1     M         1.000   1.008   1.017   1.203   1.215   1.217   1.033   1.041   1.050
2     L        -0.559  -0.495  -0.593  -0.980  -0.870  -1.021  -0.661  -0.560  -0.703
3     D        -1.691  -1.646  -1.608  -1.404  -1.331  -1.270  -1.508  -1.441  -1.381
4     L        -0.559  -0.629  -0.623  -0.811  -0.903  -0.850  -0.661  -0.760  -0.748
5     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    T        -0.698  -0.680  -0.639  -0.625  -0.593  -0.527  -0.873  -0.838  -0.773
12    F        -0.698  -0.680  -0.639  -0.780  -0.737  -0.674  -0.873  -0.838  -0.773
13    I         1.000   1.008   1.017   0.803   0.816   0.836   1.033   1.041   1.050
14    M        -0.698  -0.680  -0.639  -0.896  -0.861  -0.785  -0.873  -0.838  -0.773
15    N         1.000   1.008   1.017   1.141   1.150   1.158   1.033   1.041   1.050
16    D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
17    V        -0.559  -0.629  -0.623  -0.608  -0.704  -0.683  -0.661  -0.760  -0.748
18    P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
19    T        -0.559  -0.629  -0.623  -0.495  -0.612  -0.610  -0.661  -0.760  -0.748
20    P        -0.559  -0.629  -0.623  -0.495  -0.618  -0.610  -0.661  -0.760  -0.748
21    Y        -0.559  -0.468  -0.590  -0.309  -0.161  -0.374  -0.661  -0.521  -0.698
22    A        -0.559  -0.495  -0.593  -0.454  -0.348  -0.507  -0.661  -0.560  -0.703
23    C        -1.691  -1.646  -1.608  -1.794  -1.760  -1.642  -1.508  -1.441  -1.381
24    Y        -0.559  -0.495  -0.593  -0.406  -0.308  -0.443  -0.661  -0.560  -0.703
25    F        -0.559  -0.495  -0.593  -0.615  -0.500  -0.705  -0.661  -0.560  -0.703
26    Q         1.000   1.008   1.017   1.195   1.204   1.210   1.033   1.041   1.050
27    D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
28    S        -0.559  -0.629  -0.623  -0.543  -0.654  -0.631  -0.661  -0.760  -0.748
29    A         1.000   1.008   1.017   1.067   1.079   1.088   1.033   1.041   1.050
30    T        -0.559  -0.629  -0.623  -0.495  -0.612  -0.610  -0.661  -0.760  -0.748
31    P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
32    N        -0.559  -0.629  -0.623  -0.406  -0.542  -0.536  -0.661  -0.760  -0.748
33    Q        -1.691  -1.646  -1.608  -1.409  -1.341  -1.274  -1.508  -1.441  -1.381
34    E        -0.559  -0.629  -0.623  -0.708  -0.855  -0.860  -0.661  -0.760  -0.748
35    G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
36    I        -0.559  -0.629  -0.623  -0.831  -0.928  -0.912  -0.661  -0.760  -0.748
37    L        -1.691  -1.646  -1.608  -1.606  -1.505  -1.462  -1.508  -1.441  -1.381
38    E        -0.559  -0.629  -0.623  -0.447  -0.528  -0.511  -0.661  -0.760  -0.748
39    L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
40    H        -1.691  -1.646  -1.608  -1.329  -1.256  -1.198  -1.508  -1.441  -1.381
41    D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
42    N        -1.691  -1.646  -1.608  -1.329  -1.271  -1.198  -1.508  -1.441  -1.381
43    I        -0.559  -0.629  -0.623  -0.942  -1.071  -1.060  -0.661  -0.760  -0.748
44    M         1.000   1.008   1.017   1.203   1.215   1.217   1.033   1.041   1.050
45    F         1.000   1.008   1.017   1.083   1.090   1.103   1.033   1.041   1.050
46    Y         1.000   1.008   1.017   1.043   1.056   1.065   1.033   1.041   1.050
47    L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
