1     M         1.006   1.016   1.082   1.232   1.245   1.327   1.066   1.081   1.174
2     D         0.333   0.207   0.051   0.421   0.259  -0.013   0.319   0.123  -0.171
3     L        -0.308  -0.385  -0.630  -0.367  -0.474  -0.785  -0.321  -0.433  -0.762
4     V         0.333   0.207   0.051   0.291   0.125  -0.096   0.319   0.123  -0.171
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     N         0.333   0.207   0.051   0.559   0.387   0.086   0.319   0.123  -0.171
7     H        -0.308  -0.355  -0.626   0.123   0.038  -0.406  -0.321  -0.396  -0.756
8     L         0.333   0.207   0.051   0.213   0.061  -0.145   0.319   0.123  -0.171
9     T        -1.662  -1.701  -1.550  -1.427  -1.502  -1.308  -1.495  -1.514  -1.291
10    D         0.333   0.207   0.051   0.457   0.309   0.084   0.319   0.123  -0.171
11    R         0.333   0.421   0.074   0.504   0.612   0.098   0.319   0.444  -0.131
12    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
13    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
14    F         1.006   1.016   1.082   1.188   1.205   1.289   1.066   1.081   1.174
15    A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
16    I         0.002   0.100   0.010  -0.217  -0.063  -0.221  -0.215  -0.052  -0.245
17    P         1.006   1.016   1.082   1.140   1.156   1.246   1.066   1.081   1.174
18    K         1.006   1.016   1.082   0.990   1.016   1.111   1.066   1.081   1.174
19    K         1.006   1.016   1.082   0.990   1.016   1.111   1.066   1.081   1.174
20    G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
21    R         1.006   1.016   1.082   1.103   1.115   1.212   1.066   1.081   1.174
22    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
23    Y         0.333   0.207   0.051   0.616   0.432   0.100   0.319   0.123  -0.171
24    S        -0.308  -0.360  -0.623  -0.146  -0.213  -0.607  -0.321  -0.402  -0.752
25    K        -0.308  -0.520  -0.648  -0.211  -0.509  -0.764  -0.321  -0.610  -0.786
26    S        -1.160  -0.999  -1.143  -0.961  -0.704  -0.992  -1.175  -0.980  -1.092
27    V        -1.160  -1.167  -1.157  -1.226  -1.262  -1.238  -1.175  -1.169  -1.106
28    S        -1.236  -1.121  -1.156  -1.169  -0.983  -1.018  -1.282  -1.154  -1.108
29    I        -0.601  -0.610  -0.661  -0.888  -0.883  -0.980  -0.748  -0.739  -0.805
30    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
31    N        -1.160  -1.170  -1.152  -1.107  -1.110  -1.102  -1.175  -1.172  -1.102
32    G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
33    A        -0.734  -0.666  -0.679  -0.975  -0.886  -0.884  -0.962  -0.887  -0.836
34    D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
35    I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
36    T        -0.734  -0.664  -0.685  -0.742  -0.654  -0.661  -0.962  -0.882  -0.842
37    F         1.006   1.016   1.082   1.188   1.205   1.289   1.066   1.081   1.174
38    H        -0.734  -0.638  -0.678  -0.604  -0.477  -0.503  -0.962  -0.826  -0.831
39    R         1.006   1.016   1.082   1.103   1.115   1.212   1.066   1.081   1.174
40    S        -0.911  -1.037  -1.147  -0.682  -0.866  -0.985  -0.855  -1.011  -1.094
41    Q        -0.911  -0.872  -1.122  -0.557  -0.510  -0.912  -0.855  -0.816  -1.067
42    R         1.006   1.016   1.082   1.103   1.115   1.212   1.066   1.081   1.174
43    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
44    D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
45    I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
