1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    M         0.827   0.834   0.884   1.157   1.162   1.194   0.864   0.873   0.945
11    S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
12    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
13    S         0.012  -0.014  -0.361   0.232   0.205  -0.304   0.021  -0.016  -0.569
14    S        -1.281  -1.303  -1.191  -1.181  -1.179  -1.033  -1.422  -1.423  -1.228
15    K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
16    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
17    S        -1.121  -1.148  -1.173  -0.983  -1.016  -1.136  -1.182  -1.199  -1.206
18    V        -0.605  -0.643  -0.442  -0.869  -0.929  -0.595  -0.941  -1.014  -0.709
19    Q        -1.798  -1.872  -1.736  -1.707  -1.802  -1.569  -1.663  -1.718  -1.506
20    D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
21    L        -0.390  -0.496  -0.428  -0.650  -0.844  -0.750  -0.580  -0.761  -0.683
22    D         0.012   0.094  -0.353   0.157   0.252  -0.390   0.021   0.132  -0.557
23    L        -0.605  -0.551  -0.431  -1.042  -0.947  -0.757  -0.941  -0.854  -0.690
24    K        -1.496  -1.364  -1.714  -1.425  -1.252  -1.726  -1.302  -1.156  -1.484
25    D        -1.121  -1.049  -1.160  -1.162  -1.046  -1.185  -1.182  -1.074  -1.190
26    K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
27    R         0.012  -0.081  -0.365   0.408   0.295  -0.181   0.021  -0.111  -0.576
28    V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
29    F        -0.390  -0.496  -0.428  -0.345  -0.553  -0.542  -0.580  -0.761  -0.683
30    I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
31    R         0.827   0.834   0.884   1.083   1.093   1.133   0.864   0.873   0.945
32    V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
33    D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
34    F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
35    N         0.827   0.834   0.884   0.973   0.985   1.039   0.864   0.873   0.945
36    V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
37    P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
38    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
39    D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
40    G         0.012  -0.104  -0.365  -0.014  -0.171  -0.602   0.021  -0.143  -0.576
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    K        -0.765  -0.878  -1.155  -0.734  -0.880  -1.234  -0.700  -0.844  -1.183
43    K        -1.281  -1.323  -1.192  -1.399  -1.434  -1.163  -1.422  -1.452  -1.231
44    I         0.012  -0.104  -0.365   0.226   0.073  -0.405   0.021  -0.143  -0.576
45    T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
46    S        -0.605  -0.534  -0.421  -0.640  -0.514  -0.397  -0.941  -0.825  -0.673
47    N         0.012  -0.104  -0.365   0.303   0.165  -0.251   0.021  -0.143  -0.576
48    Q         0.012  -0.081  -0.365   0.416   0.295  -0.269   0.021  -0.111  -0.576
49    R         0.827   0.834   0.884   1.083   1.093   1.133   0.864   0.873   0.945
50    I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
51    V         0.012  -0.104  -0.365  -0.029  -0.182  -0.613   0.021  -0.143  -0.576
52    A        -0.390  -0.496  -0.428  -0.639  -0.834  -0.738  -0.580  -0.761  -0.683
53    A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
54    L         0.012  -0.104  -0.365  -0.028  -0.169  -0.519   0.021  -0.143  -0.576
55    P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
56    T         0.012  -0.014  -0.361   0.296   0.264  -0.279   0.021  -0.016  -0.569
57    I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
58    K         0.012   0.039  -0.358  -0.031   0.003  -0.449   0.021   0.057  -0.566
59    Y         0.827   0.834   0.884   1.153   1.162   1.192   0.864   0.873   0.945
60    V        -0.605  -0.643  -0.442  -1.024  -1.118  -0.772  -0.941  -1.014  -0.709
61    L        -0.765  -0.719  -1.144  -0.708  -0.653  -1.214  -0.700  -0.646  -1.170
62    E        -0.390  -0.465  -0.423  -0.405  -0.534  -0.516  -0.580  -0.708  -0.676
63    H        -1.798  -1.777  -1.739  -1.298  -1.289  -1.348  -1.663  -1.656  -1.509
64    H        -2.406  -2.365  -2.179  -2.290  -2.259  -1.846  -2.024  -1.996  -1.690
65    P        -0.390  -0.465  -0.423  -0.315  -0.462  -0.506  -0.580  -0.708  -0.676
66    R        -0.390  -0.276  -0.379  -0.549  -0.391  -0.499  -0.580  -0.402  -0.601
67    Y        -0.605  -0.515  -0.424  -0.780  -0.661  -0.485  -0.941  -0.792  -0.677