48    L        -1.691  -1.646  -1.608  -1.590  -1.492  -1.447  -1.508  -1.441  -1.381
49    V        -1.691  -1.646  -1.608  -1.816  -1.705  -1.663  -1.508  -1.441  -1.381
50    I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
51    L        -0.559  -0.629  -0.623  -0.811  -0.903  -0.850  -0.661  -0.760  -0.748
52    G        -0.559  -0.629  -0.623  -0.604  -0.740  -0.753  -0.661  -0.760  -0.748
53    L        -0.559  -0.629  -0.623  -0.823  -0.915  -0.866  -0.661  -0.760  -0.748
54    V         1.000   1.008   1.017   0.895   0.907   0.923   1.033   1.041   1.050
55    S        -0.559  -0.629  -0.623  -0.689  -0.827  -0.825  -0.661  -0.760  -0.748
56    W        -0.559  -0.468  -0.590  -0.396  -0.261  -0.426  -0.661  -0.521  -0.698
57    M        -1.691  -1.646  -1.608  -1.580  -1.487  -1.438  -1.508  -1.441  -1.381
58    L        -0.559  -0.629  -0.623  -0.980  -1.102  -1.074  -0.661  -0.760  -0.748
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    Y        -0.559  -0.629  -0.623  -0.472  -0.577  -0.570  -0.661  -0.760  -0.748
62    T        -0.559  -0.468  -0.590  -0.608  -0.463  -0.637  -0.661  -0.521  -0.698
63    I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
64    V        -1.691  -1.646  -1.608  -1.832  -1.716  -1.678  -1.508  -1.441  -1.381
65    M        -1.691  -1.646  -1.608  -1.324  -1.261  -1.193  -1.508  -1.441  -1.381
66    T        -1.691  -1.646  -1.608  -1.442  -1.351  -1.306  -1.508  -1.441  -1.381
67    Y         1.000   1.008   1.017   1.043   1.056   1.065   1.033   1.041   1.050
68    S        -1.691  -1.646  -1.608  -1.390  -1.309  -1.256  -1.508  -1.441  -1.381
69    K        -1.691  -1.646  -1.608  -1.476  -1.419  -1.339  -1.508  -1.441  -1.381
70    N        -0.559  -0.629  -0.623  -0.288  -0.393  -0.379  -0.661  -0.760  -0.748
71    P        -0.559  -0.495  -0.593  -0.385  -0.288  -0.424  -0.661  -0.560  -0.703
72    I        -0.559  -0.495  -0.593  -0.740  -0.632  -0.756  -0.661  -0.560  -0.703
73    A         1.000   1.008   1.017   1.067   1.079   1.088   1.033   1.041   1.050
74    Y        -0.559  -0.629  -0.623  -0.472  -0.577  -0.570  -0.661  -0.760  -0.748
75    K         1.000   1.008   1.017   1.203   1.215   1.217   1.033   1.041   1.050
76    Y         1.000   1.008   1.017   1.043   1.056   1.065   1.033   1.041   1.050
77    I        -1.691  -1.646  -1.608  -1.778  -1.649  -1.626  -1.508  -1.441  -1.381
78    K        -1.691  -1.646  -1.608  -1.306  -1.241  -1.176  -1.508  -1.441  -1.381
79    H         1.000   1.008   1.017   1.234   1.243   1.247   1.033   1.041   1.050
80    G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
81    Q        -0.559  -0.629  -0.623  -0.377  -0.510  -0.511  -0.661  -0.760  -0.748
82    T        -1.691  -1.646  -1.608  -1.778  -1.712  -1.626  -1.508  -1.441  -1.381
83    I        -0.559  -0.629  -0.623  -0.831  -0.928  -0.912  -0.661  -0.760  -0.748
84    E         1.000   1.008   1.017   0.986   1.003   1.010   1.033   1.041   1.050
85    V        -1.691  -1.646  -1.608  -1.767  -1.649  -1.616  -1.508  -1.441  -1.381
86    I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
87    W         1.000   1.008   1.017   1.234   1.241   1.247   1.033   1.041   1.050
88    T         1.000   1.008   1.017   1.067   1.085   1.088   1.033   1.041   1.050
89    I        -0.559  -0.629  -0.623  -0.942  -1.071  -1.060  -0.661  -0.760  -0.748
