1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     M        -0.253  -0.373  -0.396  -0.126  -0.405  -0.511  -0.325  -0.514  -0.548
4     T        -0.253  -0.373  -0.396  -0.217  -0.363  -0.395  -0.325  -0.514  -0.548
5     H        -1.407  -1.384  -1.344  -1.007  -1.003  -0.945  -1.302  -1.259  -1.191
6     L        -0.253  -0.257  -0.378  -0.148  -0.189  -0.478  -0.325  -0.338  -0.519
7     E        -1.407  -1.384  -1.344  -1.370  -1.427  -1.321  -1.302  -1.259  -1.191
8     R        -0.253  -0.373  -0.396   0.111  -0.129  -0.190  -0.325  -0.514  -0.548
9     S        -1.407  -1.384  -1.344  -1.362  -1.360  -1.292  -1.302  -1.259  -1.191
10    R        -1.407  -1.384  -1.344  -1.009  -0.937  -0.866  -1.302  -1.259  -1.191
11    H        -1.407  -1.384  -1.344  -1.671  -1.531  -1.424  -1.302  -1.259  -1.191
12    Q         1.106   1.120   1.136   1.422   1.427   1.440   1.140   1.162   1.180
13    Q        -1.407  -1.384  -1.344  -1.576  -1.409  -1.308  -1.302  -1.259  -1.191
14    H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
15    P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
16    F        -0.253  -0.373  -0.396  -0.182  -0.389  -0.414  -0.325  -0.514  -0.548
17    H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
18    M        -1.407  -1.384  -1.344  -1.665  -1.501  -1.418  -1.302  -1.259  -1.191
19    V         1.106   1.120   1.136   1.111   1.132   1.159   1.140   1.162   1.180
20    M        -1.407  -1.384  -1.344  -1.228  -1.201  -1.119  -1.302  -1.259  -1.191
21    P        -0.253  -0.373  -0.396  -0.010  -0.235  -0.291  -0.325  -0.514  -0.548
22    S         1.106   1.120   1.136   1.099   1.119   1.149   1.140   1.162   1.180
23    P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
24    W         1.106   1.120   1.136   1.309   1.320   1.338   1.140   1.162   1.180
25    P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
26    I        -0.253  -0.373  -0.396  -0.265  -0.445  -0.489  -0.325  -0.514  -0.548
27    V        -0.253  -0.257  -0.378  -0.186  -0.214  -0.390  -0.325  -0.338  -0.519
28    V        -1.407  -1.384  -1.344  -1.595  -1.632  -1.550  -1.302  -1.259  -1.191
29    S         1.106   1.120   1.136   1.099   1.119   1.149   1.140   1.162   1.180
30    F        -0.253  -0.373  -0.396  -0.186  -0.397  -0.420  -0.325  -0.514  -0.548
31    A        -1.407  -1.384  -1.344  -1.303  -1.304  -1.228  -1.302  -1.259  -1.191
32    L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
33    L        -1.407  -1.384  -1.344  -1.323  -1.401  -1.374  -1.302  -1.259  -1.191
34    S        -1.407  -1.384  -1.344  -1.068  -1.137  -1.074  -1.302  -1.259  -1.191
35    L        -0.253  -0.373  -0.396  -0.584  -0.674  -0.678  -0.325  -0.514  -0.548
36    A        -0.253  -0.373  -0.396  -0.082  -0.239  -0.239  -0.325  -0.514  -0.548
37    L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
38    S        -0.253  -0.373  -0.396  -0.186  -0.397  -0.430  -0.325  -0.514  -0.548
39    T        -1.407  -1.384  -1.344  -1.789  -1.647  -1.572  -1.302  -1.259  -1.191
40    A        -1.407  -1.384  -1.344  -1.372  -1.376  -1.304  -1.302  -1.259  -1.191
41    L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
42    T        -0.253  -0.373  -0.396  -0.271  -0.437  -0.483  -0.325  -0.514  -0.548
43    M        -1.407  -1.384  -1.344  -1.430  -1.485  -1.380  -1.302  -1.259  -1.191
44    H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
45    G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
46    Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
47    I        -0.253  -0.373  -0.396  -0.150  -0.277  -0.298  -0.325  -0.514  -0.548
