1     M         0.820   0.832   0.868   1.084   1.092   1.119   0.860   0.878   0.930
2     -        -0.105  -0.293  -0.350  -0.260  -0.556  -0.680  -0.169  -0.472  -0.605
3     V        -0.590  -0.563  -0.391  -1.008  -0.985  -0.682  -0.969  -0.935  -0.676
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     R        -1.103  -0.972  -1.083  -1.120  -0.945  -1.073  -1.244  -1.080  -1.158
6     V        -0.486  -0.359  -0.365  -0.857  -0.646  -0.649  -0.786  -0.581  -0.631
7     A        -0.486  -0.403  -0.359  -0.840  -0.692  -0.647  -0.786  -0.654  -0.620
8     I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
9     N         0.820   0.832   0.868   0.958   0.971   1.013   0.860   0.878   0.930
10    G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
11    F         0.820   0.832   0.868   1.013   1.028   1.059   0.860   0.878   0.930
12    G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
13    R         0.820   0.832   0.868   1.011   1.024   1.058   0.860   0.878   0.930
14    I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
15    G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
16    R         0.820   0.832   0.868   1.011   1.024   1.058   0.860   0.878   0.930
17    L        -0.590  -0.563  -0.390  -0.823  -0.795  -0.517  -0.969  -0.936  -0.674
18    V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
19    M        -0.583  -0.744  -1.060  -0.248  -0.452  -0.858  -0.512  -0.735  -1.127
20    R         0.820   0.832   0.868   1.011   1.024   1.058   0.860   0.878   0.930
21    I        -1.357  -1.211  -1.118  -1.511  -1.260  -1.201  -1.518  -1.339  -1.200
22    A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
23    L        -0.267  -0.373  -0.373  -0.233  -0.415  -0.477  -0.420  -0.604  -0.645
24    Q        -3.057  -2.980  -2.660  -2.705  -2.601  -2.252  -2.250  -2.179  -1.820
25    R        -1.854  -1.959  -2.033  -1.295  -1.448  -1.668  -1.518  -1.633  -1.622
26    K        -2.306  -2.308  -2.036  -2.256  -2.254  -1.885  -1.975  -1.957  -1.626
27    N        -2.186  -2.098  -2.036  -1.974  -1.869  -1.789  -1.884  -1.794  -1.625
28    V        -0.486  -0.451  -0.380  -0.772  -0.723  -0.648  -0.786  -0.738  -0.657
29    E        -1.538  -1.592  -1.616  -1.141  -1.206  -1.275  -1.426  -1.481  -1.447
30    V         0.104  -0.126  -0.318   0.009  -0.285  -0.570   0.128  -0.207  -0.549
31    V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
32    A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
33    L        -0.922  -0.810  -1.072  -1.054  -0.901  -1.237  -0.969  -0.830  -1.145
34    N         0.820   0.832   0.868   0.958   0.971   1.013   0.860   0.878   0.930
35    D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
36    P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
37    F         0.820   0.832   0.868   1.013   1.028   1.059   0.860   0.878   0.930
38    I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
39    S        -2.306  -2.264  -2.046  -2.338  -2.244  -1.946  -1.975  -1.922  -1.633
40    N        -2.306  -2.182  -2.035  -2.116  -1.943  -1.792  -1.975  -1.856  -1.625
41    D        -1.103  -1.230  -1.096  -1.122  -1.294  -1.103  -1.244  -1.366  -1.176
42    Y         0.820   0.832   0.868   1.015   1.024   1.061   0.860   0.878   0.930
43    S        -0.922  -0.799  -1.062  -0.936  -0.776  -1.106  -0.969  -0.814  -1.131
44    A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
45    Y         0.820   0.832   0.868   1.015   1.024   1.061   0.860   0.878   0.930
46    M         0.820   0.832   0.868   1.084   1.092   1.119   0.860   0.878   0.930
47    F         0.104  -0.126  -0.318   0.424   0.129  -0.227   0.128  -0.207  -0.549
48    K         0.104  -0.126  -0.318   0.190  -0.086  -0.357   0.128  -0.207  -0.549
49    Y         0.820   0.832   0.868   1.015   1.024   1.061   0.860   0.878   0.930
50    D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
51    S         0.104  -0.126  -0.318   0.173  -0.122  -0.443   0.128  -0.207  -0.549
52    T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
53    H         0.820   0.832   0.868   1.086   1.097   1.121   0.860   0.878   0.930
54    G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
55    R         0.104  -0.126  -0.318   0.433   0.141  -0.193   0.128  -0.207  -0.549
