -1.208  -1.145  -1.113
475   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
476   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
477   I        -0.947  -1.155  -1.189  -0.799  -1.120  -1.164  -0.882  -1.118  -1.121
478   D        -0.631  -0.684  -0.693  -0.715  -0.786  -0.840  -0.774  -0.814  -0.832
479   C        -0.631  -0.776  -0.717  -0.515  -0.791  -0.746  -0.774  -0.956  -0.864
480   C         1.011   1.039   1.091   1.206   1.245   1.308   1.069   1.106   1.184
481   K        -1.201  -1.279  -1.198  -1.147  -1.266  -1.167  -1.208  -1.269  -1.133
482   T        -1.517  -1.474  -1.562  -1.199  -1.181  -1.311  -1.316  -1.262  -1.285
483   D        -1.714  -1.517  -1.569  -1.731  -1.513  -1.495  -1.533  -1.342  -1.292
484   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
485   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
486   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
487   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
488   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
489   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
490   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
491   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
492   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
493   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
494   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
495   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
496   K        -2.149  -2.034  -1.890  -2.029  -1.865  -1.693  -1.750  -1.616  -1.411
497   I         0.324   0.208   0.041   0.358   0.199  -0.080   0.310   0.130  -0.178
498   T        -1.398  -1.198  -1.191  -1.347  -1.047  -1.050  -1.424  -1.182  -1.125
499   K        -1.714  -1.765  -1.587  -1.676  -1.757  -1.520  -1.533  -1.534  -1.306
500   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
501   E         1.011   1.039   1.091   0.989   1.036   1.116   1.069   1.106   1.184
502   D         0.324   0.469   0.066   0.306   0.504  -0.065   0.310   0.516  -0.134
503   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
504   V         0.324   0.208   0.041   0.299   0.157  -0.129   0.310   0.130  -0.178
505   F         1.011   1.039   1.091   1.088   1.127   1.204   1.069   1.106   1.184
506   T        -0.331  -0.459  -0.658  -0.055  -0.229  -0.539  -0.340  -0.518  -0.783
507   G         1.011   1.039   1.091   0.890   0.938   1.029   1.069   1.106   1.184
508   N        -1.714  -1.599  -1.564  -1.638  -1.460  -1.395  -1.533  -1.390  -1.287
509   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
510   V        -1.201  -1.317  -1.202  -1.244  -1.364  -1.184  -1.208  -1.293  -1.135
511   T         1.011   1.039   1.091   1.118   1.152   1.230   1.069   1.106   1.184
512   G         0.324   0.155   0.038   0.278   0.056  -0.137   0.310   0.046  -0.182
513   V        -0.331  -0.600  -0.677  -0.315  -0.706  -0.866  -0.340  -0.699  -0.807
514   E        -0.331  -0.600  -0.677  -0.199  -0.569  -0.703  -0.340  -0.699  -0.807
515   D        -0.331  -0.600  -0.677  -0.218  -0.596  -0.737  -0.340  -0.699  -0.807
516   G        -1.201  -1.179  -1.186  -1.300  -1.245  -1.252  -1.208  -1.148  -1.119
517   Y         1.011   1.039   1.091   1.097   1.138   1.211   1.069   1.106   1.184
518   I        -0.331  -0.374  -0.645  -0.267  -0.336  -0.721  -0.340  -0.417  -0.764
519   Q        -2.030  -2.011  -1.894  -1.842  -1.879  -1.744  -1.641  -1.599  -1.413
520   E        -0.631  -0.696  -0.716  -0.586  -0.689  -0.672  -0.774  -0.887  -0.863
521   L         1.011   1.039   1.091   0.933   0.977   1.067   1.069   1.106   1.184
522   E         0.324   0.155   0.038   0.385   0.167  -0.035   0.310   0.046  -0.182
523   E        -1.398  -1.395  -1.214  -1.460  -1.437  -1.173  -1.424  -1.381  -1.148
524   K        -2.030  -1.961  -1.889  -1.891  -1.798  -1.705  -1.641  -1.562  -1.410
525   R         1.011   1.039   1.091   0.979   1.020   1.108   1.069   1.106   1.184
526   E        -1.201  -1.218  -1.196  -1.374  -1.445  -1.357  -1.208  -1.224  -1.131
527   S        -2.030  -1.961  -1.889  -1.722  -1.684  -1.575  -1.641  -1.562  -1.410
528   I        -0.331  -0.374  -0.645  -0.169  -0.231  -0.650  -0.340  -0.417  -0.764
529   A        -1.714  -1.724  -1.583  -1.677  -1.688  -1.512  -1.533  -1.501  -1.303