46    A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
47    L         0.002   0.102  -0.005  -0.302  -0.136  -0.321  -0.215  -0.048  -0.274
48    S        -0.601  -0.652  -0.688  -0.652  -0.790  -0.781  -0.748  -0.848  -0.844
49    T        -0.308  -0.520  -0.648  -0.077  -0.372  -0.594  -0.321  -0.610  -0.786
50    S        -0.308  -0.198  -0.608  -0.011   0.135  -0.496  -0.321  -0.176  -0.731
51    L         0.333   0.421   0.074   0.227   0.336  -0.075   0.319   0.444  -0.131
52    P         1.006   1.016   1.082   1.140   1.156   1.246   1.066   1.081   1.174
53    V        -0.601  -0.452  -0.644  -0.771  -0.525  -0.885  -0.748  -0.541  -0.782
54    A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
55    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
56    V        -0.232  -0.195  -0.057  -0.645  -0.588  -0.347  -0.641  -0.581  -0.370
57    F         1.006   1.016   1.082   1.188   1.205   1.289   1.066   1.081   1.174
58    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
59    P         1.006   1.016   1.082   1.140   1.156   1.246   1.066   1.081   1.174
60    A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
61    A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
62    D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
63    I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
64    P         1.006   1.016   1.082   1.140   1.156   1.246   1.066   1.081   1.174
65    T        -1.662  -1.539  -1.536  -1.516  -1.361  -1.355  -1.495  -1.379  -1.281
66    F         1.006   1.016   1.082   1.188   1.205   1.289   1.066   1.081   1.174
67    V         1.006   1.016   1.082   0.876   0.888   1.009   1.066   1.081   1.174
68    G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
69    E         0.333   0.229   0.055   0.428   0.298   0.025   0.319   0.158  -0.164
70    G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
71    K        -0.850  -0.746  -0.691  -0.877  -0.705  -0.660  -1.068  -0.923  -0.844
72    C        -0.175  -0.194  -0.062  -0.259  -0.342  -0.160  -0.535  -0.578  -0.379
73    D        -0.308  -0.335  -0.624  -0.130  -0.155  -0.580  -0.321  -0.367  -0.753
74    L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
75    G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
76    I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
77    T         1.006   1.016   1.082   1.084   1.096   1.195   1.066   1.081   1.174
78    G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
79    V        -1.662  -1.691  -1.552  -1.803  -1.783  -1.540  -1.495  -1.504  -1.293
80    D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
81    Q         1.006   1.016   1.082   1.174   1.184   1.276   1.066   1.081   1.174
82    V        -0.175  -0.162  -0.053  -0.540  -0.524  -0.340  -0.535  -0.517  -0.362
83    R        -1.236  -1.330  -1.176  -1.234  -1.348  -1.122  -1.282  -1.349  -1.127
84    E         1.006   1.016   1.082   1.013   1.032   1.132   1.066   1.081   1.174
85    S        -0.734  -0.774  -0.691  -0.899  -0.909  -0.742  -0.962  -0.982  -0.847
86    N        -2.088  -2.012  -1.855  -1.955  -1.843  -1.617  -1.709  -1.634  -1.401
87    V        -2.088  -2.089  -1.865  -2.033  -2.093  -1.738  -1.709  -1.688  -1.408
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.867  -1.801  -1.575  -1.906  -1.826  -1.482  -1.666  -1.594  -1.311
114   D        -1.971  -1.990  -1.858  -1.788  -1.840  -1.661  -1.602  -1.610  -1.402
115   V        -0.734  -0.803  -0.689  -0.974  -1.039  -0.815  -0.962  -1.027  -0.847