68    V        -0.390  -0.327  -0.412  -0.527  -0.435  -0.561  -0.580  -0.483  -0.657
69    V        -0.605  -0.613  -0.439  -0.869  -0.886  -0.595  -0.941  -0.962  -0.704
70    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
71    A        -0.390  -0.496  -0.428  -0.486  -0.635  -0.485  -0.580  -0.761  -0.683
72    S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
73    H         0.827   0.834   0.884   1.145   1.153   1.184   0.864   0.873   0.945
74    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
75    G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
76    R         0.827   0.834   0.884   1.083   1.093   1.133   0.864   0.873   0.945
77    P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
78    N         0.012  -0.104  -0.365   0.281   0.137  -0.315   0.021  -0.143  -0.576
79    G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
80    E        -1.496  -1.689  -1.736  -1.218  -1.512  -1.660  -1.302  -1.515  -1.506
81    R        -1.496  -1.528  -1.718  -1.006  -1.052  -1.515  -1.302  -1.342  -1.489
82    N        -0.605  -0.613  -0.439  -0.750  -0.783  -0.555  -0.941  -0.962  -0.704
83    E        -1.890  -1.986  -1.748  -1.847  -1.972  -1.642  -1.783  -1.855  -1.518
84    K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
85    Y         0.012   0.070  -0.358   0.477   0.545  -0.117   0.021   0.100  -0.565
86    S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
87    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
88    A        -0.605  -0.643  -0.442  -1.078  -1.172  -0.820  -0.941  -1.014  -0.709
89    P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
90    V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
91    A        -0.765  -0.898  -1.157  -0.694  -0.873  -1.208  -0.700  -0.870  -1.187
92    K        -3.297  -3.186  -2.834  -3.054  -2.895  -2.421  -2.385  -2.305  -1.887
93    E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
94    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
95    Q        -1.515  -1.449  -1.199  -1.497  -1.419  -1.055  -1.663  -1.589  -1.239
96    S        -1.121  -1.004  -1.166  -1.202  -1.031  -1.180  -1.182  -1.021  -1.197
97    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
98    L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
99    G         0.012   0.039  -0.358   0.057   0.086  -0.383   0.021   0.057  -0.566
100   K         0.012   0.093  -0.355  -0.031   0.062  -0.444   0.021   0.131  -0.559
101   D        -1.281  -1.193  -1.183  -1.355  -1.250  -1.207  -1.422  -1.335  -1.221
102   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
103   T        -0.765  -0.802  -1.150  -0.411  -0.477  -1.070  -0.700  -0.752  -1.177
104   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
105   L         0.012  -0.104  -0.365  -0.070  -0.224  -0.645   0.021  -0.143  -0.576
106   N        -1.890  -1.915  -1.745  -1.642  -1.673  -1.392  -1.783  -1.793  -1.515
107   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
108   C         0.827   0.834   0.884   1.197   1.202   1.229   0.864   0.873   0.945
109   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
110   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
111   P        -1.496  -1.363  -1.708  -1.032  -0.864  -1.443  -1.302  -1.155  -1.478
112   E        -0.765  -0.740  -1.146  -0.543  -0.517  -1.156  -0.700  -0.672  -1.173
113   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
114   E        -1.121  -1.001  -1.168  -1.001  -0.839  -1.092  -1.182  -1.032  -1.201
115   A        -2.406  -2.302  -2.177  -2.422  -2.287  -2.062  -2.024  -1.944  -1.688
116   A        -0.765  -0.898  -1.157  -0.702  -0.874  -1.228  -0.700  -0.870  -1.187
117   V         0.012  -0.081  -0.365   0.052  -0.051  -0.375   0.021  -0.111  -0.576
118   K        -1.890  -1.845  -1.740  -1.898  -1.829  -1.643  -1.783  -1.739  -1.511
119   A        -2.547  -2.520  -2.186  -2.671  -2.638  -2.142  -2.144  -2.112  -1.695
120   S        -1.121  -0.977  -1.159  -1.240  -1.031  -1.304  -1.182  -0.991  -1.189
121   A        -1.798  -1.765  -1.728  -1.959  -1.889  -1.805  -1.663  -1.614  -1.498
122   P        -1.798  -1.872  -1.736  -1.597  -1.699  -1.549  -1.663  -1.718  -1.506
123   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
124   S        -0.390  -0.276  -0.379  -0.386  -0.214  -0.410  -0.580  -0.402  -0.601
125   V         0.012   0.093  -0.355   0.013   0.108  -0.473   0.021   0.131  -0.559
126   I        -0.605  -0.551  -0.431  -0.633  -0.546  -0.402  -0.941  -0.854  -0.690