56    Y        -0.590  -0.505  -0.377  -0.568  -0.434  -0.271  -0.969  -0.833  -0.652
57    A        -1.673  -1.536  -1.617  -1.789  -1.585  -1.624  -1.609  -1.461  -1.449
58    G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
59    E        -1.538  -1.675  -1.627  -1.321  -1.530  -1.546  -1.426  -1.558  -1.457
60    V         0.104  -0.126  -0.318   0.009  -0.285  -0.570   0.128  -0.207  -0.549
61    S        -1.357  -1.234  -1.113  -1.463  -1.252  -1.128  -1.518  -1.359  -1.194
62    H        -2.622  -2.580  -2.379  -2.364  -2.386  -2.186  -2.067  -2.023  -1.742
63    D        -1.160  -1.035  -1.096  -1.340  -1.182  -1.199  -1.335  -1.206  -1.177
64    D        -1.103  -1.077  -1.088  -1.217  -1.213  -1.156  -1.244  -1.226  -1.167
65    K        -2.306  -2.284  -2.046  -2.378  -2.373  -1.986  -1.975  -1.932  -1.633
66    H        -2.425  -2.353  -2.045  -2.353  -2.270  -1.858  -2.067  -1.987  -1.632
67    I        -0.267  -0.162  -0.328  -0.233  -0.074  -0.386  -0.420  -0.262  -0.565
68    I        -0.590  -0.543  -0.388  -1.038  -0.965  -0.683  -0.969  -0.899  -0.671
69    V        -0.267  -0.370  -0.379  -0.365  -0.563  -0.644  -0.420  -0.600  -0.655
70    D         0.104  -0.126  -0.318   0.232  -0.051  -0.343   0.128  -0.207  -0.549
71    G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
72    H        -1.673  -1.508  -1.605  -1.446  -1.259  -1.281  -1.609  -1.430  -1.439
73    K        -1.538  -1.449  -1.610  -1.455  -1.314  -1.560  -1.426  -1.319  -1.442
74    I        -0.267  -0.382  -0.379  -0.365  -0.585  -0.645  -0.420  -0.619  -0.655
75    A        -2.306  -2.210  -2.038  -2.288  -2.123  -1.839  -1.975  -1.871  -1.627
76    T        -0.583  -0.744  -1.060  -0.553  -0.751  -1.152  -0.512  -0.735  -1.127
77    F        -1.103  -1.205  -1.097  -0.828  -0.939  -0.816  -1.244  -1.329  -1.177
78    Q        -1.793  -1.859  -1.636  -1.533  -1.657  -1.427  -1.701  -1.746  -1.466
79    E         0.820   0.832   0.868   0.938   0.951   0.995   0.860   0.878   0.930
80    R         0.104   0.187  -0.299   0.409   0.503  -0.236   0.128   0.237  -0.516
81    D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
82    P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
83    A         0.104   0.073  -0.306   0.040   0.011  -0.530   0.128   0.084  -0.528
84    N        -1.854  -1.892  -2.014  -1.435  -1.558  -1.839  -1.518  -1.570  -1.607
85    L        -0.486  -0.403  -0.359  -0.650  -0.517  -0.467  -0.786  -0.654  -0.620
86    P        -0.267  -0.187  -0.329  -0.137  -0.023  -0.322  -0.420  -0.301  -0.568
87    W         0.820   0.832   0.868   1.133   1.142   1.160   0.860   0.878   0.930
88    A        -1.103  -1.066  -1.098  -1.332  -1.304  -1.315  -1.244  -1.221  -1.177
89    S        -2.306  -2.202  -2.039  -2.298  -2.142  -1.931  -1.975  -1.882  -1.628
90    L        -2.622  -2.587  -2.374  -2.429  -2.419  -2.046  -2.067  -2.030  -1.739
91    N        -0.486  -0.403  -0.359  -0.691  -0.564  -0.486  -0.786  -0.654  -0.620
92    I        -1.357  -1.224  -1.109  -1.811  -1.585  -1.398  -1.518  -1.351  -1.190
93    D         0.104   0.164  -0.298   0.230   0.300  -0.319   0.128   0.207  -0.514
94    I        -0.486  -0.403  -0.359  -0.481  -0.347  -0.345  -0.786  -0.654  -0.620
95    A        -1.103  -1.210  -1.099  -1.462  -1.583  -1.386  -1.244  -1.337  -1.178
96    I        -0.267  -0.411  -0.378  -0.365  -0.642  -0.642  -0.420  -0.669  -0.653
97    D        -0.486  -0.403  -0.359  -0.542  -0.405  -0.391  -0.786  -0.654  -0.620
98    S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
99    T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
100   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
101   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
102   F         0.820   0.832   0.868   1.013   1.028   1.059   0.860   0.878   0.930
103   K        -0.486  -0.403  -0.359  -0.699  -0.558  -0.519  -0.786  -0.654  -0.620
104   E        -1.673  -1.555  -1.616  -1.635  -1.484  -1.575  -1.609  -1.481  -1.447
105   L        -1.793  -1.770  -1.637  -1.712  -1.725  -1.483  -1.701  -1.687  -1.468
106   D        -0.486  -0.403  -0.359  -0.542  -0.405  -0.391  -0.786  -0.654  -0.620
107   T        -2.109  -2.167  -2.037  -2.074  -2.177  -2.051  -1.792  -1.828  -1.625
108   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