116   D        -0.734  -0.661  -0.686  -0.838  -0.748  -0.718  -0.962  -0.882  -0.844
117   L        -1.662  -1.698  -1.558  -1.753  -1.790  -1.519  -1.495  -1.512  -1.297
118   A        -1.160  -1.127  -1.152  -1.403  -1.361  -1.353  -1.175  -1.126  -1.102
119   I        -1.352  -1.366  -1.188  -1.582  -1.567  -1.288  -1.388  -1.383  -1.139
120   D         0.333   0.207   0.051   0.425   0.263  -0.004   0.319   0.123  -0.171
121   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
122   Q        -1.160  -1.098  -1.152  -0.987  -0.938  -1.013  -1.175  -1.119  -1.103
123   F         1.006   1.016   1.082   1.188   1.205   1.289   1.066   1.081   1.174
124   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
125   N        -1.662  -1.635  -1.546  -1.626  -1.622  -1.443  -1.495  -1.467  -1.289
126   C         1.006   1.016   1.082   1.238   1.252   1.333   1.066   1.081   1.174
127   K         1.006   1.016   1.082   0.990   1.016   1.111   1.066   1.081   1.174
128   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
129   Q         1.006   1.016   1.082   1.174   1.184   1.276   1.066   1.081   1.174
130   V         0.002   0.077   0.010  -0.217  -0.100  -0.221  -0.215  -0.091  -0.245
131   Q         1.006   1.016   1.082   1.174   1.184   1.276   1.066   1.081   1.174
132   V         1.006   1.016   1.082   0.876   0.888   1.009   1.066   1.081   1.174
133   P         1.006   1.016   1.082   1.140   1.156   1.246   1.066   1.081   1.174
134   V        -0.926  -0.870  -0.716  -1.285  -1.196  -0.944  -1.175  -1.101  -0.878
135   N        -1.971  -1.863  -1.838  -1.824  -1.668  -1.663  -1.602  -1.500  -1.388
136   G         0.333   0.383   0.069   0.396   0.458   0.006   0.319   0.391  -0.139
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   E        -0.911  -0.899  -1.124  -0.723  -0.715  -1.058  -0.855  -0.846  -1.070
139   Y         0.002  -0.015  -0.032   0.138   0.099  -0.019  -0.215  -0.250  -0.323
140   K        -0.911  -0.924  -1.118  -0.696  -0.739  -1.078  -0.855  -0.878  -1.064
141   K        -1.352  -1.376  -1.187  -1.469  -1.479  -1.205  -1.388  -1.392  -1.138
142   P        -0.308  -0.520  -0.648  -0.069  -0.386  -0.668  -0.321  -0.610  -0.786
143   E        -0.734  -0.789  -0.691  -0.887  -0.950  -0.797  -0.962  -1.013  -0.849
144   Q         0.333   0.207   0.051   0.579   0.407   0.127   0.319   0.123  -0.171
145   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
146   I        -0.232  -0.205  -0.062  -0.645  -0.603  -0.354  -0.641  -0.599  -0.379
147   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
148   K         0.333   0.229   0.055   0.408   0.285   0.013   0.319   0.158  -0.164
149   T        -1.662  -1.698  -1.558  -1.526  -1.558  -1.370  -1.495  -1.512  -1.297
150   I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
151   V         0.333   0.207   0.051   0.277   0.105  -0.133   0.319   0.123  -0.171
152   T        -0.232  -0.195  -0.057  -0.468  -0.396  -0.180  -0.641  -0.581  -0.370
153   S         1.006   1.016   1.082   0.990   1.012   1.111   1.066   1.081   1.174
154   F         1.006   1.016   1.082   1.188   1.205   1.289   1.066   1.081   1.174
155   V        -0.734  -0.761  -0.688  -0.942  -0.970  -0.831  -0.962  -0.967  -0.844
156   K        -1.469  -1.514  -1.532  -1.170  -1.207  -1.219  -1.282  -1.332  -1.275
157   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
158   A        -1.236  -1.220  -1.164  -1.396  -1.388  -1.263  -1.282  -1.253  -1.116