48    G        -1.407  -1.384  -1.344  -1.274  -1.253  -1.177  -1.302  -1.259  -1.191
49    N        -0.253  -0.257  -0.378  -0.119  -0.131  -0.293  -0.325  -0.338  -0.519
50    M        -1.407  -1.384  -1.344  -1.281  -1.226  -1.153  -1.302  -1.259  -1.191
51    N        -1.407  -1.384  -1.344  -1.038  -1.069  -1.000  -1.302  -1.259  -1.191
52    M        -1.407  -1.384  -1.344  -1.061  -1.090  -1.014  -1.302  -1.259  -1.191
53    V        -1.407  -1.384  -1.344  -1.372  -1.343  -1.269  -1.302  -1.259  -1.191
54    Y        -1.407  -1.384  -1.344  -1.308  -1.309  -1.228  -1.302  -1.259  -1.191
55    L        -0.253  -0.373  -0.396  -0.681  -0.803  -0.839  -0.325  -0.514  -0.548
56    A        -0.253  -0.373  -0.396  -0.201  -0.409  -0.435  -0.325  -0.514  -0.548
57    L        -1.407  -1.384  -1.344  -1.589  -1.584  -1.554  -1.302  -1.259  -1.191
58    F        -1.407  -1.384  -1.344  -1.589  -1.639  -1.554  -1.302  -1.259  -1.191
59    V        -1.407  -1.384  -1.344  -1.323  -1.322  -1.240  -1.302  -1.259  -1.191
60    L        -0.569  -0.366  -0.376  -1.043  -0.755  -0.758  -0.813  -0.504  -0.516
61    L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
62    T        -1.407  -1.384  -1.344  -1.333  -1.339  -1.279  -1.302  -1.259  -1.191
63    S        -0.253  -0.373  -0.396  -0.212  -0.421  -0.473  -0.325  -0.514  -0.548
64    S        -0.253  -0.257  -0.378   0.018  -0.009  -0.228  -0.325  -0.338  -0.519
65    I        -1.407  -1.384  -1.344  -1.415  -1.359  -1.314  -1.302  -1.259  -1.191
66    L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
67    W         1.106   1.120   1.136   1.309   1.320   1.338   1.140   1.162   1.180
68    F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
69    R        -0.569  -0.366  -0.376  -0.246   0.025   0.011  -0.813  -0.504  -0.516
70    D         1.106   1.120   1.136   1.374   1.386   1.397   1.140   1.162   1.180
71    I        -0.253  -0.373  -0.396  -0.193  -0.331  -0.370  -0.325  -0.514  -0.548
72    V        -1.407  -1.384  -1.344  -1.367  -1.328  -1.263  -1.302  -1.259  -1.191
73    A        -0.253  -0.373  -0.396  -0.234  -0.447  -0.491  -0.325  -0.514  -0.548
74    E         1.106   1.120   1.136   1.368   1.367   1.392   1.140   1.162   1.180
75    A        -0.569  -0.366  -0.376  -0.714  -0.398  -0.400  -0.813  -0.504  -0.516
76    T        -0.253  -0.373  -0.396  -0.217  -0.363  -0.395  -0.325  -0.514  -0.548
77    Y        -0.253  -0.373  -0.396  -0.184  -0.385  -0.447  -0.325  -0.514  -0.548
78    L        -0.253  -0.373  -0.396  -0.606  -0.710  -0.714  -0.325  -0.514  -0.548
79    G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
80    D        -0.253  -0.373  -0.396   0.079  -0.157  -0.222  -0.325  -0.514  -0.548
81    H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
82    T         1.106   1.120   1.136   0.997   1.043   1.057   1.140   1.162   1.180
83    M        -1.407  -1.384  -1.344  -1.463  -1.248  -1.171  -1.302  -1.259  -1.191
84    A         1.106   1.120   1.136   1.077   1.090   1.129   1.140   1.162   1.180
85    V         1.106   1.120   1.136   1.111   1.132   1.159   1.140   1.162   1.180
86    R        -1.407  -1.384  -1.344  -0.931  -1.001  -0.928  -1.302  -1.259  -1.191
87    K        -0.569  -0.366  -0.376  -0.246   0.033   0.020  -0.813  -0.504  -0.516
88    G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
89    I        -0.253  -0.257  -0.378  -0.681  -0.632  -0.815  -0.325  -0.338  -0.519
90    N        -0.253  -0.373  -0.396   0.103  -0.080  -0.105  -0.325  -0.514  -0.548
91    L        -1.407  -1.384  -1.344  -1.247  -1.347  -1.344  -1.302  -1.259  -1.191
92    G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