90    F        -0.559  -0.629  -0.623  -0.581  -0.722  -0.734  -0.661  -0.760  -0.748
91    P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
92    A         1.000   1.008   1.017   1.067   1.079   1.088   1.033   1.041   1.050
93    V        -0.559  -0.629  -0.623  -0.795  -0.942  -0.934  -0.661  -0.760  -0.748
94    I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
95    L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
96    L        -0.559  -0.629  -0.623  -0.980  -1.102  -1.074  -0.661  -0.760  -0.748
97    I        -0.559  -0.468  -0.590  -0.980  -0.826  -1.015  -0.661  -0.521  -0.698
98    I        -0.559  -0.629  -0.623  -0.831  -0.928  -0.912  -0.661  -0.760  -0.748
99    A         1.000   1.008   1.017   1.067   1.079   1.088   1.033   1.041   1.050
100   F        -0.559  -0.629  -0.623  -0.615  -0.777  -0.780  -0.661  -0.760  -0.748
101   P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
102   S         1.000   1.008   1.017   0.969   0.972   0.994   1.033   1.041   1.050
103   F         1.000   1.008   1.017   1.083   1.090   1.103   1.033   1.041   1.050
104   I        -0.559  -0.629  -0.623  -0.681  -0.743  -0.713  -0.661  -0.760  -0.748
105   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
106   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
107   Y         1.000   1.008   1.017   1.043   1.056   1.065   1.033   1.041   1.050
108   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
109   C        -0.559  -0.629  -0.623  -0.450  -0.619  -0.638  -0.661  -0.760  -0.748
110   D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
111   E         1.000   1.008   1.017   0.986   1.003   1.010   1.033   1.041   1.050
112   V         1.000   1.008   1.017   0.895   0.907   0.923   1.033   1.041   1.050
113   I        -1.691  -1.646  -1.608  -1.838  -1.693  -1.683  -1.508  -1.441  -1.381
114   S        -1.691  -1.646  -1.608  -1.447  -1.345  -1.311  -1.508  -1.441  -1.381
115   P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
116   A        -0.559  -0.629  -0.623  -0.495  -0.618  -0.610  -0.661  -0.760  -0.748
117   M         1.000   1.008   1.017   1.203   1.215   1.217   1.033   1.041   1.050
118   T         1.000   1.008   1.017   1.067   1.085   1.088   1.033   1.041   1.050
119   I        -0.559  -0.629  -0.623  -0.831  -0.928  -0.912  -0.661  -0.760  -0.748
120   K         1.000   1.008   1.017   1.203   1.215   1.217   1.033   1.041   1.050
121   A        -0.559  -0.495  -0.593  -0.528  -0.415  -0.595  -0.661  -0.560  -0.703
122   I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
123   G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
124   Y        -1.691  -1.646  -1.608  -1.636  -1.524  -1.491  -1.508  -1.441  -1.381
125   Q         1.000   1.008   1.017   1.195   1.204   1.210   1.033   1.041   1.050
126   W         1.000   1.008   1.017   1.234   1.241   1.247   1.033   1.041   1.050
127   Y        -0.559  -0.629  -0.623  -0.465  -0.571  -0.560  -0.661  -0.760  -0.748
128   W         1.000   1.008   1.017   1.234   1.241   1.247   1.033   1.041   1.050
129   K        -0.559  -0.629  -0.623  -0.370  -0.500  -0.505  -0.661  -0.760  -0.748
130   Y         1.000   1.008   1.017   1.043   1.056   1.065   1.033   1.041   1.050
131   E         1.000   1.008   1.017   0.986   1.003   1.010   1.033   1.041   1.050
132   Y        -0.559  -0.629  -0.623  -0.654  -0.807  -0.813  -0.661  -0.760  -0.748