127   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
128   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
129   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
130   N         0.827   0.834   0.884   0.973   0.985   1.039   0.864   0.873   0.945
131   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
132   R         0.827   0.834   0.884   1.083   1.093   1.133   0.864   0.873   0.945
133   Y        -0.605  -0.515  -0.424  -0.511  -0.376  -0.274  -0.941  -0.792  -0.677
134   H         0.827   0.834   0.884   1.145   1.153   1.184   0.864   0.873   0.945
135   I         0.012  -0.014  -0.361   0.270   0.240  -0.269   0.021  -0.016  -0.569
136   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
137   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
138   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
139   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
140   S         0.012  -0.104  -0.365   0.181   0.029  -0.462   0.021  -0.143  -0.576
141   R        -2.781  -2.826  -2.539  -2.139  -2.264  -1.952  -2.144  -2.178  -1.808
142   K         0.012  -0.104  -0.365  -0.055  -0.192  -0.527   0.021  -0.143  -0.576
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   V        -1.423  -1.413  -1.208  -1.831  -1.829  -1.530  -1.542  -1.535  -1.248
145   D         0.012  -0.104  -0.365   0.157   0.009  -0.409   0.021  -0.143  -0.576
146   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
147   Q        -2.031  -1.960  -1.748  -1.983  -1.909  -1.570  -1.903  -1.834  -1.518
148   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
149   V         0.012  -0.014  -0.361   0.013  -0.017  -0.482   0.021  -0.016  -0.569
150   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
151   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
152   S        -0.605  -0.523  -0.427  -0.750  -0.613  -0.493  -0.941  -0.806  -0.682
153   K        -2.031  -1.982  -1.752  -2.263  -2.207  -1.840  -1.903  -1.856  -1.522
154   E        -1.281  -1.345  -1.192  -1.451  -1.552  -1.285  -1.422  -1.485  -1.231
155   D        -1.515  -1.515  -1.215  -1.907  -1.937  -1.458  -1.663  -1.660  -1.256
156   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
157   Q        -2.406  -2.233  -2.175  -2.283  -2.026  -1.940  -2.024  -1.864  -1.686
158   K        -1.121  -1.255  -1.193  -1.311  -1.520  -1.424  -1.182  -1.353  -1.232
159   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
160   R         0.827   0.834   0.884   1.083   1.093   1.133   0.864   0.873   0.945
161   H        -1.798  -1.643  -1.727  -1.668  -1.491  -1.493  -1.663  -1.495  -1.497
162   E        -2.031  -2.078  -1.760  -1.818  -1.872  -1.437  -1.903  -1.937  -1.528
163   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
164   S        -1.121  -0.987  -1.175  -0.840  -0.663  -0.918  -1.182  -1.012  -1.209
165   S        -0.765  -0.822  -1.150  -0.486  -0.577  -1.123  -0.700  -0.779  -1.178
166   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
167   A        -0.390  -0.496  -0.428  -0.639  -0.834  -0.738  -0.580  -0.761  -0.683
168   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
169   V         0.012  -0.081  -0.365   0.013  -0.099  -0.489   0.021  -0.111  -0.576
170   Y         0.012  -0.081  -0.365   0.477   0.363  -0.129   0.021  -0.111  -0.576
171   I        -0.673  -0.654  -0.442  -0.959  -0.940  -0.595  -1.061  -1.035  -0.708
172   N         0.827   0.834   0.884   0.973   0.985   1.039   0.864   0.873   0.945
173   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
174   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
175   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
176   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
177   T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
178   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
179   H         0.827   0.834   0.884   1.145   1.153   1.184   0.864   0.873   0.945
180   R         0.827   0.834   0.884   1.083   1.093   1.133   0.864   0.873   0.945
181   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
182   H         0.827   0.834   0.884   1.145   1.153   1.184   0.864   0.873   0.945
183   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
184   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
185   M         0.012   0.039  -0.358   0.476   0.504  -0.128   0.021   0.057  -0.566
186   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
187   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
188   F        -2.031  -2.061  -1.762  -2.019  -2.064  -1.694  -1.903  -1.921  -1.530