109   Q        -0.590  -0.563  -0.390  -0.641  -0.638  -0.385  -0.969  -0.936  -0.674
110   K        -0.590  -0.563  -0.390  -1.010  -0.983  -0.680  -0.969  -0.936  -0.674
111   H         0.820   0.832   0.868   1.086   1.097   1.121   0.860   0.878   0.930
112   I        -0.590  -0.563  -0.390  -0.836  -0.792  -0.513  -0.969  -0.936  -0.674
113   D        -0.590  -0.563  -0.390  -0.892  -0.861  -0.573  -0.969  -0.936  -0.674
114   A        -0.590  -0.515  -0.380  -1.060  -0.918  -0.692  -0.969  -0.849  -0.657
115   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
116   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
117   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
118   K        -0.267  -0.187  -0.329  -0.280  -0.168  -0.373  -0.420  -0.301  -0.568
119   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
120   V        -0.486  -0.403  -0.359  -0.772  -0.625  -0.598  -0.786  -0.654  -0.620
121   I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
122   T        -0.590  -0.563  -0.390  -0.898  -0.864  -0.576  -0.969  -0.936  -0.674
123   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
124   P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
125   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
126   S        -1.793  -1.794  -1.632  -1.960  -1.993  -1.769  -1.701  -1.696  -1.463
127   T        -0.486  -0.403  -0.359  -0.668  -0.529  -0.491  -0.786  -0.654  -0.620
128   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
129   P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
130   M         0.820   0.832   0.868   1.084   1.092   1.119   0.860   0.878   0.930
131   F        -0.267  -0.369  -0.374  -0.034  -0.202  -0.265  -0.420  -0.598  -0.646
132   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
133   M        -0.267  -0.370  -0.379  -0.405  -0.548  -0.502  -0.420  -0.600  -0.655
134   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
135   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
136   N         0.820   0.832   0.868   0.958   0.971   1.013   0.860   0.878   0.930
137   E        -0.922  -1.100  -1.091  -0.693  -0.934  -0.976  -0.969  -1.182  -1.169
138   E        -1.160  -1.065  -1.091  -1.148  -1.028  -0.960  -1.335  -1.229  -1.170
139   K        -0.583  -0.829  -1.069  -0.455  -0.794  -1.218  -0.512  -0.835  -1.139
140   Y        -0.267  -0.187  -0.329  -0.033   0.070  -0.187  -0.420  -0.301  -0.568
141   T        -1.673  -1.788  -1.628  -1.600  -1.756  -1.530  -1.609  -1.695  -1.459
142   S        -1.222  -1.221  -1.110  -1.195  -1.243  -1.148  -1.335  -1.347  -1.191
143   D        -1.103  -1.085  -1.099  -1.179  -1.185  -1.129  -1.244  -1.239  -1.179
144   L        -1.670  -1.755  -1.634  -1.463  -1.610  -1.444  -1.571  -1.643  -1.464
145   K        -0.922  -1.109  -1.094  -0.914  -1.181  -1.191  -0.969  -1.194  -1.173
146   I        -0.590  -0.563  -0.390  -1.008  -0.992  -0.684  -0.969  -0.936  -0.674
147   V        -0.590  -0.524  -0.382  -1.008  -0.882  -0.654  -0.969  -0.865  -0.661
148   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
149   N         0.820   0.832   0.868   0.958   0.971   1.013   0.860   0.878   0.930
150   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
151   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
152   C         0.820   0.832   0.868   1.150   1.160   1.175   0.860   0.878   0.930
153   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
154   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
155   N         0.820   0.832   0.868   0.958   0.971   1.013   0.860   0.878   0.930
156   C         0.820   0.832   0.868   1.150   1.160   1.175   0.860   0.878   0.930
157   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
158   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
159   P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
160   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
161   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
162   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
163   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
164   I        -0.486  -0.431  -0.380  -0.772  -0.681  -0.647  -0.786  -0.702  -0.657
165   N        -0.583  -0.710  -1.058  -0.191  -0.359  -0.875  -0.512  -0.697  -1.125
166   D        -0.583  -0.458  -1.037  -0.338  -0.195  -0.947  -0.512  -0.361  -1.099