93    F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
94    L        -0.253  -0.373  -0.396  -0.576  -0.659  -0.665  -0.325  -0.514  -0.548
95    M        -0.253  -0.257  -0.378  -0.576  -0.521  -0.651  -0.325  -0.338  -0.519
96    F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
97    V        -0.253  -0.373  -0.396  -0.319  -0.582  -0.668  -0.325  -0.514  -0.548
98    L        -1.407  -1.384  -1.344  -1.534  -1.558  -1.539  -1.302  -1.259  -1.191
99    S         1.106   1.120   1.136   1.099   1.119   1.149   1.140   1.162   1.180
100   E         1.106   1.120   1.136   1.368   1.367   1.392   1.140   1.162   1.180
101   V        -1.407  -1.384  -1.344  -1.412  -1.379  -1.321  -1.302  -1.259  -1.191
102   L        -0.253  -0.373  -0.396  -0.655  -0.784  -0.795  -0.325  -0.514  -0.548
103   I        -0.253  -0.373  -0.396  -0.416  -0.648  -0.747  -0.325  -0.514  -0.548
104   F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
105   A         1.106   1.120   1.136   1.077   1.090   1.129   1.140   1.162   1.180
106   G        -0.253  -0.257  -0.378  -0.186  -0.205  -0.398  -0.325  -0.338  -0.519
107   L        -0.253  -0.373  -0.396  -0.681  -0.803  -0.839  -0.325  -0.514  -0.548
108   F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
109   W         1.106   1.120   1.136   1.309   1.320   1.338   1.140   1.162   1.180
110   A         1.106   1.120   1.136   1.077   1.090   1.129   1.140   1.162   1.180
111   Y        -0.253  -0.373  -0.396  -0.161  -0.368  -0.407  -0.325  -0.514  -0.548
112   F        -0.569  -0.366  -0.376  -1.061  -0.601  -0.633  -0.813  -0.504  -0.516
113   H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
114   S         1.106   1.120   1.136   1.099   1.119   1.149   1.140   1.162   1.180
115   A        -0.253  -0.373  -0.396  -0.201  -0.409  -0.435  -0.325  -0.514  -0.548
116   M        -0.253  -0.257  -0.378  -0.576  -0.521  -0.651  -0.325  -0.338  -0.519
117   S        -0.569  -0.366  -0.376  -0.564  -0.286  -0.290  -0.813  -0.504  -0.516
118   P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
119   D        -0.253  -0.257  -0.378  -0.186  -0.164  -0.323  -0.325  -0.338  -0.519
120   V        -1.407  -1.384  -1.344  -1.123  -1.175  -1.107  -1.302  -1.259  -1.191
121   T        -1.407  -1.384  -1.344  -0.993  -1.005  -0.977  -1.302  -1.259  -1.191
122   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
123   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
124   A        -0.569  -0.366  -0.376  -0.564  -0.298  -0.296  -0.813  -0.504  -0.516
125   C        -1.407  -1.384  -1.344  -0.873  -0.922  -0.846  -1.302  -1.259  -1.191
126   W         1.106   1.120   1.136   1.309   1.320   1.338   1.140   1.162   1.180
127   P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
128   P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
129   V         1.106   1.120   1.136   1.111   1.132   1.159   1.140   1.162   1.180
130   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
131   I         1.106   1.120   1.136   1.014   1.063   1.072   1.140   1.162   1.180
132   E        -1.407  -1.384  -1.344  -1.038  -1.069  -0.985  -1.302  -1.259  -1.191
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   A        -0.253  -0.257  -0.378  -0.285  -0.282  -0.478  -0.325  -0.338  -0.519
136   V        -0.253  -0.257  -0.378  -0.258  -0.246  -0.447  -0.325  -0.338  -0.519
137   Q        -1.407  -1.384  -1.344  -1.043  -0.965  -0.897  -1.302  -1.259  -1.191
138   P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
139   T        -1.407  -1.384  -1.344  -1.573  -1.651  -1.572  -1.302  -1.259  -1.191