189   D        -0.605  -0.568  -0.433  -0.780  -0.720  -0.535  -0.941  -0.883  -0.692
190   L         0.012   0.093  -0.355  -0.065   0.035  -0.611   0.021   0.131  -0.559
191   P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
192   Q        -0.896  -1.005  -1.171  -0.431  -0.610  -0.985  -0.865  -1.011  -1.203
193   R        -0.390  -0.424  -0.423  -0.248  -0.319  -0.467  -0.580  -0.641  -0.675
194   A         0.012  -0.081  -0.365  -0.059  -0.180  -0.625   0.021  -0.111  -0.576
195   A         0.012  -0.081  -0.365  -0.028  -0.140  -0.531   0.021  -0.111  -0.576
196   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
197   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
198   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
199   L        -1.281  -1.254  -1.187  -1.236  -1.157  -1.145  -1.422  -1.372  -1.224
200   E        -2.547  -2.439  -2.184  -2.625  -2.520  -2.072  -2.144  -2.059  -1.694
201   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
202   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
203   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
204   K        -1.890  -1.864  -1.741  -1.684  -1.639  -1.542  -1.783  -1.757  -1.511
205   Y         0.012  -0.014  -0.361   0.477   0.446  -0.122   0.021  -0.016  -0.569
206   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
207   G        -1.121  -1.106  -1.165  -1.280  -1.227  -1.319  -1.182  -1.141  -1.196
208   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
209   A         0.012  -0.104  -0.365  -0.059  -0.211  -0.626   0.021  -0.143  -0.576
210   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
211   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
212   N        -0.765  -0.898  -1.157  -0.344  -0.512  -0.909  -0.700  -0.870  -1.187
213   P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
214   T        -2.406  -2.467  -2.185  -2.127  -2.215  -1.901  -2.024  -2.066  -1.694
215   R         0.827   0.834   0.884   1.083   1.093   1.133   0.864   0.873   0.945
216   P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
217   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
218   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
219   A         0.012  -0.104  -0.365  -0.028  -0.169  -0.531   0.021  -0.143  -0.576
220   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
221   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
222   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
223   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
224   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
225   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
226   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
227   A        -0.673  -0.655  -0.443  -1.011  -0.978  -0.634  -1.061  -1.036  -0.709
228   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
229   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
230   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
231   Q         0.827   0.834   0.884   1.135   1.148   1.176   0.864   0.873   0.945
232   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
233   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
234   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
235   N         0.827   0.834   0.884   0.973   0.985   1.039   0.864   0.873   0.945
236   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
237   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
238   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
239   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
240   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
241   D        -0.605  -0.643  -0.442  -0.713  -0.783  -0.477  -0.941  -1.014  -0.709
242   S        -2.781  -2.826  -2.539  -2.297  -2.372  -2.039  -2.144  -2.178  -1.808
243   I        -0.390  -0.276  -0.379  -0.566  -0.401  -0.542  -0.580  -0.402  -0.601
244   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
245   I        -0.605  -0.595  -0.437  -0.780  -0.773  -0.569  -0.941  -0.930  -0.699
246   G        -0.390  -0.496  -0.428  -0.425  -0.575  -0.430  -0.580  -0.761  -0.683
247   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
248   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
249   M         0.827   0.834   0.884   1.157   1.162   1.194   0.864   0.873   0.945
250   A         0.012   0.070  -0.358  -0.028   0.042  -0.520   0.021   0.100  -0.565
251   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