167   A        -1.870  -1.919  -1.641  -2.064  -2.091  -1.657  -1.792  -1.809  -1.471
168   F         0.104   0.073  -0.306   0.442   0.406  -0.148   0.128   0.084  -0.528
169   G         0.104  -0.126  -0.318   0.102  -0.195  -0.497   0.128  -0.207  -0.549
170   I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
171   E        -0.583  -0.829  -1.069  -0.281  -0.645  -1.106  -0.512  -0.835  -1.139
172   E         0.820   0.832   0.868   0.938   0.951   0.995   0.860   0.878   0.930
173   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
174   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
175   M         0.820   0.832   0.868   1.084   1.092   1.119   0.860   0.878   0.930
176   T         0.104   0.144  -0.299   0.192   0.240  -0.400   0.128   0.180  -0.516
177   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
178   V         0.104   0.144  -0.299   0.009   0.061  -0.537   0.128   0.180  -0.516
179   H         0.820   0.832   0.868   1.086   1.097   1.121   0.860   0.878   0.930
180   S        -0.267  -0.187  -0.329  -0.373  -0.247  -0.530  -0.420  -0.301  -0.568
181   M        -2.109  -2.094  -2.030  -1.848  -1.831  -1.684  -1.792  -1.775  -1.620
182   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
183   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
184   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
185   Q         0.820   0.832   0.868   1.109   1.124   1.140   0.860   0.878   0.930
186   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
187   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
188   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
189   D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
190   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
191   P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
192   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
193   H        -1.538  -1.624  -1.617  -1.148  -1.309  -1.361  -1.426  -1.510  -1.448
194   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
195   D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
196   W         0.820   0.832   0.868   1.133   1.142   1.160   0.860   0.878   0.930
197   R         0.820   0.832   0.868   1.011   1.024   1.058   0.860   0.878   0.930
198   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
199   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
200   R         0.820   0.832   0.868   1.011   1.024   1.058   0.860   0.878   0.930
201   T        -0.267  -0.187  -0.329  -0.336  -0.217  -0.488  -0.420  -0.301  -0.568
202   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
203   S         0.104  -0.126  -0.318   0.155  -0.154  -0.507   0.128  -0.207  -0.549
204   G        -0.922  -1.051  -1.084  -0.971  -1.101  -1.149  -0.969  -1.115  -1.158
205   N         0.820   0.832   0.868   0.958   0.971   1.013   0.860   0.878   0.930
206   I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
207   I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
208   P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
209   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
210   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
211   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
212   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
213   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
214   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
215   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
216   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
217   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
218   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
219   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
220   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
221   L        -0.486  -0.403  -0.359  -0.650  -0.517  -0.467  -0.786  -0.654  -0.620
222   P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
223   E        -1.538  -1.577  -1.614  -1.299  -1.378  -1.428  -1.426  -1.467  -1.445
224   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
225   Q        -0.486  -0.403  -0.359  -0.389  -0.268  -0.232  -0.786  -0.654  -0.620
226   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
227   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
228   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