133   S        -0.559  -0.629  -0.623  -0.495  -0.598  -0.567  -0.661  -0.760  -0.748
134   D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
135   F         1.000   1.008   1.017   1.083   1.090   1.103   1.033   1.041   1.050
136   I        -0.559  -0.468  -0.590  -0.759  -0.591  -0.817  -0.661  -0.521  -0.698
137   N        -1.691  -1.646  -1.608  -1.442  -1.366  -1.306  -1.508  -1.441  -1.381
138   D        -1.691  -1.646  -1.608  -1.501  -1.411  -1.362  -1.508  -1.441  -1.381
139   S        -1.691  -1.646  -1.608  -1.783  -1.680  -1.632  -1.508  -1.441  -1.381
140   G        -0.559  -0.629  -0.623  -0.414  -0.516  -0.500  -0.661  -0.760  -0.748
141   E         1.000   1.008   1.017   0.986   1.003   1.010   1.033   1.041   1.050
142   T        -0.559  -0.629  -0.623  -0.450  -0.553  -0.551  -0.661  -0.760  -0.748
143   V        -0.559  -0.495  -0.593  -0.759  -0.637  -0.823  -0.661  -0.560  -0.703
144   E        -0.559  -0.629  -0.623  -0.570  -0.683  -0.674  -0.661  -0.760  -0.748
145   F         1.000   1.008   1.017   1.083   1.090   1.103   1.033   1.041   1.050
146   E        -0.559  -0.629  -0.623  -0.547  -0.649  -0.644  -0.661  -0.760  -0.748
147   S         1.000   1.008   1.017   0.969   0.972   0.994   1.033   1.041   1.050
148   Y         1.000   1.008   1.017   1.043   1.056   1.065   1.033   1.041   1.050
149   V        -0.559  -0.629  -0.623  -0.543  -0.624  -0.599  -0.661  -0.760  -0.748
150   I        -0.559  -0.629  -0.623  -0.831  -0.928  -0.912  -0.661  -0.760  -0.748
151   P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
152   D        -0.559  -0.629  -0.623  -0.532  -0.641  -0.638  -0.661  -0.760  -0.748
153   E        -0.559  -0.495  -0.593  -0.547  -0.435  -0.595  -0.661  -0.560  -0.703
154   L        -1.691  -1.646  -1.608  -1.657  -1.561  -1.511  -1.508  -1.441  -1.381
155   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
156   E         1.000   1.008   1.017   0.986   1.003   1.010   1.033   1.041   1.050
157   E        -0.559  -0.495  -0.593  -0.524  -0.415  -0.568  -0.661  -0.560  -0.703
158   G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
159   Q        -1.691  -1.646  -1.608  -1.452  -1.400  -1.315  -1.508  -1.441  -1.381
160   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
161   R         1.000   1.008   1.017   1.211   1.217   1.225   1.033   1.041   1.050
162   L        -0.559  -0.629  -0.623  -0.755  -0.833  -0.776  -0.661  -0.760  -0.748
163   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
164   D        -0.559  -0.629  -0.623  -0.532  -0.641  -0.638  -0.661  -0.760  -0.748
165   T        -0.559  -0.629  -0.623  -0.528  -0.648  -0.655  -0.661  -0.760  -0.748
166   D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
167   T        -0.559  -0.629  -0.623  -0.406  -0.503  -0.493  -0.661  -0.760  -0.748
168   S        -0.559  -0.629  -0.623  -0.472  -0.569  -0.538  -0.661  -0.760  -0.748
169   M        -1.691  -1.646  -1.608  -1.832  -1.792  -1.678  -1.508  -1.441  -1.381
170   V         1.000   1.008   1.017   0.895   0.907   0.923   1.033   1.041   1.050
171   V        -0.559  -0.629  -0.623  -0.795  -0.942  -0.934  -0.661  -0.760  -0.748
172   P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
173   V        -0.559  -0.629  -0.623  -0.759  -0.885  -0.886  -0.661  -0.760  -0.748