159   E        -2.397  -2.350  -2.123  -2.229  -2.161  -1.856  -1.815  -1.764  -1.484
160   K        -0.926  -0.847  -0.715  -1.157  -1.020  -0.829  -1.175  -1.071  -0.877
161   Y         1.006   1.016   1.082   1.242   1.255   1.336   1.066   1.081   1.174
162   F         1.006   1.016   1.082   1.188   1.205   1.289   1.066   1.081   1.174
163   A        -1.160  -1.153  -1.154  -1.200  -1.181  -1.156  -1.175  -1.153  -1.103
164   D        -1.971  -1.956  -1.850  -1.633  -1.643  -1.535  -1.602  -1.584  -1.397
165   L         0.333   0.229   0.055   0.173   0.034  -0.246   0.319   0.158  -0.164
166   E         0.333   0.379   0.076   0.415   0.478   0.027   0.319   0.384  -0.126
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   G        -0.308  -0.198  -0.604  -0.166  -0.029  -0.587  -0.321  -0.177  -0.726
174   T        -1.236  -1.231  -1.160  -1.457  -1.452  -1.318  -1.282  -1.262  -1.112
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   T        -1.628  -1.664  -1.548  -1.477  -1.596  -1.454  -1.443  -1.475  -1.289
184   V        -1.274  -1.346  -1.181  -1.464  -1.563  -1.296  -1.303  -1.360  -1.131
185   E        -2.115  -2.028  -1.859  -2.016  -1.881  -1.658  -1.722  -1.639  -1.403
186   K        -1.054  -0.983  -1.133  -0.976  -0.878  -1.137  -1.025  -0.947  -1.080
187   M        -0.921  -0.853  -0.715  -1.217  -1.135  -0.888  -1.164  -1.073  -0.876
188   T        -1.778  -1.666  -1.556  -1.807  -1.639  -1.478  -1.602  -1.490  -1.297
189   T         1.006   1.016   1.082   1.084   1.096   1.195   1.066   1.081   1.174
190   R        -2.088  -2.077  -1.865  -1.829  -1.810  -1.544  -1.709  -1.680  -1.407
191   I         0.333   0.421   0.074   0.343   0.458  -0.066   0.319   0.444  -0.131
192   K        -1.160  -1.269  -1.172  -1.149  -1.303  -1.185  -1.175  -1.274  -1.121
193   F        -0.734  -0.799  -0.691  -0.584  -0.674  -0.541  -0.962  -1.021  -0.849
194   V         0.333   0.207   0.051   0.248   0.064  -0.213   0.319   0.123  -0.171
195   S        -0.175  -0.194  -0.062  -0.421  -0.469  -0.256  -0.535  -0.579  -0.379
196   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
197   S         1.006   1.016   1.082   0.990   1.012   1.111   1.066   1.081   1.174
198   V         1.006   1.016   1.082   0.876   0.888   1.009   1.066   1.081   1.174
199   E         1.006   1.016   1.082   1.013   1.032   1.132   1.066   1.081   1.174
200   A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
201   S         0.002  -0.027  -0.032  -0.115  -0.168  -0.228  -0.215  -0.272  -0.323
202   C         1.006   1.016   1.082   1.238   1.252   1.333   1.066   1.081   1.174
203   A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
204   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
205   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
206   I         0.002  -0.017  -0.033  -0.217  -0.257  -0.303  -0.215  -0.253  -0.325
207   G         0.002   0.077  -0.004  -0.155  -0.038  -0.189  -0.215  -0.091  -0.271
208   D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
209   A         0.002  -0.027  -0.032  -0.155  -0.212  -0.243  -0.215  -0.272  -0.323
210   I         0.333   0.229   0.055   0.343   0.202  -0.102   0.319   0.158  -0.164
211   V         0.333   0.416   0.072   0.273   0.374  -0.109   0.319   0.438  -0.133
212   D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
213   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
214   V         1.006   1.016   1.082   0.876   0.888   1.009   1.066   1.081   1.174
215   E         1.006   1.016   1.082   1.013   1.032   1.132   1.066   1.081   1.174