252   T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
253   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
254   K         0.012  -0.081  -0.365  -0.104  -0.225  -0.674   0.021  -0.111  -0.576
255   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
256   V        -1.121  -1.118  -1.183  -1.131  -1.153  -1.175  -1.182  -1.207  -1.219
257   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
258   E        -1.798  -1.843  -1.743  -1.543  -1.594  -1.450  -1.663  -1.710  -1.513
259   N        -0.765  -0.781  -1.147  -0.461  -0.489  -1.176  -0.700  -0.727  -1.174
260   T        -1.798  -1.707  -1.735  -1.404  -1.269  -1.492  -1.663  -1.558  -1.505
261   E        -1.515  -1.513  -1.215  -1.661  -1.677  -1.257  -1.663  -1.658  -1.257
262   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
263   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
264   D        -0.390  -0.465  -0.423  -0.364  -0.487  -0.451  -0.580  -0.708  -0.676
265   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
266   I        -0.605  -0.534  -0.421  -0.904  -0.796  -0.602  -0.941  -0.825  -0.673
267   F         0.012   0.039  -0.358   0.325   0.356  -0.178   0.021   0.057  -0.566
268   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
269   K        -1.121  -1.004  -1.166  -1.175  -0.974  -1.330  -1.182  -1.021  -1.197
270   A         0.012  -0.014  -0.361  -0.036  -0.067  -0.549   0.021  -0.016  -0.569
271   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
272   A        -0.390  -0.453  -0.421  -0.572  -0.674  -0.617  -0.580  -0.688  -0.672
273   E        -0.605  -0.534  -0.421  -0.985  -0.868  -0.676  -0.941  -0.825  -0.673
274   I        -1.281  -1.250  -1.189  -1.231  -1.190  -1.142  -1.422  -1.386  -1.227
275   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
276   P        -1.281  -1.287  -1.192  -1.255  -1.267  -1.177  -1.422  -1.422  -1.231
277   K        -2.781  -2.826  -2.539  -2.543  -2.630  -2.158  -2.144  -2.178  -1.808
278   L         0.012  -0.081  -0.365   0.005  -0.100  -0.422   0.021  -0.111  -0.576
279   M        -0.605  -0.575  -0.433  -0.749  -0.711  -0.465  -0.941  -0.895  -0.693
280   E        -1.121  -1.233  -1.186  -1.167  -1.354  -1.377  -1.182  -1.314  -1.223
281   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
282   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
283   K         0.012  -0.104  -0.365  -0.075  -0.217  -0.586   0.021  -0.143  -0.576
284   A        -0.390  -0.276  -0.379  -0.695  -0.509  -0.699  -0.580  -0.402  -0.601
285   K        -0.390  -0.276  -0.379  -0.356  -0.164  -0.441  -0.580  -0.402  -0.601
286   G        -0.390  -0.276  -0.379  -0.328  -0.143  -0.403  -0.580  -0.402  -0.601
287   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
288   E        -0.673  -0.653  -0.442  -1.082  -1.059  -0.699  -1.061  -1.032  -0.708
289   V        -1.515  -1.477  -1.215  -1.869  -1.823  -1.381  -1.663  -1.618  -1.257
290   V        -0.765  -0.781  -1.147  -0.646  -0.670  -1.138  -0.700  -0.727  -1.174
291   L         0.012  -0.014  -0.361  -0.023  -0.053  -0.499   0.021  -0.016  -0.569
292   P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
293   V         0.012   0.039  -0.358   0.019   0.052  -0.462   0.021   0.057  -0.566
294   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
295   F         0.012  -0.014  -0.361   0.325   0.296  -0.182   0.021  -0.016  -0.569
296   I        -1.121  -1.136  -1.174  -1.139  -1.140  -1.170  -1.182  -1.180  -1.209
297   I        -0.673  -0.656  -0.443  -0.751  -0.729  -0.416  -1.061  -1.038  -0.709
298   A         0.012   0.039  -0.358  -0.057  -0.024  -0.607   0.021   0.057  -0.566
299   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
300   A        -0.390  -0.276  -0.379  -0.695  -0.509  -0.699  -0.580  -0.402  -0.601
301   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
302   S        -0.673  -0.652  -0.442  -0.871  -0.842  -0.518  -1.061  -1.030  -0.708
303   A        -0.605  -0.534  -0.421  -1.092  -0.961  -0.781  -0.941  -0.825  -0.673
304   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
305   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
306   N        -0.673  -0.656  -0.443  -0.987  -0.964  -0.617  -1.061  -1.038  -0.709
307   T        -0.390  -0.453  -0.421  -0.326  -0.449  -0.499  -0.580  -0.688  -0.672
308   K        -1.515  -1.448  -1.211  -1.899  -1.794  -1.399  -1.663  -1.582  -1.251
309   T        -2.922  -2.907  -2.533  -2.380  -2.346  -1.897  -2.264  -2.244  -1.805