229   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
230   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
231   M         0.820   0.832   0.868   1.084   1.092   1.119   0.860   0.878   0.930
232   A        -0.486  -0.415  -0.373  -0.834  -0.712  -0.647  -0.786  -0.676  -0.644
233   F        -1.103  -1.218  -1.102  -0.924  -1.041  -0.901  -1.244  -1.348  -1.182
234   R         0.820   0.832   0.868   1.011   1.024   1.058   0.860   0.878   0.930
235   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
236   P         0.820   0.832   0.868   0.978   0.991   1.030   0.860   0.878   0.930
237   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
238   V        -1.538  -1.557  -1.614  -1.579  -1.643  -1.689  -1.426  -1.449  -1.445
239   D         0.104  -0.126  -0.318   0.232  -0.051  -0.343   0.128  -0.207  -0.549
240   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
241   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
242   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
243   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
244   D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
245   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
246   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
247   V         0.104  -0.126  -0.318  -0.010  -0.317  -0.636   0.128  -0.207  -0.549
248   K        -0.590  -0.563  -0.391  -0.768  -0.718  -0.445  -0.969  -0.936  -0.676
249   L        -0.267  -0.411  -0.378  -0.233  -0.484  -0.486  -0.420  -0.669  -0.653
250   N        -2.186  -2.170  -2.035  -2.112  -2.089  -1.772  -1.884  -1.858  -1.625
251   K         0.104   0.073  -0.306   0.183   0.153  -0.360   0.128   0.084  -0.528
252   E        -2.306  -2.166  -2.045  -2.179  -2.048  -1.899  -1.975  -1.861  -1.632
253   T        -0.590  -0.522  -0.384  -1.008  -0.896  -0.653  -0.969  -0.863  -0.664
254   T        -1.222  -1.117  -1.095  -1.271  -1.119  -1.117  -1.335  -1.201  -1.172
255   Y         0.820   0.832   0.868   1.015   1.024   1.061   0.860   0.878   0.930
256   D        -0.590  -0.563  -0.391  -0.756  -0.731  -0.464  -0.969  -0.935  -0.676
257   E        -0.486  -0.444  -0.375  -0.542  -0.481  -0.425  -0.786  -0.725  -0.649
258   I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
259   K        -0.583  -0.391  -1.041  -0.458  -0.222  -1.173  -0.512  -0.280  -1.103
260   K        -1.793  -1.685  -1.624  -1.847  -1.721  -1.513  -1.701  -1.607  -1.456
261   V        -1.160  -1.137  -1.099  -1.580  -1.525  -1.388  -1.335  -1.288  -1.179
262   V        -0.583  -0.559  -1.045  -0.387  -0.357  -1.047  -0.512  -0.486  -1.109
263   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
264   A        -1.103  -1.033  -1.088  -1.303  -1.242  -1.158  -1.244  -1.187  -1.167
265   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
266   A         0.104   0.170  -0.298   0.155   0.239  -0.467   0.128   0.215  -0.514
267   E         0.104   0.187  -0.299   0.360   0.451  -0.215   0.128   0.237  -0.516
268   G        -0.583  -0.584  -1.048  -0.472  -0.475  -1.103  -0.512  -0.516  -1.113
269   K        -1.222  -1.082  -1.096  -1.115  -0.904  -1.004  -1.335  -1.156  -1.174
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   L        -0.267  -0.187  -0.329  -0.150  -0.039  -0.259  -0.420  -0.301  -0.568
272   K         0.104  -0.126  -0.318   0.143  -0.166  -0.516   0.128  -0.207  -0.549
273   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
274   V        -0.590  -0.563  -0.390  -1.038  -0.985  -0.676  -0.969  -0.936  -0.674
275   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
276   G         0.104  -0.126  -0.318   0.083  -0.228  -0.563   0.128  -0.207  -0.549
277   Y         0.820   0.832   0.868   1.015   1.024   1.061   0.860   0.878   0.930
278   T         0.820   0.832   0.868   0.793   0.810   0.873   0.860   0.878   0.930
279   E         0.104   0.073  -0.306   0.341   0.303  -0.286   0.128   0.084  -0.528
280   D         0.104   0.073  -0.306   0.230   0.197  -0.331   0.128   0.084  -0.528
281   A        -1.238  -1.416  -1.603  -1.118  -1.358  -1.614  -1.061  -1.275  -1.434
282   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
283   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
284   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
285   S        -0.590  -0.563  -0.391  -0.898  -0.863  -0.578  -0.969  -0.935  -0.676