216   S         1.006   1.016   1.082   0.990   1.012   1.111   1.066   1.081   1.174
217   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
218   E         1.006   1.016   1.082   1.013   1.032   1.132   1.066   1.081   1.174
219   T         1.006   1.016   1.082   1.084   1.096   1.195   1.066   1.081   1.174
220   M         1.006   1.016   1.082   1.232   1.245   1.327   1.066   1.081   1.174
221   R        -0.175  -0.167  -0.055  -0.321  -0.316  -0.160  -0.535  -0.528  -0.366
222   A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
223   A         0.333   0.229   0.055   0.330   0.192  -0.082   0.319   0.158  -0.164
224   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
225   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
226   V        -1.662  -1.611  -1.540  -1.603  -1.499  -1.427  -1.495  -1.433  -1.283
227   D        -0.850  -0.808  -0.712  -1.023  -0.954  -0.802  -1.068  -1.010  -0.872
228   I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
229   A        -0.734  -0.801  -0.696  -0.942  -1.023  -0.843  -0.962  -1.025  -0.855
230   T         1.006   1.016   1.082   1.084   1.096   1.195   1.066   1.081   1.174
231   V         0.002   0.077   0.010  -0.217  -0.100  -0.221  -0.215  -0.091  -0.245
232   L        -0.308  -0.520  -0.648  -0.379  -0.667  -0.838  -0.321  -0.610  -0.786
233   S        -1.160  -1.053  -1.148  -1.123  -0.992  -1.097  -1.175  -1.067  -1.099
234   T         0.333   0.207   0.051   0.485   0.314   0.041   0.319   0.123  -0.171
235   S         1.006   1.016   1.082   0.990   1.012   1.111   1.066   1.081   1.174
236   A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
237   Y        -1.662  -1.698  -1.552  -1.343  -1.446  -1.289  -1.495  -1.512  -1.294
238   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
239   I         0.333   0.229   0.055   0.343   0.202  -0.102   0.319   0.158  -0.164
240   E        -2.088  -2.077  -1.870  -2.010  -1.985  -1.690  -1.709  -1.680  -1.411
241   S         0.333   0.383   0.069   0.383   0.454  -0.028   0.319   0.391  -0.139
242   K        -0.308  -0.365  -0.625  -0.182  -0.256  -0.655  -0.321  -0.405  -0.754
243   N        -1.160  -1.167  -1.157  -1.022  -1.032  -1.062  -1.175  -1.169  -1.106
244   P        -0.308  -0.369  -0.619  -0.010  -0.086  -0.479  -0.321  -0.410  -0.746
245   K        -0.734  -0.696  -0.689  -0.874  -0.825  -0.750  -0.962  -0.922  -0.846
246   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.780  -1.773  -1.570  -1.550  -1.583  -1.293  -1.590  -1.571  -1.308
251   -        -0.131  -0.144  -0.054  -0.186  -0.224  -0.121  -0.452  -0.484  -0.364
252   S        -0.308  -0.340  -0.620  -0.152  -0.192  -0.614  -0.321  -0.374  -0.748
253   L         0.002  -0.044  -0.034  -0.207  -0.268  -0.219  -0.215  -0.302  -0.327
254   I        -0.850  -0.806  -0.716  -1.256  -1.195  -1.065  -1.068  -1.008  -0.877
255   A        -2.088  -2.019  -1.857  -1.864  -1.770  -1.552  -1.709  -1.640  -1.402
256   T        -1.971  -1.894  -1.846  -1.784  -1.723  -1.674  -1.602  -1.528  -1.394
257   I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
258   K        -1.469  -1.543  -1.538  -1.321  -1.470  -1.467  -1.282  -1.359  -1.281
259   S        -1.160  -1.269  -1.172  -1.101  -1.259  -1.123  -1.175  -1.274  -1.121
260   R         1.006   1.016   1.082   1.103   1.115   1.212   1.066   1.081   1.174
261   I        -0.308  -0.198  -0.604  -0.232  -0.087  -0.686  -0.321  -0.177  -0.726
262   E        -1.160  -1.278  -1.167  -1.062  -1.230  -1.067  -1.175  -1.285  -1.118