310   V        -0.605  -0.534  -0.421  -1.037  -0.909  -0.734  -0.941  -0.825  -0.673
311   T         0.012   0.094  -0.353   0.296   0.391  -0.266   0.021   0.132  -0.557
312   D        -0.765  -0.802  -1.150  -0.557  -0.621  -1.200  -0.700  -0.752  -1.177
313   K        -1.798  -1.804  -1.741  -1.973  -1.981  -1.856  -1.663  -1.665  -1.511
314   E         0.012  -0.104  -0.365   0.157   0.012  -0.409   0.021  -0.143  -0.576
315   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
316   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
317   P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
318   A        -1.121  -1.004  -1.166  -1.112  -0.921  -1.208  -1.182  -1.021  -1.197
319   G        -0.390  -0.308  -0.400  -0.501  -0.385  -0.516  -0.580  -0.452  -0.636
320   W         0.827   0.834   0.884   1.204   1.211   1.234   0.864   0.873   0.945
321   Q        -0.673  -0.652  -0.442  -0.489  -0.459  -0.194  -1.061  -1.030  -0.708
322   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
323   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
324   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
325   N        -1.281  -1.191  -1.186  -1.023  -0.876  -0.978  -1.422  -1.308  -1.223
326   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
327   P         0.012  -0.104  -0.365   0.311   0.163  -0.292   0.021  -0.143  -0.576
328   E        -0.673  -0.656  -0.443  -1.082  -1.059  -0.698  -1.061  -1.038  -0.709
329   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
330   R        -2.406  -2.438  -2.184  -2.038  -2.116  -1.802  -2.024  -2.047  -1.693
331   K        -1.281  -1.323  -1.192  -1.578  -1.631  -1.417  -1.422  -1.452  -1.231
332   L        -1.496  -1.578  -1.722  -1.480  -1.611  -1.897  -1.302  -1.394  -1.492
333   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
334   A        -1.121  -1.192  -1.183  -1.093  -1.176  -1.102  -1.182  -1.257  -1.219
335   A        -2.031  -2.070  -1.760  -2.138  -2.167  -1.702  -1.903  -1.930  -1.529
336   T        -1.423  -1.467  -1.216  -1.534  -1.652  -1.332  -1.542  -1.600  -1.257
337   V        -0.673  -0.644  -0.439  -0.959  -0.893  -0.577  -1.061  -1.017  -0.703
338   A        -1.496  -1.689  -1.736  -1.361  -1.620  -1.678  -1.302  -1.515  -1.506
339   K        -1.281  -1.290  -1.185  -1.458  -1.413  -1.248  -1.422  -1.404  -1.222
340   A        -0.605  -0.643  -0.442  -0.919  -0.978  -0.639  -0.941  -1.014  -0.709
341   K         0.012  -0.104  -0.365  -0.031  -0.160  -0.457   0.021  -0.143  -0.576
342   T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
343   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
344   V        -0.390  -0.465  -0.423  -0.623  -0.763  -0.734  -0.580  -0.708  -0.676
345   W         0.827   0.834   0.884   1.204   1.211   1.234   0.864   0.873   0.945
346   N         0.827   0.834   0.884   0.973   0.985   1.039   0.864   0.873   0.945
347   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
348   P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
349   P        -0.390  -0.496  -0.428  -0.315  -0.524  -0.518  -0.580  -0.761  -0.683
350   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
351   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
352   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
353   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
354   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
355   E        -1.281  -1.201  -1.186  -1.383  -1.248  -1.260  -1.422  -1.310  -1.223
356   K        -1.281  -1.263  -1.189  -1.421  -1.392  -1.194  -1.422  -1.406  -1.228
357   F         0.827   0.834   0.884   0.973   0.983   1.039   0.864   0.873   0.945
358   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
359   A        -1.496  -1.272  -1.706  -1.427  -1.136  -1.719  -1.302  -1.054  -1.477
360   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
361   T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
362   K         0.012   0.039  -0.358  -0.075  -0.039  -0.576   0.021   0.057  -0.566
363   A        -0.605  -0.588  -0.435  -0.919  -0.895  -0.635  -0.941  -0.919  -0.696
364   L        -1.798  -1.899  -1.743  -1.703  -1.829  -1.578  -1.663  -1.761  -1.513
365   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
366   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
367   E        -0.390  -0.276  -0.379  -0.592  -0.420  -0.580  -0.580  -0.402  -0.601
368   V        -1.515  -1.448  -1.211  -1.611  -1.451  -1.180  -1.663  -1.582  -1.251
369   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