530   N        -1.517  -1.375  -1.548  -1.383  -1.197  -1.460  -1.316  -1.169  -1.272
531   N        -1.816  -1.610  -1.582  -1.826  -1.555  -1.429  -1.621  -1.399  -1.302
532   -        -1.419  -1.335  -1.209  -1.526  -1.429  -1.212  -1.429  -1.318  -1.141
533   -        -1.419  -1.408  -1.226  -1.442  -1.452  -1.191  -1.429  -1.392  -1.159
534   -        -1.419  -1.335  -1.209  -1.398  -1.292  -1.135  -1.429  -1.318  -1.141
535   -        -1.924  -1.810  -1.605  -2.091  -1.892  -1.607  -1.706  -1.569  -1.320
536   -        -1.419  -1.381  -1.217  -1.566  -1.533  -1.241  -1.429  -1.366  -1.150
537   -        -1.924  -1.810  -1.605  -1.956  -1.792  -1.487  -1.706  -1.569  -1.320
538   -        -1.419  -1.408  -1.226  -1.662  -1.628  -1.355  -1.429  -1.392  -1.159
539   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
540   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
541   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
542   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
543   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
544   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
545   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
546   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
547   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
548   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
549   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
550   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
551   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
552   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
553   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
554   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
555   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
556   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
557   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
558   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
559   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
560   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
561   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
562   S        -2.149  -2.037  -1.893  -2.059  -1.877  -1.696  -1.750  -1.620  -1.413
563   S        -1.398  -1.152  -1.189  -1.636  -1.216  -1.286  -1.424  -1.131  -1.122
564   D        -0.947  -1.109  -1.177  -0.810  -1.061  -1.176  -0.882  -1.072  -1.109
565   M        -1.714  -1.637  -1.577  -1.691  -1.581  -1.458  -1.533  -1.441  -1.299
566   K        -0.015  -0.141  -0.062  -0.037  -0.280  -0.184  -0.232  -0.468  -0.365
567   A        -0.331  -0.365  -0.644  -0.290  -0.361  -0.715  -0.340  -0.406  -0.763
568   E        -1.201  -1.336  -1.203  -1.212  -1.395  -1.203  -1.208  -1.314  -1.137
569   V        -1.201  -1.304  -1.194  -1.256  -1.367  -1.207  -1.208  -1.278  -1.127
570   D         1.011   1.039   1.091   0.983   1.028   1.111   1.069   1.106   1.184
571   I         0.324   0.480   0.067   0.355   0.553  -0.038   0.310   0.530  -0.132
572   G        -0.253  -0.178  -0.060  -0.621  -0.470  -0.277  -0.666  -0.537  -0.362
573   L        -0.253  -0.201  -0.070  -0.619  -0.534  -0.304  -0.666  -0.580  -0.381
574   Y        -0.015  -0.141  -0.062   0.056  -0.158  -0.042  -0.232  -0.468  -0.365
575   N         1.011   1.039   1.091   1.035   1.086   1.156   1.069   1.106   1.184
576   C        -2.465  -2.377  -2.166  -2.204  -2.110  -1.848  -1.858  -1.749  -1.497
577   A        -0.766  -0.812  -0.712  -1.045  -1.075  -0.867  -0.991  -1.012  -0.858
578   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
579   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
580   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
581   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
582   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
583   D         0.324   0.155   0.038   0.378   0.159  -0.040   0.310   0.046  -0.182
584   Y         0.263   0.075   0.001   0.419   0.151   0.004   0.219  -0.086  -0.250
585   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
586   -        -1.835  -1.673  -1.583  -1.824  -1.598  -1.459  -1.629  -1.448  -1.302
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P04046
Output conservation file - output/P04046
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