263   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
264   V        -0.308  -0.336  -0.620  -0.304  -0.336  -0.757  -0.321  -0.369  -0.748
265   M        -0.926  -0.919  -0.731  -1.173  -1.179  -0.882  -1.175  -1.159  -0.896
266   T        -0.734  -0.761  -0.688  -0.879  -0.894  -0.798  -0.962  -0.967  -0.844
267   A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
268   Q         0.333   0.416   0.072   0.600   0.695   0.217   0.319   0.438  -0.133
269   R        -1.160  -1.156  -1.149  -1.094  -1.066  -1.059  -1.175  -1.156  -1.098
270   F         0.333   0.411   0.074   0.670   0.762   0.284   0.319   0.430  -0.130
271   V         1.006   1.016   1.082   0.876   0.888   1.009   1.066   1.081   1.174
272   S        -0.601  -0.480  -0.653  -0.800  -0.612  -0.805  -0.748  -0.575  -0.794
273   C         0.333   0.229   0.055   0.624   0.476   0.135   0.319   0.158  -0.164
274   I        -1.160  -1.144  -1.160  -1.000  -0.952  -1.033  -1.175  -1.145  -1.110
275   Y         1.006   1.016   1.082   1.242   1.255   1.336   1.066   1.081   1.174
276   N         1.006   1.016   1.082   1.165   1.183   1.268   1.066   1.081   1.174
277   A        -0.601  -0.652  -0.688  -0.741  -0.884  -0.886  -0.748  -0.848  -0.844
278   P        -0.308  -0.520  -0.648  -0.018  -0.310  -0.547  -0.321  -0.610  -0.786
279   E        -0.734  -0.650  -0.673  -0.805  -0.663  -0.697  -0.962  -0.843  -0.824
280   D        -2.088  -2.075  -1.866  -1.969  -1.949  -1.639  -1.709  -1.679  -1.408
281   K        -1.662  -1.715  -1.556  -1.537  -1.571  -1.318  -1.495  -1.525  -1.296
282   L         0.333   0.379   0.076   0.218   0.280  -0.093   0.319   0.384  -0.126
283   P        -1.662  -1.549  -1.539  -1.583  -1.443  -1.442  -1.495  -1.392  -1.283
284   E        -1.662  -1.711  -1.555  -1.724  -1.805  -1.592  -1.495  -1.520  -1.295
285   L        -1.160  -1.222  -1.169  -1.390  -1.503  -1.341  -1.175  -1.240  -1.120
286   L         0.333   0.207   0.051   0.204   0.048  -0.168   0.319   0.123  -0.171
287   K        -0.308  -0.198  -0.604  -0.154  -0.008  -0.562  -0.321  -0.177  -0.726
288   V         0.002   0.077  -0.004  -0.164  -0.037  -0.220  -0.215  -0.091  -0.271
289   T         1.006   1.016   1.082   1.084   1.096   1.195   1.066   1.081   1.174
290   P         1.006   1.016   1.082   1.140   1.156   1.246   1.066   1.081   1.174
291   G         1.006   1.016   1.082   0.990   1.003   1.111   1.066   1.081   1.174
292   R         0.002  -0.109  -0.047   0.014  -0.196  -0.142  -0.215  -0.420  -0.351
293   R         1.006   1.016   1.082   1.103   1.115   1.212   1.066   1.081   1.174
294   A         0.333   0.415   0.074   0.330   0.432  -0.049   0.319   0.436  -0.131
295   P        -0.175  -0.104  -0.037  -0.319  -0.180  -0.123  -0.535  -0.411  -0.332
296   T         1.006   1.016   1.082   1.084   1.096   1.195   1.066   1.081   1.174
297   I         0.002   0.078  -0.007  -0.164  -0.036  -0.227  -0.215  -0.090  -0.277
298   S         0.002  -0.109  -0.047  -0.065  -0.253  -0.173  -0.215  -0.420  -0.351
299   K        -2.088  -2.001  -1.858  -1.932  -1.821  -1.603  -1.709  -1.628  -1.403
300   I         0.002   0.100   0.010  -0.302  -0.140  -0.293  -0.215  -0.052  -0.245
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   D        -0.601  -0.558  -0.671  -0.586  -0.546  -0.688  -0.748  -0.711  -0.821
307   D        -1.160  -1.206  -1.169  -1.094  -1.176  -1.090  -1.175  -1.229  -1.120
308   E        -0.911  -0.895  -1.121  -0.723  -0.699  -1.054  -0.855  -0.842  -1.067