174   D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
175   T         1.000   1.008   1.017   1.067   1.085   1.088   1.033   1.041   1.050
176   H        -0.559  -0.629  -0.623  -0.235  -0.344  -0.340  -0.661  -0.760  -0.748
177   I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
178   R         1.000   1.008   1.017   1.211   1.217   1.225   1.033   1.041   1.050
179   F        -0.559  -0.629  -0.623  -0.615  -0.777  -0.780  -0.661  -0.760  -0.748
180   V        -0.559  -0.629  -0.623  -0.759  -0.885  -0.886  -0.661  -0.760  -0.748
181   V        -0.559  -0.629  -0.623  -0.795  -0.942  -0.934  -0.661  -0.760  -0.748
182   T         1.000   1.008   1.017   1.067   1.085   1.088   1.033   1.041   1.050
183   A        -0.559  -0.629  -0.623  -0.495  -0.618  -0.610  -0.661  -0.760  -0.748
184   A        -1.691  -1.646  -1.608  -1.418  -1.349  -1.283  -1.508  -1.441  -1.381
185   D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
186   V         1.000   1.008   1.017   0.895   0.907   0.923   1.033   1.041   1.050
187   I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
188   H         1.000   1.008   1.017   1.234   1.243   1.247   1.033   1.041   1.050
189   D        -0.559  -0.468  -0.590  -0.562  -0.423  -0.603  -0.661  -0.521  -0.698
190   F        -0.559  -0.629  -0.623  -0.359  -0.457  -0.438  -0.661  -0.760  -0.748
191   A        -0.559  -0.495  -0.593  -0.450  -0.342  -0.502  -0.661  -0.560  -0.703
192   I        -0.559  -0.629  -0.623  -0.831  -0.928  -0.912  -0.661  -0.760  -0.748
193   P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
194   S         1.000   1.008   1.017   0.969   0.972   0.994   1.033   1.041   1.050
195   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
196   G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
197   I        -0.559  -0.495  -0.593  -0.681  -0.576  -0.686  -0.661  -0.560  -0.703
198   K         1.000   1.008   1.017   1.203   1.215   1.217   1.033   1.041   1.050
199   V        -1.691  -1.646  -1.608  -1.652  -1.514  -1.506  -1.508  -1.441  -1.381
200   D         1.000   1.008   1.017   1.018   1.032   1.041   1.033   1.041   1.050
201   A        -0.559  -0.629  -0.623  -0.363  -0.452  -0.436  -0.661  -0.760  -0.748
202   T        -0.559  -0.629  -0.623  -0.596  -0.727  -0.747  -0.661  -0.760  -0.748
203   P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
204   G        -0.559  -0.629  -0.623  -0.502  -0.625  -0.617  -0.661  -0.760  -0.748
205   R         1.000   1.008   1.017   1.211   1.217   1.225   1.033   1.041   1.050
206   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
207   N         1.000   1.008   1.017   1.163   1.166   1.180   1.033   1.041   1.050
208   Q         1.000   1.008   1.017   1.195   1.204   1.210   1.033   1.041   1.050
209   V         1.000   1.008   1.017   0.895   0.907   0.923   1.033   1.041   1.050
210   S         1.000   1.008   1.017   0.969   0.972   0.994   1.033   1.041   1.050
211   A        -0.559  -0.629  -0.623  -0.631  -0.787  -0.793  -0.661  -0.760  -0.748
212   L        -0.559  -0.629  -0.623  -0.868  -0.976  -0.925  -0.661  -0.760  -0.748
213   I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
214   Q        -0.559  -0.629  -0.623  -0.356  -0.478  -0.483  -0.661  -0.760  -0.748
215   R         1.000   1.008   1.017   1.211   1.217   1.225   1.033   1.041   1.050
216   E        -0.559  -0.495  -0.593  -0.524  -0.412  -0.568  -0.661  -0.560  -0.703