140   E         1.106   1.120   1.136   1.368   1.367   1.392   1.140   1.162   1.180
141   L        -0.253  -0.373  -0.396  -0.647  -0.764  -0.781  -0.325  -0.514  -0.548
142   P         1.106   1.120   1.136   1.282   1.299   1.314   1.140   1.162   1.180
143   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
144   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
145   N         1.106   1.120   1.136   1.282   1.292   1.314   1.140   1.162   1.180
146   T         1.106   1.120   1.136   0.997   1.043   1.057   1.140   1.162   1.180
147   I        -0.253  -0.373  -0.396  -0.258  -0.427  -0.477  -0.325  -0.514  -0.548
148   I         1.106   1.120   1.136   1.014   1.063   1.072   1.140   1.162   1.180
149   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
150   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
151   S        -1.407  -1.384  -1.344  -1.362  -1.367  -1.292  -1.302  -1.259  -1.191
152   S         1.106   1.120   1.136   1.099   1.119   1.149   1.140   1.162   1.180
153   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
154   A        -0.569  -0.366  -0.376  -0.706  -0.392  -0.394  -0.813  -0.504  -0.516
155   T        -0.253  -0.373  -0.396  -0.278  -0.451  -0.496  -0.325  -0.514  -0.548
156   V        -0.253  -0.373  -0.396  -0.319  -0.582  -0.668  -0.325  -0.514  -0.548
157   T         1.106   1.120   1.136   0.997   1.043   1.057   1.140   1.162   1.180
158   Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
159   S        -0.253  -0.257  -0.378  -0.201  -0.225  -0.404  -0.325  -0.338  -0.519
160   H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
161   H        -0.253  -0.373  -0.396  -0.054  -0.271  -0.313  -0.325  -0.514  -0.548
162   A        -0.253  -0.373  -0.396  -0.201  -0.409  -0.435  -0.325  -0.514  -0.548
163   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
164   I         1.106   1.120   1.136   1.014   1.063   1.072   1.140   1.162   1.180
165   A        -0.569  -0.366  -0.376  -0.580  -0.312  -0.307  -0.813  -0.504  -0.516
166   G        -0.253  -0.373  -0.396  -0.101  -0.255  -0.271  -0.325  -0.514  -0.548
167   N         1.106   1.120   1.136   1.282   1.292   1.314   1.140   1.162   1.180
168   R         1.106   1.120   1.136   1.400   1.403   1.421   1.140   1.162   1.180
169   N        -1.407  -1.384  -1.344  -1.188  -1.091  -1.026  -1.302  -1.259  -1.191
170   K        -0.253  -0.257  -0.378   0.103   0.080  -0.080  -0.325  -0.338  -0.519
171   A        -0.569  -0.366  -0.376  -0.789  -0.436  -0.452  -0.813  -0.504  -0.516
172   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
173   S        -1.407  -1.384  -1.344  -1.134  -1.079  -1.023  -1.302  -1.259  -1.191
174   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
175   L        -0.569  -0.366  -0.376  -1.061  -0.775  -0.770  -0.813  -0.504  -0.516
176   L        -1.407  -1.384  -1.344  -1.589  -1.560  -1.543  -1.302  -1.259  -1.191
177   I        -1.407  -1.384  -1.344  -1.226  -1.176  -1.140  -1.302  -1.259  -1.191
178   T         1.106   1.120   1.136   0.997   1.043   1.057   1.140   1.162   1.180
179   F        -1.407  -1.384  -1.344  -1.430  -1.398  -1.334  -1.302  -1.259  -1.191
180   W        -1.407  -1.384  -1.344  -1.289  -1.243  -1.162  -1.302  -1.259  -1.191
181   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
182   I        -0.253  -0.373  -0.396  -0.261  -0.433  -0.483  -0.325  -0.514  -0.548
183   V        -1.407  -1.384  -1.344  -1.318  -1.325  -1.234  -1.302  -1.259  -1.191
184   I        -0.253  -0.257  -0.378  -0.681  -0.632  -0.815  -0.325  -0.338  -0.519
185   F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