309   G        -0.308  -0.198  -0.604  -0.192  -0.050  -0.643  -0.321  -0.177  -0.726
310   W         1.006   1.016   1.082   1.317   1.329   1.404   1.066   1.081   1.174
311   V         0.333   0.416   0.072   0.315   0.409  -0.002   0.319   0.438  -0.133
312   A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
313   V         0.333   0.379   0.076   0.273   0.328  -0.102   0.319   0.384  -0.126
314   S         0.333   0.383   0.069   0.417   0.486   0.060   0.319   0.391  -0.139
315   S         0.333   0.207   0.051   0.383   0.216  -0.062   0.319   0.123  -0.171
316   M         1.006   1.016   1.082   1.232   1.245   1.327   1.066   1.081   1.174
317   I        -0.734  -0.621  -0.678  -1.042  -0.871  -0.921  -0.962  -0.812  -0.830
318   E        -0.308  -0.369  -0.619  -0.166  -0.261  -0.644  -0.321  -0.410  -0.746
319   R        -0.232  -0.196  -0.057  -0.454  -0.394  -0.178  -0.641  -0.582  -0.370
320   K         1.006   1.016   1.082   0.990   1.016   1.111   1.066   1.081   1.174
321   T        -1.778  -1.671  -1.554  -1.712  -1.565  -1.366  -1.602  -1.501  -1.296
322   K        -0.734  -0.760  -0.689  -0.964  -0.979  -0.884  -0.962  -0.965  -0.844
323   G        -0.734  -0.623  -0.673  -0.964  -0.798  -0.834  -0.962  -0.816  -0.825
324   V        -1.662  -1.654  -1.545  -1.513  -1.500  -1.347  -1.495  -1.480  -1.288
325   V        -0.232  -0.191  -0.057  -0.645  -0.580  -0.347  -0.641  -0.573  -0.370
326   L         0.333   0.411   0.074   0.606   0.707   0.139   0.319   0.430  -0.130
327   D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
328   E        -0.734  -0.787  -0.687  -0.875  -0.936  -0.784  -0.962  -1.009  -0.845
329   L         1.006   1.016   1.082   0.789   0.810   0.931   1.066   1.081   1.174
330   K        -0.308  -0.520  -0.648  -0.185  -0.470  -0.701  -0.321  -0.610  -0.786
331   R        -1.160  -1.269  -1.170  -1.078  -1.207  -1.059  -1.175  -1.273  -1.120
332   L        -2.088  -2.020  -1.859  -2.109  -2.007  -1.809  -1.709  -1.640  -1.404
333   G         0.333   0.229   0.055   0.435   0.310   0.085   0.319   0.158  -0.164
334   A         1.006   1.016   1.082   0.929   0.943   1.056   1.066   1.081   1.174
335   S        -1.160  -1.195  -1.162  -1.076  -1.118  -1.042  -1.175  -1.219  -1.113
336   D         1.006   1.016   1.082   1.020   1.040   1.138   1.066   1.081   1.174
337   I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
338   M        -0.734  -0.774  -0.691  -0.928  -0.981  -0.829  -0.962  -0.982  -0.847
339   V         1.006   1.016   1.082   0.876   0.888   1.009   1.066   1.081   1.174
340   F        -0.175  -0.197  -0.062  -0.346  -0.442  -0.248  -0.535  -0.585  -0.379
341   E        -0.850  -0.869  -0.726  -1.016  -1.052  -0.849  -1.068  -1.093  -0.890
342   I         1.006   1.016   1.082   0.957   0.977   1.082   1.066   1.081   1.174
343   S        -0.911  -1.038  -1.143  -0.716  -0.883  -1.045  -0.855  -1.012  -1.090
344   N         1.006   1.016   1.082   1.165   1.183   1.268   1.066   1.081   1.174
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   C         0.002  -0.109  -0.047   0.144  -0.073  -0.043  -0.215  -0.420  -0.351
349   R         1.006   1.016   1.082   1.103   1.115   1.212   1.066   1.081   1.174
350   V        -0.308  -0.520  -0.648  -0.299  -0.599  -0.789  -0.321  -0.610  -0.786
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P00498
Output conservation file - output/P00498
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