370   K         0.012   0.039  -0.358  -0.104  -0.067  -0.660   0.021   0.057  -0.566
371   S        -1.121  -1.255  -1.193  -1.043  -1.266  -1.204  -1.182  -1.353  -1.232
372   S        -1.890  -1.938  -1.749  -1.885  -1.936  -1.626  -1.783  -1.814  -1.519
373   A        -2.173  -2.039  -2.161  -1.782  -1.605  -1.819  -1.783  -1.654  -1.675
374   A        -2.031  -2.042  -1.753  -2.076  -2.086  -1.653  -1.903  -1.898  -1.523
375   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
376   N        -0.765  -0.898  -1.157  -0.393  -0.563  -1.029  -0.700  -0.870  -1.187
377   T        -0.765  -0.781  -1.147  -0.405  -0.443  -1.050  -0.700  -0.727  -1.174
378   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
379   I         0.827   0.834   0.884   0.940   0.949   1.011   0.864   0.873   0.945
380   I         0.012  -0.081  -0.365   0.226   0.104  -0.404   0.021  -0.111  -0.576
381   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
382   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
383   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
384   D         0.827   0.834   0.884   0.848   0.856   0.934   0.864   0.873   0.945
385   T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
386   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
387   T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
388   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
389   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
390   K         0.012  -0.104  -0.365  -0.104  -0.254  -0.672   0.021  -0.143  -0.576
391   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
392   Y         0.827   0.834   0.884   1.153   1.162   1.192   0.864   0.873   0.945
393   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
394   V        -0.765  -0.878  -1.155  -0.756  -0.919  -1.423  -0.700  -0.844  -1.183
395   T        -1.515  -1.437  -1.203  -1.710  -1.592  -1.240  -1.663  -1.572  -1.243
396   D         0.012   0.093  -0.355   0.157   0.251  -0.392   0.021   0.131  -0.559
397   K         0.012  -0.081  -0.365  -0.104  -0.224  -0.671   0.021  -0.111  -0.576
398   I        -0.605  -0.534  -0.421  -0.904  -0.796  -0.602  -0.941  -0.825  -0.673
399   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
400   H         0.827   0.834   0.884   1.145   1.153   1.184   0.864   0.873   0.945
401   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
402   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
403   T         0.827   0.834   0.884   0.980   0.988   1.045   0.864   0.873   0.945
404   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
405   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
406   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
407   A         0.827   0.834   0.884   0.656   0.666   0.771   0.864   0.873   0.945
408   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
409   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
410   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
411   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
412   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
413   E         0.827   0.834   0.884   0.848   0.859   0.934   0.864   0.873   0.945
414   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
415   K         0.827   0.834   0.884   0.617   0.629   0.738   0.864   0.873   0.945
416   E        -1.798  -1.819  -1.746  -1.721  -1.812  -1.670  -1.663  -1.704  -1.516
417   L         0.827   0.834   0.884   0.650   0.660   0.767   0.864   0.873   0.945
418   P         0.827   0.834   0.884   1.003   1.011   1.064   0.864   0.873   0.945
419   G         0.827   0.834   0.884   0.705   0.712   0.813   0.864   0.873   0.945
420   V         0.827   0.834   0.884   0.691   0.702   0.801   0.864   0.873   0.945
421   A        -1.281  -1.227  -1.188  -1.569  -1.481  -1.336  -1.422  -1.351  -1.226
422   F        -0.605  -0.534  -0.421  -0.881  -0.774  -0.581  -0.941  -0.825  -0.673
423   L         0.012   0.070  -0.358  -0.028   0.040  -0.509   0.021   0.100  -0.565
424   S         0.827   0.834   0.884   0.905   0.918   0.982   0.864   0.873   0.945
425   E        -1.798  -1.784  -1.737  -1.595  -1.571  -1.531  -1.663  -1.639  -1.508
426   K         0.012  -0.104  -0.365  -0.039  -0.171  -0.480   0.021  -0.143  -0.576
427   K        -1.508  -1.485  -1.215  -1.612  -1.571  -1.154  -1.650  -1.624  -1.256
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P00560
Output conservation file - output/P00560
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