186   V        -0.253  -0.373  -0.396  -0.319  -0.582  -0.668  -0.325  -0.514  -0.548
187   T        -1.407  -1.384  -1.344  -1.333  -1.332  -1.279  -1.302  -1.259  -1.191
188   C        -1.407  -1.384  -1.344  -1.160  -1.144  -1.038  -1.302  -1.259  -1.191
189   Q         1.106   1.120   1.136   1.422   1.427   1.440   1.140   1.162   1.180
190   Y        -0.253  -0.373  -0.396  -0.164  -0.372  -0.413  -0.325  -0.514  -0.548
191   I        -1.407  -1.384  -1.344  -1.757  -1.592  -1.532  -1.302  -1.259  -1.191
192   E         1.106   1.120   1.136   1.368   1.367   1.392   1.140   1.162   1.180
193   Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
194   T        -1.407  -1.384  -1.344  -1.250  -1.203  -1.159  -1.302  -1.259  -1.191
195   N        -0.569  -0.366  -0.376  -0.548  -0.203  -0.229  -0.813  -0.504  -0.516
196   A         1.106   1.120   1.136   1.077   1.090   1.129   1.140   1.162   1.180
197   A        -1.407  -1.384  -1.344  -1.247  -1.205  -1.143  -1.302  -1.259  -1.191
198   F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
199   T         1.106   1.120   1.136   0.997   1.043   1.057   1.140   1.162   1.180
200   I        -0.569  -0.366  -0.376  -1.120  -0.634  -0.695  -0.813  -0.504  -0.516
201   S         1.106   1.120   1.136   1.099   1.119   1.149   1.140   1.162   1.180
202   D         1.106   1.120   1.136   1.374   1.386   1.397   1.140   1.162   1.180
203   G        -0.253  -0.373  -0.396  -0.201  -0.399  -0.435  -0.325  -0.514  -0.548
204   V         1.106   1.120   1.136   1.111   1.132   1.159   1.140   1.162   1.180
205   Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
206   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
207   S        -0.253  -0.373  -0.396  -0.186  -0.397  -0.430  -0.325  -0.514  -0.548
208   V        -1.407  -1.384  -1.344  -1.382  -1.341  -1.272  -1.302  -1.259  -1.191
209   F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
210   Y        -0.569  -0.366  -0.376  -0.690  -0.358  -0.371  -0.813  -0.504  -0.516
211   A        -1.407  -1.384  -1.344  -1.313  -1.328  -1.240  -1.302  -1.259  -1.191
212   G        -1.407  -1.384  -1.344  -1.749  -1.612  -1.522  -1.302  -1.259  -1.191
213   T         1.106   1.120   1.136   0.997   1.043   1.057   1.140   1.162   1.180
214   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
215   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
216   H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
217   F        -0.253  -0.257  -0.378  -0.204  -0.224  -0.410  -0.325  -0.338  -0.519
218   L        -0.253  -0.373  -0.396  -0.681  -0.803  -0.839  -0.325  -0.514  -0.548
219   H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
220   M        -0.253  -0.373  -0.396  -0.008  -0.231  -0.307  -0.325  -0.514  -0.548
221   V        -0.253  -0.257  -0.378  -0.258  -0.246  -0.447  -0.325  -0.338  -0.519
222   M        -0.253  -0.373  -0.396   0.022  -0.198  -0.257  -0.325  -0.514  -0.548
223   L        -0.253  -0.373  -0.396  -0.659  -0.781  -0.802  -0.325  -0.514  -0.548
224   A        -0.253  -0.257  -0.378  -0.285  -0.282  -0.478  -0.325  -0.338  -0.519
225   A        -0.253  -0.257  -0.378  -0.269  -0.263  -0.465  -0.325  -0.338  -0.519
226   M        -0.253  -0.373  -0.396  -0.126  -0.405  -0.511  -0.325  -0.514  -0.548
227   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
228   G        -1.407  -1.384  -1.344  -1.328  -1.449  -1.380  -1.302  -1.259  -1.191
229   V        -0.569  -0.366  -0.376  -0.752  -0.388  -0.417  -0.813  -0.504  -0.516
230   N        -1.407  -1.384  -1.344  -0.927  -1.011  -0.936  -1.302  -1.259  -1.191
231   Y        -0.253  -0.257  -0.378  -0.271  -0.259  -0.455  -0.325  -0.338  -0.519