217   G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
218   V        -0.559  -0.629  -0.623  -0.795  -0.942  -0.934  -0.661  -0.760  -0.748
219   F        -0.559  -0.495  -0.593  -0.447  -0.344  -0.502  -0.661  -0.560  -0.703
220   Y         1.000   1.008   1.017   1.043   1.056   1.065   1.033   1.041   1.050
221   G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
222   A        -0.559  -0.468  -0.590  -0.334  -0.187  -0.393  -0.661  -0.521  -0.698
223   C         1.000   1.008   1.017   1.258   1.266   1.270   1.033   1.041   1.050
224   S         1.000   1.008   1.017   0.969   0.972   0.994   1.033   1.041   1.050
225   E         1.000   1.008   1.017   0.986   1.003   1.010   1.033   1.041   1.050
226   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
227   C         1.000   1.008   1.017   1.258   1.266   1.270   1.033   1.041   1.050
228   G         1.000   1.008   1.017   1.059   1.070   1.080   1.033   1.041   1.050
229   T        -0.559  -0.468  -0.590  -0.608  -0.463  -0.637  -0.661  -0.521  -0.698
230   G        -1.691  -1.646  -1.608  -1.657  -1.638  -1.511  -1.508  -1.441  -1.381
231   H         1.000   1.008   1.017   1.234   1.243   1.247   1.033   1.041   1.050
232   A        -1.691  -1.646  -1.608  -1.535  -1.472  -1.395  -1.508  -1.441  -1.381
233   N        -1.691  -1.646  -1.608  -1.390  -1.344  -1.256  -1.508  -1.441  -1.381
234   M         1.000   1.008   1.017   1.203   1.215   1.217   1.033   1.041   1.050
235   P         1.000   1.008   1.017   1.067   1.078   1.088   1.033   1.041   1.050
236   I         1.000   1.008   1.017   0.742   0.766   0.778   1.033   1.041   1.050
237   K        -0.559  -0.629  -0.623  -0.403  -0.535  -0.549  -0.661  -0.760  -0.748
238   I        -1.691  -1.646  -1.608  -2.049  -1.935  -1.885  -1.508  -1.441  -1.381
239   E        -0.559  -0.629  -0.623  -0.465  -0.551  -0.535  -0.661  -0.760  -0.748
240   A        -1.691  -1.646  -1.608  -1.362  -1.294  -1.229  -1.508  -1.441  -1.381
241   V         1.000   1.008   1.017   0.895   0.907   0.923   1.033   1.041   1.050
242   S         1.000   1.008   1.017   0.969   0.972   0.994   1.033   1.041   1.050
243   L        -0.559  -0.495  -0.593  -0.980  -0.870  -1.021  -0.661  -0.560  -0.703
244   P        -0.559  -0.468  -0.590  -0.524  -0.375  -0.563  -0.661  -0.521  -0.698
245   K        -0.559  -0.468  -0.590  -0.432  -0.294  -0.462  -0.661  -0.521  -0.698
246   F         1.000   1.008   1.017   1.083   1.090   1.103   1.033   1.041   1.050
247   L        -0.559  -0.495  -0.593  -0.980  -0.870  -1.021  -0.661  -0.560  -0.703
248   E        -0.559  -0.629  -0.623  -0.524  -0.622  -0.614  -0.661  -0.760  -0.748
249   W         1.000   1.008   1.017   1.234   1.241   1.247   1.033   1.041   1.050
250   L         1.000   1.008   1.017   0.665   0.667   0.704   1.033   1.041   1.050
251   N        -1.691  -1.646  -1.608  -1.467  -1.402  -1.329  -1.508  -1.441  -1.381
252   E         1.000   1.008   1.017   0.986   1.003   1.010   1.033   1.041   1.050
253   Q        -0.559  -0.468  -0.590  -0.306  -0.174  -0.351  -0.661  -0.521  -0.698
254   -        -0.698  -0.680  -0.639  -0.844  -0.799  -0.735  -0.873  -0.838  -0.773
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P00410
Output conservation file - output/P00410
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