286   D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
287   F         0.104  -0.126  -0.318   0.450   0.172  -0.140   0.128  -0.207  -0.549
288   L        -1.538  -1.675  -1.627  -1.204  -1.384  -1.345  -1.426  -1.558  -1.457
289   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
290   D        -0.922  -1.007  -1.081  -0.848  -0.934  -1.082  -0.969  -1.057  -1.154
291   S        -2.306  -2.306  -2.043  -2.175  -2.162  -1.794  -1.975  -1.958  -1.630
292   N        -2.306  -2.264  -2.046  -1.869  -1.874  -1.598  -1.975  -1.922  -1.633
293   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
294   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
295   I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
296   F         0.820   0.832   0.868   1.013   1.028   1.059   0.860   0.878   0.930
297   D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
298   A        -0.583  -0.391  -1.041  -0.483  -0.264  -1.008  -0.512  -0.280  -1.103
299   A        -1.357  -1.255  -1.113  -1.671  -1.498  -1.307  -1.518  -1.389  -1.194
300   A         0.820   0.832   0.868   0.642   0.665   0.746   0.860   0.878   0.930
301   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
302   I         0.820   0.832   0.868   0.789   0.803   0.870   0.860   0.878   0.930
303   Q        -1.538  -1.639  -1.621  -1.137  -1.293  -1.419  -1.426  -1.516  -1.452
304   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
305   S        -0.267  -0.411  -0.378  -0.284  -0.509  -0.463  -0.420  -0.669  -0.653
306   P        -0.583  -0.829  -1.069  -0.217  -0.565  -1.009  -0.512  -0.835  -1.139
307   K        -1.990  -1.908  -1.644  -1.923  -1.801  -1.433  -1.884  -1.799  -1.474
308   F         0.820   0.832   0.868   1.013   1.028   1.059   0.860   0.878   0.930
309   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
310   K         0.820   0.832   0.868   0.760   0.780   0.846   0.860   0.878   0.930
311   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
312   V        -0.486  -0.415  -0.373  -0.857  -0.741  -0.661  -0.786  -0.676  -0.644
313   S         0.104   0.144  -0.299   0.173   0.225  -0.408   0.128   0.180  -0.516
314   W         0.820   0.832   0.868   1.133   1.142   1.160   0.860   0.878   0.930
315   Y         0.820   0.832   0.868   1.015   1.024   1.061   0.860   0.878   0.930
316   D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
317   N         0.820   0.832   0.868   0.958   0.971   1.013   0.860   0.878   0.930
318   E         0.820   0.832   0.868   0.938   0.951   0.995   0.860   0.878   0.930
319   Y        -1.103  -1.053  -1.098  -0.803  -0.769  -0.794  -1.244  -1.210  -1.178
320   G         0.820   0.832   0.868   0.700   0.719   0.795   0.860   0.878   0.930
321   Y         0.820   0.832   0.868   1.015   1.024   1.061   0.860   0.878   0.930
322   S         0.820   0.832   0.868   0.772   0.793   0.856   0.860   0.878   0.930
323   T        -1.538  -1.587  -1.625  -1.332  -1.428  -1.440  -1.426  -1.499  -1.457
324   R         0.820   0.832   0.868   1.011   1.024   1.058   0.860   0.878   0.930
325   V         0.820   0.832   0.868   0.608   0.631   0.718   0.860   0.878   0.930
326   V         0.104  -0.126  -0.318   0.020  -0.264  -0.533   0.128  -0.207  -0.549
327   D         0.820   0.832   0.868   0.810   0.828   0.888   0.860   0.878   0.930
328   L         0.820   0.832   0.868   0.872   0.895   0.940   0.860   0.878   0.930
329   V        -1.222  -1.221  -1.113  -1.468  -1.492  -1.286  -1.335  -1.350  -1.195
330   E        -1.538  -1.675  -1.627  -1.400  -1.618  -1.675  -1.426  -1.558  -1.457
331   H        -1.673  -1.654  -1.628  -1.342  -1.343  -1.368  -1.609  -1.584  -1.459
332   V        -0.922  -1.051  -1.084  -1.067  -1.237  -1.285  -0.969  -1.115  -1.158
333   A         0.104  -0.126  -0.318   0.040  -0.253  -0.552   0.128  -0.207  -0.549
334   K        -0.583  -0.472  -1.050  -0.458  -0.318  -1.190  -0.512  -0.377  -1.115
335   -        -1.256  -1.314  -1.116  -1.584  -1.690  -1.394  -1.404  -1.460  -1.198
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   A        -0.602  -0.558  -0.390  -0.893  -0.852  -0.555  -0.992  -0.927  -0.674
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P00358
Output conservation file - output/P00358
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