232   W        -0.253  -0.373  -0.396   0.030  -0.189  -0.247  -0.325  -0.514  -0.548
233   R        -0.253  -0.373  -0.396   0.167  -0.047  -0.097  -0.325  -0.514  -0.548
234   M        -1.407  -1.384  -1.344  -1.236  -1.218  -1.146  -1.302  -1.259  -1.191
235   R        -0.253  -0.257  -0.378  -0.059  -0.061  -0.216  -0.325  -0.338  -0.519
236   N        -0.253  -0.373  -0.396  -0.034  -0.264  -0.333  -0.325  -0.514  -0.548
237   Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
238   H        -0.569  -0.366  -0.376  -0.412  -0.145  -0.151  -0.813  -0.504  -0.516
239   L        -0.569  -0.366  -0.376  -1.061  -0.775  -0.770  -0.813  -0.504  -0.516
240   T         1.106   1.120   1.136   0.997   1.043   1.057   1.140   1.162   1.180
241   A        -0.253  -0.257  -0.378  -0.010  -0.045  -0.255  -0.325  -0.338  -0.519
242   G        -0.253  -0.257  -0.378  -0.285  -0.277  -0.478  -0.325  -0.338  -0.519
243   H        -0.569  -0.366  -0.376  -0.608  -0.274  -0.287  -0.813  -0.504  -0.516
244   H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
245   V        -0.253  -0.373  -0.396  -0.109  -0.285  -0.311  -0.325  -0.514  -0.548
246   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
247   Y        -1.407  -1.384  -1.344  -1.313  -1.316  -1.228  -1.302  -1.259  -1.191
248   E         1.106   1.120   1.136   1.368   1.367   1.392   1.140   1.162   1.180
249   T        -0.253  -0.373  -0.396  -0.157  -0.280  -0.296  -0.325  -0.514  -0.548
250   T        -0.253  -0.373  -0.396  -0.285  -0.461  -0.508  -0.325  -0.514  -0.548
251   I         1.106   1.120   1.136   1.014   1.063   1.072   1.140   1.162   1.180
252   I        -1.407  -1.384  -1.344  -1.757  -1.592  -1.532  -1.302  -1.259  -1.191
253   Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
254   T        -1.407  -1.384  -1.344  -1.671  -1.476  -1.424  -1.302  -1.259  -1.191
255   H         1.106   1.120   1.136   1.222   1.228   1.260   1.140   1.162   1.180
256   V        -0.253  -0.373  -0.396  -0.172  -0.383  -0.416  -0.325  -0.514  -0.548
257   L        -0.253  -0.373  -0.396  -0.519  -0.584  -0.571  -0.325  -0.514  -0.548
258   D         1.106   1.120   1.136   1.374   1.386   1.397   1.140   1.162   1.180
259   V         1.106   1.120   1.136   1.111   1.132   1.159   1.140   1.162   1.180
260   I        -0.253  -0.373  -0.396  -0.258  -0.427  -0.477  -0.325  -0.514  -0.548
261   W         1.106   1.120   1.136   1.309   1.320   1.338   1.140   1.162   1.180
262   L         1.106   1.120   1.136   0.618   0.693   0.714   1.140   1.162   1.180
263   F         1.106   1.120   1.136   1.088   1.097   1.139   1.140   1.162   1.180
264   L        -0.569  -0.366  -0.376  -1.120  -0.793  -0.812  -0.813  -0.504  -0.516
265   Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
266   V        -1.407  -1.384  -1.344  -1.579  -1.617  -1.539  -1.302  -1.259  -1.191
267   V        -1.407  -1.384  -1.344  -1.412  -1.379  -1.321  -1.302  -1.259  -1.191
268   F        -1.407  -1.384  -1.344  -1.330  -1.339  -1.269  -1.302  -1.259  -1.191
269   Y         1.106   1.120   1.136   1.122   1.148   1.169   1.140   1.162   1.180
270   W        -0.253  -0.373  -0.396  -0.003  -0.229  -0.303  -0.325  -0.514  -0.548
271   W         1.106   1.120   1.136   1.309   1.320   1.338   1.140   1.162   1.180
272   G         1.106   1.120   1.136   1.077   1.101   1.129   1.140   1.162   1.180
273   V        -0.253  -0.257  -0.378  -0.175  -0.193  -0.381  -0.325  -0.338  -0.519
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P00420
Output conservation file - output/P00420
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
